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Zatosetron maleate

(Z)-but-2-enedioic acid;5-chloro-2,2-dimethyl-N-[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]-3H-1-benzofuran-7-carboxamide · also: Zatosetronmaleat, LY277359 maleate, LY-277359 maleate, LY 277359 maleate, Zatosetron (maleate), Zatosetron maleate (USAN)

FormulaC23H29ClN2O6
Mol. weight464.943
PubChem CID6918153
InChIKeyHAFQATMFFHYNPN-BSLJCGBVSA-N
SMILESCC1(CC2=C(O1)C(=CC(=C2)Cl)C(=O)NC3C[C@H]4CC[C@@H](C3)N4C)C.C(=C\C(=O)O)\C(=O)O
139Patents
22Research papers
11Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Aquestive Therapeutics Inc24
2The University of Texas System19
3University of Alabama at Birmingham10
4The University of Texas at Austin9
5American Regent Inc8
6Eli Lilly and Co6
7Ascendis Pharma AS5
8Scripps Research Institute5
9University of Alabama5
10Celanese EVA Performance Polymers Inc4

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations120
2A61PTherapeutic activity (drug indications)76
3A61MDevices for introducing media into the body27
4C07DHeterocyclic compounds17
5Y02AClimate change adaptation16
6Y10TCross-reference (technical subjects)15
7A01NPreservation of bodies; biocides; pest repellents14
8C08LPolymer compositions (blends)14
9B81B11
10B81C11

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Cancer Treatment and Pharmacology1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Charles R. AshbyStony Brook University2
2Marlene L. CohenEli Lilly (United States)4
3J. S. GiddaEli Lilly (United States)3
4Rex Y. WangStony Brook University2
5A.M. BendeleEli Lilly (United States)2
6Barbara J. RingEli Lilly (United States)2
7C. John ParliEli Lilly (United States)2
8David W. RobertsonEli Lilly (United States)2
9NULL AUTHOR_ID2
10Steven WrightonEli Lilly (United States)2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of zatosetron maleate?

Zatosetron maleate has the molecular formula C23H29ClN2O6 and a molecular weight of 464.943 g/mol.

Which organizations hold the most patents related to zatosetron maleate?

The leading patent assignees for zatosetron maleate are Aquestive Therapeutics Inc with 24 patents, The University of Texas System with 19 patents, and University of Alabama at Birmingham with 10 patents.

What are the primary research topics covered in zatosetron maleate publications?

Published research on zatosetron maleate covers several key areas including pharmacogenetics and drug metabolism, pain mechanisms and treatments, gastrointestinal motility and disorders, and schizophrenia research and treatment. The compound is specifically characterized as a potent and selective 5-HT3 receptor antagonist without gastroprokinetic activity.

How many patents and papers exist in the current database for zatosetron maleate?

There are 139 total patents and 22 papers in the database related to zatosetron maleate. In the last 3 years, there were 11 new patents, though no new papers were added during that period.

What intellectual property classifications are most common for zatosetron maleate patents?

The most prevalent CPC subclasses are A61K (pharmaceutical preparations) with 120 patents, A61P (specific therapeutic activity of chemical compounds) with 76 patents, and A61M (devices for introducing media into the body) with 27 patents.

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