Who owns the IP
The organizations most actively patenting around this compound, ranked by referenced patent volume.
| # | Assignee | Patents |
|---|---|---|
| 1 | Pfizer Inc | 2,053 |
| 2 | Merck and Co Inc | 1,513 |
| 3 | Dexcom Inc | 1,260 |
| 4 | GSK PLC | 1,191 |
| 5 | Roche Holding AG | 974 |
| 6 | Johnson and Johnson | 850 |
| 7 | Organon and Co | 680 |
| 8 | NTG Nordic Transport Group AS | 624 |
| 9 | AbbVie Inc | 589 |
| 10 | Esteve Healthcare SL | 481 |
Explore the full landscape
This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.
Visit CyprisWhere innovation is concentrated
Patent classifications ranked by volume reveal the technical domains with the most active filing.
| # | Code | Area | Patents |
|---|---|---|---|
| 1 | A61P | Therapeutic activity (drug indications) | 36,715 |
| 2 | A61K | Medicinal preparations | 32,506 |
| 3 | C07D | Heterocyclic compounds | 20,710 |
| 4 | G01N | Investigating / analysing materials | 8,566 |
| 5 | C07K | Peptides | 4,639 |
| 6 | A61B | 4,284 | |
| 7 | Y02A | Climate change adaptation | 3,493 |
| 8 | C12N | Microorganisms, enzymes | 3,478 |
| 9 | C07C | Acyclic and carbocyclic compounds | 3,256 |
| 10 | A61M | Devices for introducing media into the body | 2,555 |
AI mapped opportunity space
This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.
See Cypris in actionRepresentative patents
The filings that best characterise the patent activity around this compound, most-referenced first.
| Title | Year | Assignee | Cited by |
|---|---|---|---|
| Treatment for cocaine abuse | 1991 | 250 | |
| Treatment of cocaine addiction | 1993 | 102 | |
| COCAINE RECEPTOR BINDING LIGANDS | 1992 | 77 | |
| Cocaine receptor binding ligands | 1995 | Government of the United States of America | 69 |
| Non-oxo-carbonyl containing benzoyl ecgonine and cocaine compounds polypeptide and derivatives thereof | 1977 | Siemens AG | 64 |
How research activity has moved
Papers published per year for this compound, over the last decade of indexed records.
| Year | Papers |
|---|---|
| 2016 | 585 |
| 2017 | 502 |
| 2018 | 452 |
| 2019 | 474 |
| 2020 | 464 |
| 2021 | 493 |
| 2022 | 489 |
| 2023 | 457 |
| 2024 | 288 |
| 2025 | 105 |
Who's driving the science
The most-published authors working with this compound, alongside their primary affiliations.
| # | Author | Affiliation | Papers |
|---|---|---|---|
| 1 | Peter W. Kalivas | Medical University of South Carolina | 133 |
| 2 | Eric J. Nestler | Icahn School of Medicine at Mount Sinai | 132 |
| 3 | Thomas R. Kosten | Yale University | 130 |
| 4 | Nora D. Volkow | National Institute on Drug Abuse | 125 |
| 5 | Jonathan L. Katz | National Institute on Drug Abuse | 97 |
| 6 | Michael A. Nader | Wake Forest University | 77 |
| 7 | Maarten E. A. Reith | Illinois College | 76 |
| 8 | Mary Jeanne Kreek | Rockefeller University | 75 |
| 9 | George F. Koob | Scripps Research Institute | 75 |
| 10 | Małgorzata Filip | Maj Institute of Pharmacology | 69 |
Research leaders
This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.
See Cypris in actionThe literature that defines it
The most-cited papers anchoring the scientific record for this compound.
| Title | Year | Cited by | Topic |
|---|---|---|---|
| Guía de práctica clínica para el tratamiento de los tumores intracraneales | 2009 | 5287 | Neuroblastoma Research and Treatments |
| The 2007 WHO Classification of Tumours of the Central Nervous System | 2007 | 4570 | Glioma Diagnosis and Treatment |
| The fifth edition of the addiction severity index | 1992 | 4274 | Substance Abuse Treatment and Outcomes |
| The self-medication hypothesis of addictive disorders: focus on heroin and cocaine dependence | 1985 | 2526 | Schizophrenia research and treatment |
| Natural Antibiotic Resistance and Contamination by Antibiotic Resistance Determinants: The Two Ages in the Evolution of Resistance to Antimicrobials | 2012 | 2108 | Antibiotic Resistance in Bacteria |
Frequently asked questions
Common questions about this compound's patent and research landscape, answered from the underlying data.
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