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Tizanidine

5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine · also: Ternelin · Sirdalud · Zanaflex · Tizanidina · Tizanidinum · Sirdalud (TN)

FormulaC9H8ClN5S
Mol. weight253.708
PubChem CID5487
InChIKeyXFYDIVBRZNQMJC-UHFFFAOYSA-N
SMILESC1CN=C(N1)NC2=C(C=CC3=NSN=C32)Cl
13,550Patents
597Research papers595 indexed in detail
960Patents - last 3 years
25Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1AbbVie Inc1,074
2Bristol Myers Squibb Co461
3Pfizer Inc274
4Takeda Pharmaceutical Co Ltd263
5Purdue Pharma LP208
6Medtronic PLC203
7Novartis AG191
8Abbott Laboratories183
9Emory University148
10Biogen Inc143

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations10,800
2A61PTherapeutic activity (drug indications)10,150
3C07DHeterocyclic compounds3,569
4C07KPeptides2,207
5Y02AClimate change adaptation1,435
6C12NMicroorganisms, enzymes911
7G01NInvestigating / analysing materials808
8A61MDevices for introducing media into the body689
9C07CAcyclic and carbocyclic compounds445
10A61LSterilising / disinfecting materials415

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Method of reducing somnolence in patients treated with tizanidine2002Acorda Therapeutics Inc36
TIZANIDINE SUCCINATE SALT FORMS AND METHODS OF MAKING AND USING THE SAME2008Johnson and Johnson17
A METHOD FOR THE PREPARATION OF TIZANIDINE HYDROCHLORIDE201013
Novel use of tizanidine or its derivatives200711
Green new process for preparing tizanidine hydrochloride201110

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
201611
201710
201818
201917
202012
20218
202211
202312
202410
20253

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Janne T. BackmanUniversity of Helsinki11
2Kenji MomoUniversity of Tsukuba6
3Pertti J. NeuvonenUniversity of Helsinki6
4Mitsuo TanabeNagoya City University5
5Matthew D. HallNational Institutes of Health5
6Marika T. GranforsUniversity of Helsinki5
7Cynthia V. DillsNorthwestern University3
8Kelli M. WilsonNational Center for Advancing Translational Sciences3
9L GrovesAthena Group (United States)3
10Agostino PalmeriUniversity of Fribourg3

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of tizanidine?

Tizanidine has the molecular formula C9H8ClN5S and a molecular weight of 253.708 g/mol. Its canonical IUPAC name is 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine.

Which pharmaceutical companies hold the most patents related to tizanidine?

The leading patent assignees for tizanidine are AbbVie Inc with 1,074 patents, Bristol Myers Squibb Co with 461 patents, and Pfizer Inc with 274 patents. Other significant holders include Takeda Pharmaceutical Co Ltd with 263 patents and Purdue Pharma LP with 208 patents.

What are some commercial brand names for tizanidine?

Tizanidine is marketed under several brand names including Zanaflex, Sirdalud, and Ternelin.

Who are the most prolific authors publishing research on tizanidine?

The most active researchers publishing on tizanidine include Janne T. Backman from the University of Helsinki with 11 papers, Kenji Momo from the University of Tsukuba with 6 papers, and Pertti J. Neuvonen from the University of Helsinki with 6 papers.

What are the main patent application areas for tizanidine-related inventions?

The primary CPC subclasses associated with tizanidine patents are A61K (pharmaceutical preparations) with 10,800 patents, A61P (specific therapeutic activity of chemical compounds) with 10,150 patents, and C07D (heterocyclic compounds) with 3,569 patents.

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