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methyl (1R,2R,3S,5S)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate · also: Flake, sugar, Candy, Snort, Cecil, Crack

FormulaC17H21NO4
Mol. weight303.358
PubChem CID446220
InChIKeyZPUCINDJVBIVPJ-LJISPDSOSA-N
SMILESCN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)OC(=O)C3=CC=CC=C3)C(=O)OC
65,349Patents
36,219Research papers
5,813Patents - last 3 years
849Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Dexcom Inc1,260
2Merck Sharp & Dohme LLC1,210
3Pfizer Inc837
4Glaxo Group Ltd828
5F Hoffmann La Roche AG785
6Organon Pharma UK Ltd649
7Pfizer Corp SRL639
8Janssen Pharmaceutica NV627
9NTG Nordic Transport Group AS586
10Pfizer Products Inc564

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)36,703
2A61KMedicinal preparations32,468
3C07DHeterocyclic compounds20,710
4G01NInvestigating / analysing materials8,564
5C07KPeptides4,639
6A61B4,284
7Y02AClimate change adaptation3,492
8C12NMicroorganisms, enzymes3,474
9C07CAcyclic and carbocyclic compounds3,246
10A61MDevices for introducing media into the body2,555

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Sensors for sugars and other metal binding analytes2000California Institute of Technology466
Combination of sugars with animo acids and other drugs1995Naito, Albert127
SUSTAINED LOCAL ANESTHETIC COMPOSITION CONTAINING PREFERABLY A SUGAR ESTER SUCH AS SAIB2006Durect Corp23
SWEETNESS ENHANCED SUGARS AND SUGAR LIKE PRODUCTS2012ABBA PHARMA LIMITED20
Message processing method and device based on Snort rule set2011DAWNING INFORMATION INDUSTRY (BEIJING) CO., LTD.12

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Neurotransmitter Receptor Influence on Behavior243
2Forensic Toxicology and Drug Analysis114
3Prenatal Substance Exposure Effects65
4Substance Abuse Treatment and Outcomes64
5Neuroscience and Neuropharmacology Research33
6Opioid Use Disorder Treatment24
7Cannabis and Cannabinoid Research20
8HIV, Drug Use, Sexual Risk17
9Attention Deficit Hyperactivity Disorder15
10HIV Research and Treatment11

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Eric J. NestlerIcahn School of Medicine at Mount Sinai146
2Peter W. KalivasMedical University of South Carolina141
3Thomas R. KostenYale University139
4Nora D. VolkowBrookhaven National Laboratory130
5Amy Hauck NewmanNational Institute on Drug Abuse111
6George F. KoobScripps Research Institute98
7Jonathan L. KatzNational Institute on Drug Abuse96
8F. Ivy CarrollRTI International95
9Mary Jeanne KreekRockefeller University79
10Michael A. NaderWake Forest University77

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of this compound?

The compound has a molecular formula of C17H21NO4 and a molecular weight of 303.358 g/mol.

Which research topics are most frequently associated with publications on this compound?

The most prominent research topics are Neurotransmitter Receptor Influence on Behavior with 209 papers, Forensic Toxicology and Drug Analysis with 92 papers, and Prenatal Substance Exposure Effects with 61 papers.

Who are the leading authors publishing research on this compound?

The most prolific authors include Eric J. Nestler from Icahn School of Medicine at Mount Sinai with 146 papers, Peter W. Kalivas from Medical University of South Carolina with 141 papers, and Thomas R. Kosten from Yale University with 139 papers.

What patent classification codes dominate the patent landscape for this compound?

The most prevalent CPC subclasses are A61P with 36,696 patents, A61K with 32,468 patents, and C07D with 20,710 patents, reflecting strong activity in pharmaceutical and chemical synthesis domains.

How has research publication activity trended in recent years?

Paper publications peaked at 580 in 2016, then generally declined with 285 papers in 2024 and 105 papers in 2025, showing a significant downward trend in recent years.

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