Book a demo

Chemical intelligence powered by cypris.ai

Milrila

6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile · also: Primacor, Corotrop, Milrinona, Corotrope, milrinone, Milrila-K

FormulaC12H9N3O
Mol. weight211.224
PubChem CID4197
InChIKeyPZRHRDRVRGEVNW-UHFFFAOYSA-N
SMILESCC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2
22,562Patents
2,142Research papers
1,224Patents - last 3 years
73Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Dow Global Technologies LLC1,309
2Merck Sharp & Dohme LLC947
3Novartis AG621
43M Innovative Properties Co477
53M Co392
6Alza Corp323
7Topgolf Callaway Brands Corp291
8Bayer Pharma AG263
9Vertex Pharmaceuticals Inc237
10Merck and Co Inc236

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

Visit Cypris

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)11,322
2A61KMedicinal preparations10,653
3C07DHeterocyclic compounds5,706
4C08LPolymer compositions (blends)2,960
5Y10TCross-reference (technical subjects)2,644
6B32BLayered products2,031
7C07KPeptides1,428
8C08JWorking-up of plastics1,225
9C12NMicroorganisms, enzymes1,220
10C08KPolymer compositions (additives)1,170

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

See Cypris in action

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Heart Failure Treatment and Management19
2Pulmonary Hypertension Research and Treatments8
3Phosphodiesterase function and regulation7
4Cardiac electrophysiology and arrhythmias5
5Congenital Heart Disease Studies4
6Cardiovascular Function and Risk Factors2
7Heart Rate Variability and Autonomic Control2
8Hemodynamic Monitoring and Therapy2
9Ion channel regulation and function2
10Mechanical Circulatory Support Devices2

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

See Cypris in action

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1André DenaultMontreal Heart Institute21
2Wilson S. ColucciBrigham and Women's Hospital12
3A. J. PorsiusUtrecht University9
4Alexandre MebazaaHôpital Lariboisière8
5A. FarahSterling Research Group (United States)7
6Afif El‐KhuffashRotunda Hospital7
7Adawia A. AlousiSterling Research Group (United States)6
8Akihiro NarimatsuMitsubishi Group (Japan)6
9Annik FortierUniversité de Montréal3
10Christopher M. O’ConnorClinical Research Institute4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

See Cypris in action

The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical composition and molecular weight of Milrila?

Milrila has the molecular formula C12H9N3O with a molecular weight of 211.224. Its canonical chemical name is 6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile, and it is also known by several synonyms including milrinone, Primacor, and Corotrop.

Which organizations hold the most patents related to this compound?

The leading patent assignees in this field are Dow Global Technologies LLC with 1309 patents, Merck Sharp and Dohme LLC with 947 patents, and Novartis AG with 621 patents.

What are the primary research topics associated with this compound?

The dominant research topic is Heart Failure Treatment and Management with 19 papers, followed by Pulmonary Hypertension Research and Treatments with 8 papers. Other notable topics include Cardiac electrophysiology and arrhythmias, Congenital Heart Disease Studies, and Phosphodiesterase function and regulation.

Who are the most prolific authors publishing on this compound?

André Denault from Montreal Heart Institute leads with 21 papers, followed by Wilson S. Colucci from Brigham and Women's Hospital with 12 papers, and A. J. Porsius from Utrecht University with 9 papers.

What are the highest-impact publications on this compound?

The most cited paper is "Effect of Oral Milrinone on Mortality in Severe Chronic Heart Failure" from 1991 with 2231 citations, followed by "Short-term Intravenous Milrinone for Acute Exacerbation of Chronic Heart Failure" from 2002 with 1170 citations. Both papers focus on Heart Failure Treatment and Management.

Turn any compound into a complete chemical intelligence landscape

Go beyond static compound data. Cypris resolves identities, patents, papers, and commercial signals into one AI-powered view - so your team can move from a single chemical question to a complete R&D, IP, and market landscape.

Schedule a free trial