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Ketanserin

3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-1H-quinazoline-2,4-dione · also: Taseron · Serefrex · ketensin · Perketal · Ketaserin · Ketanserina

FormulaC22H22FN3O3
Mol. weight395.4344
PubChem CID3822
InChIKeyFPCCSQOGAWCVBH-UHFFFAOYSA-N
SMILESC1CN(CCC1C(=O)C2=CC=C(C=C2)F)CCN3C(=O)C4=CC=CC=C4NC3=O
21,123Patents
3,659Research papers3,661 indexed in detail
1,354Patents - last 3 years
30Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Pfizer Inc722
2Boston Scientific Corp507
3Bristol Myers Squibb Co446
4Johnson and Johnson414
5Purdue Pharma LP377
6Medtronic PLC229
7Siemens AG198
8Novartis AG184
9University of California169
10Roche Holding AG161

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)11,028
2A61KMedicinal preparations9,656
3C07DHeterocyclic compounds6,541
4C07KPeptides1,357
5G01NInvestigating / analysing materials1,178
6A61LSterilising / disinfecting materials1,034
7C07CAcyclic and carbocyclic compounds1,017
8C08LPolymer compositions (blends)868
9C12NMicroorganisms, enzymes819
10Y02AClimate change adaptation618

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Synergistic compositions containing ketanserin1990Johnson and Johnson27
Process for the dehydrogenative dimerization and/or polymerization of organic compounds with active hydrogen atoms using perketals1986Arkema SA7
Process for preparing ketanserine19846
Cyclic perketals and their use for cross-linking high density polyethylene19816
Composition comprising ketanserin and L-carnitine or an alkanoyl L-carnitine for the treatment of CRPS2001Alfasigma SpA2

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
201622
201721
201816
201926
202018
202115
202218
202313
202414
20253

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Gitte M. KnudsenRigshospitalet26
2Bertil PerssonSahlgrenska University Hospital21
3Richard A. GlennonVirginia Commonwealth University Medical Center16
4Claus SvarerCopenhagen University Hospital11
5Lars H. PinborgRigshospitalet10
6Takafumi NagatomoNiigata University of Pharmacy and Medical and Life Sciences10
7Vibe G. FrøkjærRigshospitalet9
8Julie C. PriceUniversity of Pittsburgh8
9Jacek BorawskiMedical University of Białystok7
10Edward D. LevinDuke Medical Center7

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Ketanserin?

Ketanserin has the molecular formula C22H22FN3O3 and a molecular weight of 395.4344 g/mol.

Which companies hold the most patents involving Ketanserin?

The top patent assignees for Ketanserin-related compounds are Pfizer Inc with 722 patents, Boston Scientific Corp with 507 patents, and Bristol Myers Squibb Co with 446 patents.

What was the publication volume trend for Ketanserin research in recent years?

Paper publication activity on Ketanserin has remained modest in recent years, with 14 papers published in 2024 and 3 in 2025. The highest recent activity was 26 papers in 2019.

What are the primary research topics associated with Ketanserin in the literature?

Key research topics include its role as a selective ligand for serotonin2 receptor binding sites, its application in schizophrenia research related to serotonin-2 agonist action, effects on cortical 5-HT2A receptor-mediated signaling pathways, and its antagonist properties at 5-HT2 receptors.

What patent applications relate to therapeutic uses of Ketanserin?

Patents on Ketanserin include synergistic compositions containing Ketanserin filed by Johnson and Johnson in 1990, and a composition comprising Ketanserin and L-carnitine or alkanoyl L-carnitine for the treatment of CRPS filed by Alfasigma SpA in 2001.

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