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Vantas

(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-3-(1-benzylimidazol-4-yl)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide · also: Vantaas, Supprelin, histrelin, Histrelina, Histreline, Histrelinum

FormulaC66H86N18O12
Mol. weight1323.528
PubChem CID25077993
InChIKeyHHXHVIJIIXKSOE-QILQGKCVSA-N
SMILESCCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC2=CN(C=N2)CC3=CC=CC=C3)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC5=CNC6=CC=CC=C65)NC(=O)[C@H](CC7=CN=CN7)NC(=O)[C@@H]8CCC(=O)N8
15,527Patents
93Research papers
2,108Patents - last 3 years
3Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Bayer Pharma AG1,246
2Merck Sharp and Dohme LLC631
3AbbVie Inc630
4Merck Patent GmbH616
5Bayer Intellectual Property GmbH476
6Bayer AG410
7Vertex Pharmaceuticals Inc342
8Human Genome Sciences Inc217
9Incyte Corp202
10Organon Pharma UK Ltd188

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)12,810
2A61KMedicinal preparations12,336
3C07DHeterocyclic compounds7,954
4C07KPeptides2,926
5C12NMicroorganisms, enzymes1,139
6G01NInvestigating / analysing materials992
7Y02AClimate change adaptation774
8C07CAcyclic and carbocyclic compounds686
9C07BGeneral methods of organic chemistry620
10C12QMeasuring/testing involving enzymes541

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
IMPLANTABLE DEVICE FOR THE DELIVERY OF HISTRELIN AND METHODS OF USE THEREOF2010Endo Pharmaceuticals Solutions Inc9
Histrelin synthesizing method2013BINHAI GL PEPTIDE CO., LTD.3
Method for synthesizing histrelin in full liquid phase2021Hunan Santai Pharmaceutical Co.,Ltd.1
Method for specifically synthesizing histrelin2017Guo Tai bio tech ltd, Hefei1
IMPLANTABLE DEVICE FOR THE DELIVERY OF HISTRELIN AND METHODS OF USE THEREOF2010Endo Pharmaceuticals Solutions Inc0

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Hormonal and reproductive studies1
2Prostate Cancer Diagnosis and Treatment1
3Sperm and Testicular Function1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Amicur FarkasShaare Zedek Medical Center8
2Boris ChertinShaare Zedek Medical Center8
3C. Wayne BardinPopulation Council7
4Erica A. EugsterIndiana University – Purdue University Indianapolis7
5Irving M. SpitzBen-Gurion University of the Negev7
6K. SundaramPopulation Council7
7David R. MeldrumUniversity of California, Los Angeles6
8John K.H. LuUniversity of California, Los Angeles6
9Marcelle I. CedarsUniversity of California, Los Angeles6
10Howard L. JuddUniversity of California, Los Angeles5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Vantas?

Vantas has the molecular formula C66H86N18O12 and a molecular weight of 1323.528 g/mol.

Which patent assignees hold the most patents related to this compound's technology space?

The leading patent assignees in this technology area are Bayer Pharma AG with 1246 patents, Merck Sharp and Dohme LLC with 631 patents, and AbbVie Inc with 630 patents.

What are the main therapeutic research areas associated with Vantas?

Key research topics include Treatment of endometriosis with a long-acting gonadotropin-releasing hormone agonist, Successful Treatment of Severe Premenstrual Syndrome by Combined Use of Gonadotropin-Releasing Hormone Agonist and Estrogen/Progestin, and The Role of Gonadotropin-Releasing Hormone in Murine Preimplantation Embryonic Development.

How many patents have been filed for histrelin delivery methods?

Notable patents include an Implantable Device for the Delivery of Histrelin and Methods of Use Thereof filed in 2010, as well as multiple synthesis method patents filed between 2013 and 2021 by various assignees.

What are the dominant patent classification codes for compounds in this space?

The most prevalent patent classification codes are A61P (pharmaceutical preparations) with 12,810 patents, A61K (preparations for medical purposes) with 12,336 patents, and C07D (heterocyclic compounds) with 7,954 patents.

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