Book a demo

Chemical intelligence powered by cypris.ai

Oxaprozin

3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid · also: Walix, Oxapro, Dayrun, Daypro, Deflam, Xopane

FormulaC18H15NO3
Mol. weight293.322
PubChem CID4614
InChIKeyOFPXSFXSNFPTHF-UHFFFAOYSA-N
SMILESC1=CC=C(C=C1)C2=C(OC(=N2)CCC(=O)O)C3=CC=CC=C3
55,757Patents
230Research papers
4,701Patents - last 3 years
8Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Merck Sharp & Dohme LLC1,389
2AbbVie Inc1,246
3Procter and Gamble Co739
4Purdue Pharma LP630
5Genentech Inc510
6F Hoffmann La Roche AG482
7Takeda Pharmaceutical Co Ltd467
8Pfizer Inc463
9Amgen Inc362
10Ono Pharmaceutical Co Ltd358

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

Visit Cypris

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)42,888
2A61KMedicinal preparations40,840
3C07DHeterocyclic compounds19,361
4C07KPeptides9,019
5Y02AClimate change adaptation4,246
6C07CAcyclic and carbocyclic compounds3,602
7C12NMicroorganisms, enzymes3,525
8G01NInvestigating / analysing materials3,099
9A61LSterilising / disinfecting materials2,749
10A61QCosmetics, personal care2,377

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

See Cypris in action

Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Potassium, sodium and tris oxaprozin salt pharmaceutical formulations2000GD Searle LLC9
Oxaprozin calcium salt1984John Wyeth and Brother Ltd7
Oxaprozin calcium salt pharmaceutical compositions1985John Wyeth and Brother Ltd6
Oxaprozin or closely related compound for the treatment and prevention of pruritus2006Astion Development A/S3
Oxaprozin and preparation technology thereof2012SHANDONG KERNEL AND HALL PHARMACEUTICAL INDUSTRY CO., LTD.2

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Drug-Induced Adverse Reactions2
2Inflammatory mediators and NSAID effects2
3Porphyrin Metabolism and Disorders2
4Computational Drug Discovery Methods1
5Drug-Induced Hepatotoxicity and Protection1
6Musculoskeletal pain and rehabilitation1

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

See Cypris in action

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Barry R. WalkerUniversity of Pennsylvania8
2Francesca MaestrelliUniversity of Florence6
3Hans W. RueliusUniversity of Pennsylvania6
4James IngleseNational Institutes of Health6
5Jerome A. HubsherPenn Center for AIDS Research5
6Ajit JadhavNational Center for Advancing Translational Sciences4
7Anton SimeonovNational Center for Advancing Translational Sciences4
8Daniel MerkGoethe University Frankfurt4
9Frank W. JanssenPenn Center for AIDS Research4
10Matthew D. HallNational Institutes of Health4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

See Cypris in action

The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical structure of Oxaprozin?

Oxaprozin has the canonical chemical name 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid with the molecular formula C18H15NO3 and a molecular weight of 293.322. Its InChI Key is OFPXSNFPTHF-UHFFFAOYSA-N.

Which pharmaceutical companies have been active in patenting inventions related to Oxaprozin?

Major assignees holding patents in this field include Merck Sharp & Dohme LLC with 1389 patents, AbbVie Inc with 1246 patents, Procter and Gamble Co with 739 patents, Purdue Pharma LP with 630 patents, and Genentech Inc with 510 patents. Early patent activity on Oxaprozin salt formulations was conducted by John Wyeth and Brother Ltd and GD Searle LLC.

What are some early patent examples for Oxaprozin formulations?

Notable patents include a 1984 patent on Oxaprozin calcium salt assigned to John Wyeth and Brother Ltd, a 1985 patent on Oxaprozin calcium salt pharmaceutical compositions also from John Wyeth and Brother Ltd, and a 2000 patent on potassium, sodium and tris oxaprozin salt pharmaceutical formulations assigned to GD Searle LLC.

What research topics are associated with Oxaprozin in the scientific literature?

Key research topics include inflammatory mediators and NSAID effects, with papers examining cyclooxygenase inhibition and reactive oxygen and nitrogen species scavenging activities. Drug-induced adverse reactions, porphyrin metabolism and disorders, drug-induced hepatotoxicity, and musculoskeletal pain and rehabilitation are also studied in relation to Oxaprozin and similar compounds.

What is the patent classification landscape for compounds like Oxaprozin?

The dominant CPC subclasses associated with Oxaprozin-related patents are A61P (pharmaceutical preparations) with 42,888 patents and A61K (pharmaceutical compositions) with 40,840 patents. Other significant subclasses include C07D (heterocyclic compounds) with 19,361 patents and C07K (peptides) with 9,019 patents, reflecting the broad scope of medicinal chemistry and drug development in this space.

Turn any compound into a complete chemical intelligence landscape

Go beyond static compound data. Cypris resolves identities, patents, papers, and commercial signals into one AI-powered view - so your team can move from a single chemical question to a complete R&D, IP, and market landscape.

Schedule a free trial