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Cetirizine

2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid · also: Humex, Setir, Ziptek, Virlix, Zyrlex, Zirtek

FormulaC21H25ClN2O3
Mol. weight388.892
PubChem CID2678
InChIKeyZKLPARSLTMPFCP-UHFFFAOYSA-N
SMILESC1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
36,542Patents
1,874Research papers
2,703Patents - last 3 years
59Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1AstraZeneca AB1,110
2Merck Sharp & Dohme LLC1,096
3Novartis AG1,052
4Boehringer Ingelheim International GmbH867
5Glaxo Group Ltd757
6Procter and Gamble Co512
7Massachusetts Institute of Technology504
8Kenvue Brands LLC425
9AbbVie Inc419
10Ono Pharmaceutical Co Ltd355

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)25,867
2A61KMedicinal preparations25,376
3C07DHeterocyclic compounds13,716
4C07KPeptides3,597
5C12NMicroorganisms, enzymes2,297
6A61MDevices for introducing media into the body2,153
7Y02AClimate change adaptation1,971
8C07CAcyclic and carbocyclic compounds1,930
9G01NInvestigating / analysing materials1,390
10A61QCosmetics, personal care1,200

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Combination dosage form comprising cetirizine and pseudoephedrine2001Kenvue Brands LLC60
Methods and compositions using cetirizine in combination with leukotriene inhibitors or decongestants2002Sumitomo Pharma America Inc45
Solid, rapidly disintegrating cetirizine formulations2001Meda Pharma GmbH and Co KG43
CETIRIZINE-CONTAINING COMPOSITION FOR ANTIALLERGIC EYE DROP AND NASAL DROP1994Senju Pharmaceutical Co Ltd40
Methods for treating allergic disorders using optically pure (-) cetirizine1997Sumitomo Pharma America Inc39

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Allergic Rhinitis and Sensitization22
2Asthma and respiratory diseases7
3Urticaria and Related Conditions6
4Dermatology and Skin Diseases4
5Analytical Chemistry and Chromatography3
6Analytical Methods in Pharmaceuticals3
7Drug-Induced Adverse Reactions3
8Cardiac electrophysiology and arrhythmias2
9Drug Transport and Resistance Mechanisms2
10Mast cells and histamine2

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1J.‐P. RihouxUCB Pharma (Belgium)18
2Giorgio CiprandiOspedale Policlinico San Martino11
3F. Estelle R. SimonsUniversity of Manitoba9
4Giorgio Walter CanonicaUniversity of Genoa10
5Bernard BurtinUCB Pharma (Belgium)9
6Garry M. WalshUniversity of Aberdeen6
7Andrew M. WilsonUniversity of Dundee5
8Annemiek VermeerenMaastricht University5
9Antonio ValeroHospital Clínic de Barcelona5
10Ashok PurohitInserm5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of cetirizine?

Cetirizine has the molecular formula C21H25ClN2O3 and a molecular weight of 388.892 g/mol.

Which organizations hold the most patents related to cetirizine?

The leading patent holders in the cetirizine field are AstraZeneca AB with 1110 patents, Merck Sharp & Dohme LLC with 1096 patents, and Novartis AG with 1052 patents.

What are the main research topics associated with cetirizine?

The primary research topics are Allergic Rhinitis and Sensitization with 22 papers, Asthma and respiratory diseases with 7 papers, and Urticaria and Related Conditions with 6 papers.

What formulation innovations have been patented for cetirizine?

Notable patented innovations include solid, rapidly disintegrating cetirizine formulations, combination dosage forms with pseudoephedrine and decongestants, and compositions for antiallergic eye drop and nasal drop applications.

Who are the most prolific authors publishing on cetirizine research?

The leading researchers include J.‐P. Rihoux from UCB Pharma (Belgium) with 18 papers, Giorgio Ciprandi from Ospedale Policlinico San Martino with 11 papers, and Giorgio Walter Canonica from University of Genoa with 10 papers.

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