Who owns the IP
The organizations most actively patenting around this compound, ranked by referenced patent volume.
| # | Assignee | Patents |
|---|---|---|
| 1 | Merck and Co Inc | 627 |
| 2 | Takeda Pharmaceutical Co Ltd | 404 |
| 3 | Sankyo Co Ltd | 148 |
| 4 | Eli Lilly and Co | 129 |
| 5 | Biora Therapeutics Inc | 70 |
| 6 | Takasago International Corp | 64 |
| 7 | Allergan Inc | 57 |
| 8 | Bristol Myers Co | 53 |
| 9 | Sumitomo Pharma Co Ltd | 49 |
| 10 | University of California, San Diego | 45 |
Explore the full landscape
This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.
Visit CyprisWhere innovation is concentrated
Patent classifications ranked by volume reveal the technical domains with the most active filing.
| # | Code | Area | Patents |
|---|---|---|---|
| 1 | A61P | Therapeutic activity (drug indications) | 2,299 |
| 2 | C07D | Heterocyclic compounds | 2,179 |
| 3 | A61K | Medicinal preparations | 2,000 |
| 4 | Y02P | Climate change mitigation: production | 728 |
| 5 | C07F | Organometallic compounds | 622 |
| 6 | C12N | Microorganisms, enzymes | 606 |
| 7 | C07C | Acyclic and carbocyclic compounds | 358 |
| 8 | C07K | Peptides | 345 |
| 9 | Y02A | Climate change adaptation | 308 |
| 10 | C12P | Fermentation, enzyme processes | 304 |
AI mapped opportunity space
This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.
See Cypris in actionMost-cited patents
Patents ranked by forward citations reveal the foundational inventions the field continues to build on.
| Title | Year | Assignee | Cited by |
|---|---|---|---|
| Substituted N-methylene derivatives of thienamycin | 1980 | Merck and Co Inc | 88 |
| Crystalline N-formimidoyl thienamycin | 1981 | Merck and Co Inc | 57 |
| Thienamycin renal peptidase inhibitors | 1992 | Merck and Co Inc | 39 |
| Process for the preparation of thienamycin and intermediates | 1980 | Merck and Co Inc | 33 |
| Synthesis of thienamycin via trans-3-carboxymethylene-4-carboxy-5-methyl-Δ2 -isoxazoline | 1981 | Merck and Co Inc | 31 |
Where research is gaining momentum
Research themes ranked by publication activity show where scientific interest is accelerating around this compound.
| # | Research topic | Papers |
|---|---|---|
| 1 | Historical Medical Research and Treatments | 1 |
| 2 | Infections and bacterial resistance | 1 |
| 3 | Metalloenzymes and iron-sulfur proteins | 1 |
Who's driving the science
The most-published authors working with this compound, alongside their primary affiliations.
| # | Author | Affiliation | Papers |
|---|---|---|---|
| 1 | Gloria Blanco | Universidad de Oviedo | 5 |
| 2 | Alfredo F. Braña | Universidad de Oviedo | 4 |
| 3 | Byron H. Arison | Merck & Co., Inc., Rahway, NJ, USA (United States) | 4 |
| 4 | Craig A. Townsend | Johns Hopkins University | 4 |
| 5 | Edward Inamine | Merck & Co., Inc., Rahway, NJ, USA (United States) | 4 |
| 6 | B. G. CHRISTENSEN | Merck & Co., Inc., Rahway, NJ, USA (United States) | 3 |
| 7 | Christopher J. Schofield | University of Oxford | 3 |
| 8 | Cármen Méndez | Universidad de Oviedo | 3 |
| 9 | Jerrold M. Liesch | Merck & Co., Inc., Rahway, NJ, USA (United States) | 3 |
| 10 | Joanne M. Williamson | Merck & Co., Inc., Rahway, NJ, USA (United States) | 3 |
Research leaders
This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.
See Cypris in actionThe literature that defines it
The most-cited papers anchoring the scientific record for this compound.
| Title | Year | Cited by | Topic |
|---|---|---|---|
| Metabolism of Thienamycin and Related Carbapenem Antibiotics by the Renal Dipeptidase, Dehydropeptidase-I | 1982 | 341 | Antibiotic Resistance in Bacteria |
| Carbapenems, a new class of beta-lactam antibiotics | 1985 | 290 | Antibiotic Resistance in Bacteria |
| Empirical antibacterial drug discovery—Foundation in natural products | 2006 | 243 | Microbial Natural Products and Biosynthesis |
| Secretion systems for secondary metabolites: how producer cells send out messages of intercellular communication | 2005 | 203 | Microbial Natural Products and Biosynthesis |
| Biosynthesis of fluorothreonine and fluoroacetic acid by the thienamycin producer, Streptomyces cattleya. | 1986 | 164 | Microbial Natural Products and Biosynthesis |
Frequently asked questions
Common questions about this compound's patent and research landscape, answered from the underlying data.
What is the molecular composition of Thienamycin?
Which organizations hold the most patents related to Thienamycin?
What are the primary technical classifications for Thienamycin patents?
What key research areas have been covered in Thienamycin literature?
What are the primary inventors and institutions advancing Thienamycin research?