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Noradrop

4-(2-amino-1-hydroxyethyl)benzene-1,2-diol · also: dl-Arterenol, dl-Noradrenaline, xi-Norepinephrine, dl-Norepinephrine, Noradrenalin, dl-, Noradrenaline,(+)

FormulaC8H11NO3
Mol. weight169.18
PubChem CID951
InChIKeySFLSHLFXELFNJZ-UHFFFAOYSA-N
SMILESC1=CC(=C(C=C1C(CN)O)O)O
81,640Patents
88,141Research papers
3,465Patents - last 3 years
792Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Merck Sharp & Dohme LLC1,513
2Allergan Inc1,225
3Merck and Co Inc982
4F Hoffmann La Roche AG914
5Pfizer Inc758
6Eli Lilly and Co727
7Janssen Pharmaceutica NV618
8Dexcom Inc571
9Pfizer Corp SRL569
10Wyeth LLC514

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)52,297
2A61KMedicinal preparations44,417
3C07DHeterocyclic compounds26,243
4C07KPeptides7,831
5G01NInvestigating / analysing materials6,549
6C07CAcyclic and carbocyclic compounds6,083
7C12NMicroorganisms, enzymes5,220
8A61B4,240
9A61N2,945
10C12QMeasuring/testing involving enzymes2,935

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
PROCESS FOR PREPARATION OF (DL) -NOREPINEPHRINE ACID ADDITION SALT, A KEY INTERMEDIATE OF (R) - (-) - NOREPINEPHRINE2013DALVI, MAHESH BHAGOJI17

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Neuroscience and Neuropharmacology Research56
2Neurotransmitter Receptor Influence on Behavior51
3Heart Rate Variability and Autonomic Control47
4Receptor Mechanisms and Signaling45
5Adipose Tissue and Metabolism41
6Neuropeptides and Animal Physiology36
7Neuroendocrine regulation and behavior27
8Nitric Oxide and Endothelin Effects25
9Stress Responses and Cortisol24
10Diet and metabolism studies22

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Irwin J. KopinNational Institute of Mental Health127
2Kjell FuxéKarolinska Institutet86
3Klaus StarkeUniversity of Freiburg73
4Murray EslerBaker Heart and Diabetes Institute73
5David S. GoldsteinNational Institute of Neurological Disorders and Stroke62
6Gavin LambertBaker Heart and Diabetes Institute54
7Geoffrey BurnstockUniversity College London46
8Niels Juel ChristensenHerlev Hospital44
9Shigetoshi ChibaShinshu University42
10M. J. RandThe University of Melbourne40

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

TitleYearCited byTopic
Brown Adipose Tissue: Function and Physiological Significance20046428Adipokines, Inflammation, and Metabolic Diseases
AN INTEGRATIVE THEORY OF LOCUS COERULEUS-NOREPINEPHRINE FUNCTION: Adaptive Gain and Optimal Performance20054647Neurotransmitter Receptor Influence on Behavior
Stereotaxic Mapping of the Monoamine Pathways in the Rat Brain*19713819Neurotransmitter Receptor Influence on Behavior
A Systematic Method for Clinical Description and Classification of Personality Variants19873692Neurotransmitter Receptor Influence on Behavior
Stress and disorders of the stress system20093195Stress Responses and Cortisol

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical structure and molecular composition of Noradrop?

Noradrop has the IUPAC name 4-(2-amino-1-hydroxyethyl)benzene-1,2-diol with molecular formula C8H11NO3 and molecular weight 169.18. The InChI key is SFLSHLFXELFNJZ-UHFFFAOYSA-N. It is also known by several synonyms including dl-Noradrenaline and dl-Norepinephrine, reflecting its racemic composition.

Which companies hold the most patents related to this compound?

The leading patent assignees in the Noradrop space are Merck Sharp & Dohme LLC with 1513 patents, Allergan Inc with 1225 patents, Merck and Co Inc with 982 patents, F Hoffmann La Roche AG with 914 patents, and Pfizer Inc with 758 patents.

What are the main research topics associated with Noradrop in the scientific literature?

The primary research topics include Neuroscience and Neuropharmacology Research, Neurotransmitter Receptor Influence on Behavior, Heart Rate Variability and Autonomic Control, Receptor Mechanisms and Signaling, and Adipose Tissue and Metabolism. Additional topics cover Neuropeptides and Animal Physiology, Neuroendocrine regulation and behavior, Nitric Oxide and Endothelin Effects, and Stress Responses and Cortisol.

Which researchers have published the most papers on topics related to this compound?

The most prolific authors include Irwin J. Kopin from the National Institute of Mental Health with 127 papers, Kjell Fuxé from Karolinska Institutet with 86 papers, Klaus Starke from University of Freiburg with 73 papers, and Murray Esler from Baker Heart and Diabetes Institute with 73 papers.

What patent classifications are most commonly associated with this compound?

The most prevalent CPC subclasses for patents related to Noradrop are A61P (Pharmaceutical preparations) with 52297 patents, A61K (Medicinal preparations) with 44417 patents, C07D (Heterocyclic compounds) with 26243 patents, C07K (Peptide compounds) with 7831 patents, and G01N (Investigating or analyzing materials) with 6549 patents.

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