Who owns the IP
The organizations most actively patenting around this compound, ranked by referenced patent volume.
| # | Assignee | Patents |
|---|---|---|
| 1 | Gilead Sciences Inc | 101 |
| 2 | Clearside Biomedical Inc | 67 |
| 3 | Senju Pharmaceutical Co Ltd | 58 |
| 4 | Institució Catalana de Recerca i Estudis Avançats | 43 |
| 5 | UVA Licensing and Ventures Group | 37 |
| 6 | Genentech Inc | 26 |
| 7 | Rohto Pharmaceutical Co Ltd | 23 |
| 8 | Alcon Inc | 21 |
| 9 | Ascendis Pharma AS | 21 |
| 10 | Kala Bio Inc | 20 |
Explore the full landscape
This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.
Visit CyprisWhere innovation is concentrated
Patent classifications ranked by volume reveal the technical domains with the most active filing.
| # | Code | Area | Patents |
|---|---|---|---|
| 1 | A61K | Medicinal preparations | 969 |
| 2 | A61P | Therapeutic activity (drug indications) | 890 |
| 3 | C07K | Peptides | 244 |
| 4 | C07D | Heterocyclic compounds | 218 |
| 5 | G01N | Investigating / analysing materials | 162 |
| 6 | C12Q | Measuring/testing involving enzymes | 125 |
| 7 | A61M | Devices for introducing media into the body | 94 |
| 8 | A61F | 85 | |
| 9 | C07C | Acyclic and carbocyclic compounds | 85 |
| 10 | C12N | Microorganisms, enzymes | 62 |
AI mapped opportunity space
This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.
See Cypris in actionMost-cited patents
Patents ranked by forward citations reveal the foundational inventions the field continues to build on.
| Title | Year | Assignee | Cited by |
|---|---|---|---|
| Gel for eye containing bromfenac sodium hydrate and preparation thereof | 2008 | WAN LIUYI | 6 |
| Bromfenac sodium hydrate eye drops and preparation method thereof | 2013 | LOU FEI | 4 |
| A kind of pharmaceutical aqueous eye drops and preparation method thereof containing bromfenac sodium hydrate | 2018 | Wuhan Leadpharm Technology Co., Ltd. | 3 |
| A kind of bromfenac sodium hydrate thermosensitive type situ-gel eye drop and preparation method thereof | 2016 | Guangzhou Ren Heng Pharmaceutical Technology Co., Ltd | 3 |
| Gel for eye containing bromfenac sodium hydrate and preparation thereof | 2013 | WEN GUANGHUI | 0 |
Where research is gaining momentum
Research themes ranked by publication activity show where scientific interest is accelerating around this compound.
| # | Research topic | Papers |
|---|---|---|
| 1 | Inflammatory mediators and NSAID effects | 3 |
| 2 | Coagulation, Bradykinin, Polyphosphates, and Angioedema | 2 |
| 3 | Anesthesia and Pain Management | 1 |
| 4 | Drug-Induced Hepatotoxicity and Protection | 1 |
| 5 | Glaucoma and retinal disorders | 1 |
| 6 | Ocular Surface and Contact Lens | 1 |
| 7 | Retinal Diseases and Treatments | 1 |
Technology trend analysis
Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.
See Cypris in actionWho's driving the science
The most-published authors working with this compound, alongside their primary affiliations.
| # | Author | Affiliation | Papers |
|---|---|---|---|
| 1 | James A. Gow | Spectrum Pharmaceuticals (United States) | 7 |
| 2 | L. David Waterbury | Emergent BioSolutions (Canada) | 6 |
| 3 | Frank A. Bucci | Bucci Laser Vision Institute | 5 |
| 4 | Joan Korth‐Bradley | Women's Health Research Institute | 5 |
| 5 | Sheryl DeCleene | Women's Health Research Institute | 5 |
| 6 | James A. Forbes | Johns Hopkins University | 4 |
| 7 | Nina R. Shah | 2 | |
| 8 | Timothy R. McNamara | Spectrum Pharmaceuticals (United States) | 4 |
| 9 | William H. Cevallos | Women's Health Research Institute | 4 |
| 10 | Curtis R. Kelly | Alcon (United States) | 3 |
Research leaders
This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.
See Cypris in actionThe literature that defines it
The most-cited papers anchoring the scientific record for this compound.
| Title | Year | Cited by | Topic |
|---|---|---|---|
| Drug-Induced Hepatotoxicity | 2003 | 1582 | Pharmacogenetics and Drug Metabolism |
| The Safety of Newly Approved Medicines | 1999 | 241 | Pharmaceutical Economics and Policy |
| European multicenter trial of the prevention of cystoid macular edema after cataract surgery in nondiabetics: ESCRS PREMED study report 1 | 2018 | 157 | Retinal Diseases and Treatments |
| Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium | 2006 | 111 | Synthesis and biological activity |
| A new approach to the analysis of analgesic drug trials, illustrated with bromfenac data | 1994 | 109 | Computational Drug Discovery Methods |
Frequently asked questions
Common questions about this compound's patent and research landscape, answered from the underlying data.
What is the molecular composition of Bromfenac sodium hydrate?
Which organizations hold the most patents for Bromfenac sodium hydrate?
What are the main research topics associated with Bromfenac sodium hydrate?
What does the patent literature reveal about formulation approaches for Bromfenac sodium hydrate?
What publication activity levels have been recorded for Bromfenac sodium hydrate research?