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Dapsone

4-(4-aminophenyl)sulfonylaniline · also: Aczone · Eporal · Udolac · Dapson · Tarimyl · Undolac

FormulaC12H12N2O2S
Mol. weight248.3
PubChem CID2955
InChIKeyMQJKPEGWNLWLTK-UHFFFAOYSA-N
SMILESC1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N
101,214Patents
5,280Research papers5,264 indexed in detail
8,916Patents - last 3 years
98Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Toray Industries Inc3,765
2Resonac Holdings Corp3,264
3Kaneka Corp1,630
4Sumitomo Bakelite Co Ltd1,588
5Nippon Kayaku Co Ltd1,263
6Saudi Arabian Oil Co1,203
7Fujifilm Holdings Corp1,116
8Nissan Chemical Corp1,073
9Mitsui Chemicals Inc960
10Toyobo Co Ltd933

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C08GPolymers from non-vinyl bonds (e.g. polyamides, polyesters)27,888
2C08LPolymer compositions (blends)23,986
3A61KMedicinal preparations21,740
4A61PTherapeutic activity (drug indications)19,725
5C08KPolymer compositions (additives)13,578
6C08JWorking-up of plastics12,022
7Y10TCross-reference (technical subjects)8,425
8C07DHeterocyclic compounds8,202
9C09DCoatings, paints, varnishes7,296
10B32BLayered products7,243

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Dapsone and promin for the treatment of dementia199629
COMBINATION OF DAPSONE WITH ADAPALENE2011AbbVie Inc18
DAPSONE TO TREAT ROSASCEA2009Tolmar Holding Inc13
Emulsifying composition containing dapsone200712
EMULSIVE COMPOSITION CONTAINING DAPSONE2005Tolmar Holding Inc10

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
201681
201783
201887
201985
202082
202163
202254
202343
202441
202514

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Michael D. ColemanAston University21
2Takashi HashimotoKurume University17
3R. J. W. ReesNational Institute for Medical Research17
4Brian GreenwoodMRC Unit the Gambia12
5S Balakrishnan12
6G RamuNational JALMA Institute for Leprosy & Other Mycobacterial Diseases12
7Paul FasalUnited States Public Health Service11
8J. M. H. PearsonCentral Leprosy Teaching & Research Institute10
9Pattyn10
10Charles C. ShepardUniversity of Hawaii System10

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Dapsone?

Dapsone has the molecular formula C12H12N2O2S and a molecular weight of 248.3 g/mol. Its canonical IUPAC name is 4-(4-aminophenyl)sulfonylaniline.

Which organizations hold the most patents related to Dapsone?

Toray Industries Inc leads with 3765 patents, followed by Resonac Holdings Corp with 3264 patents and Kaneka Corp with 1630 patents related to Dapsone.

What are the most prolific authors publishing research on Dapsone?

Michael D. Coleman from Aston University has published 21 papers on Dapsone, followed by Takashi Hashimoto from Kurume University and R. J. W. Rees from National Institute for Medical Research, each with 17 papers.

What patent applications have been filed for Dapsone formulations and combinations?

Notable patents include a combination of Dapsone with Adapalene filed by AbbVie Inc in 2011, an emulsifying composition containing Dapsone from Tolmar Holding Inc filed in 2005, and a patent on Dapsone for treating rosacea also from Tolmar Holding Inc filed in 2009.

How has the patent and paper publication volume changed over recent years?

Patent filings related to Dapsone peaked in 2023 with 4890 patents, declining to 4754 in 2024. Paper publications show a declining trend, with 81 papers in 2016 decreasing to 41 in 2024. In the last 3 years, there were 8916 patents and 98 papers published.

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