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Carprofen

2-(6-chloro-9H-carbazol-2-yl)propanoic acid · also: Imadyl, Rovera, OstiFen, Quellin, Ridamyl, Levafen

FormulaC15H12ClNO2
Mol. weight273.716
PubChem CID2581
InChIKeyPUXBGTOOZJQSKH-UHFFFAOYSA-N
SMILESCC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O
22,866Patents
536Research papers
1,958Patents - last 3 years
17Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Ionis Pharmaceuticals Inc1,105
2Procter and Gamble Co510
3Purdue Pharma LP499
4Syngenta Participations AG368
5Boehringer Ingelheim International GmbH290
6Merck Sharp & Dohme LLC276
7Bayer Pharma AG263
8Boehringer Ingelheim Animal Health USA Inc251
9Abbott Cardiovascular Systems Inc243
10Kenvue Brands LLC242

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)16,603
2A61KMedicinal preparations16,406
3C07DHeterocyclic compounds7,084
4C12NMicroorganisms, enzymes3,389
5C07KPeptides3,208
6C07CAcyclic and carbocyclic compounds1,563
7A61LSterilising / disinfecting materials1,337
8Y02AClimate change adaptation1,280
9A61QCosmetics, personal care1,212
10G01NInvestigating / analysing materials1,146

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in mammals using carprofen and derivatives2003Pfizer Corp SRL42
Use of carprofen and derivatives therof for treating or preventing articular degeneration2000Pfizer Products Inc5
A kind of method that use biological enzyme stereoselectivity splits Carprofen enantiomer2017HUNAN TECHNOLOGY COLLEGE3
Synthesis of carprofen2009SHANDONG FANGXING SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD.3
STABLE CARPROFEN COMPOSITION2004Jurox Pty Ltd3

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Inflammatory mediators and NSAID effects12
2Veterinary Pharmacology and Anesthesia6
3Animal Behavior and Welfare Studies1
4Animal Nutrition and Physiology1
5Biosimilars and Bioanalytical Methods1
6Bone health and treatments1
7Cancer, Stress, Anesthesia, and Immune Response1
8Helicobacter pylori-related gastroenterology studies1
9Meat and Animal Product Quality1
10Microfluidic and Capillary Electrophoresis Applications1

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1A. E. Waterman‐PearsonUniversity of Bristol9
2J. V. RoughanNewcastle University7
3P. LeesRoyal Veterinary College7
4A. NolanUniversity of Glasgow6
5B. LudwigRoche (Switzerland)6
6Anton SimeonovNational Center for Advancing Translational Sciences5
7Ajit JadhavNational Center for Advancing Translational Sciences4
8B. Duncan X. LascellesUniversity of Bristol4
9Caroline LeeCommonwealth Scientific and Industrial Research Organisation4
10Dorothy Cimino BrownUniversity of Pennsylvania4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular structure and formula of carprofen?

Carprofen has the canonical name 2-(6-chloro-9H-carbazol-2-yl)propanoic acid with the molecular formula C15H12ClNO2 and a molecular weight of 273.716. Its InChI key is PUXBGTOOZJQSKH-UHFFFAOYSA-N.

What are the common commercial and brand names for carprofen?

Carprofen is marketed under numerous brand names including Rimadyl, Vetprofen, Novox Chewable, Imadyl, Rovera, OstiFen, Quellin, Ridamyl, Levafen, Norocarp, Carprieve, Carprodyl, Belprofen, and Carpaquin, among others.

What are the primary research topics associated with carprofen in published literature?

The major research topics include inflammatory mediators and NSAID effects, veterinary pharmacology and anesthesia, pain mechanisms and treatments, animal nutrition and physiology, and anesthesia and pain management. Notable papers address postoperative pain evaluation in dogs, analgesic effects in lame broiler chickens, and carprofen efficacy in dogs undergoing surgery.

What patent applications cover carprofen's medical uses?

Patents include applications on treating or preventing early-stage articular cartilage and subchondral bone degeneration using carprofen and derivatives, methods for articular degeneration prevention, synthesis of carprofen, enzymatic separation of carprofen enantiomers, and stable carprofen compositions. These patents span from 2000 to 2017 and come from organizations including Pfizer, Jurox Pty Ltd, Shandong Fangxing Science and Technology Development Co., Ltd., and Hunan Technology College.

How has research and patent activity for carprofen trended in recent years?

Patent activity reached peaks of 1,228 in 2017 and 1,187 in 2016, with a general decline to 588 in 2025. Paper publication has shown variability, peaking at 19 papers in 2020 and declining to 5 papers in 2024. Over the last three years, 1,958 patents and 17 papers have been published related to carprofen.

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