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Carprofen

2-(6-chloro-9H-carbazol-2-yl)propanoic acid · also: Imadyl · Rovera · Ridamyl · Quellin · Levafen · Rimadyl

FormulaC15H12ClNO2
Mol. weight273.716
PubChem CID2581
InChIKeyPUXBGTOOZJQSKH-UHFFFAOYSA-N
SMILESCC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O
22,866Patents
536Research papers535 indexed in detail
1,853Patents - last 3 years
17Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Ionis Pharmaceuticals Inc1,105
2Merck and Co Inc704
3Sinochem Holdings Corp Ltd617
4C.H. Boehringer Sohn AG and Co KG608
5Pfizer Inc572
6Procter and Gamble Co520
7Purdue Pharma LP519
8Bayer AG420
9Amgen Inc415
10Bristol Myers Squibb Co345

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)16,604
2A61KMedicinal preparations16,410
3C07DHeterocyclic compounds7,084
4C12NMicroorganisms, enzymes3,389
5C07KPeptides3,209
6C07CAcyclic and carbocyclic compounds1,563
7A61LSterilising / disinfecting materials1,337
8Y02AClimate change adaptation1,280
9A61QCosmetics, personal care1,212
10G01NInvestigating / analysing materials1,146

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in mammals using carprofen and derivatives2003Pfizer Inc42
Use of carprofen and derivatives therof for treating or preventing articular degeneration2000Pfizer Inc5
A kind of method that use biological enzyme stereoselectivity splits Carprofen enantiomer20173
Synthesis of carprofen20093
STABLE CARPROFEN COMPOSITION2004Zoetis Inc3

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
201613
201715
201812
201916
202019
20218
202213
20239
20245
20253

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1P. LeesRoyal Veterinary College17
2Miguel A. MirandaUniversitat Politècnica de València8
3Quintin McKellarUniversity of Glasgow8
4B. LudwigRoche (Switzerland)6
5Paul FlecknellNewcastle University6
6Francisco BoscáUniversitat Politècnica de València5
7Kristen M. MessengerNorth Carolina State University5
8Lon V. KendallColorado State University5
9Matthew D. HallNational Institutes of Health5
10Dorothy Cimino BrownUniversity of Pennsylvania4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular structure and formula of carprofen?

Carprofen has the canonical name 2-(6-chloro-9H-carbazol-2-yl)propanoic acid with molecular formula C15H12ClNO2 and molecular weight 273.716. Its InChI Key is PUXBGTOOZJQSKH-UHFFFAOYSA-N.

Which companies hold the most patents related to carprofen?

The leading patent assignees for carprofen-related inventions are Ionis Pharmaceuticals Inc with 1105 patents, Merck and Co Inc with 704 patents, and Sinochem Holdings Corp Ltd with 617 patents. Pfizer Inc holds 572 patents and has assigned key carprofen patents including treatments for articular degeneration.

What are the main research topics in published literature on carprofen?

Published research on carprofen spans veterinary pharmacology and anesthesia, pain mechanisms and treatments, and animal nutrition and physiology. Key studies include pain evaluation scales for dogs, the drug's effects on lameness in broiler chickens, efficacy in preventing postoperative pain in dogs, and self-selection behavior by lame animals.

Who are the most prolific authors publishing on carprofen?

P. Lees from Royal Veterinary College is the leading author with 17 papers on carprofen. Other prolific contributors include Miguel A. Miranda and Francisco Boscá from Universitat Politècnica de València, and Quintin McKellar from University of Glasgow, each with 8 papers.

What is the recent publication and patent trend for carprofen?

Patent filings for carprofen declined from a peak of 1228 patents in 2017 to 588 patents in 2025. Paper publications have been limited in recent years, with only 3 papers in 2025 and 5 in 2024, compared to earlier years averaging 12-19 papers annually.

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