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tetrahydromethanopterin

(2S)-2-[[(2R,3S,4R,5S)-5-[(2R,3S,4S)-5-[4-[[(1R)-1-[(6S,7S)-2-amino-7-methyl-4-oxo-5,6,7,8-tetrahydro-3H-pteridin-6-yl]ethyl]amino]phenyl]-2,3,4-trihydroxypentoxy]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxypentanedioic acid

FormulaC30H45N6O16P
Mol. weight776.6898
PubChem CID135398665
InChIKeySCBIBGUJSMHIAI-LHIIQLEZSA-N
SMILESC[C@H]1[C@@H](NC2=C(N1)N=C(NC2=O)N)[C@@H](C)NC3=CC=C(C=C3)C[C@@H]([C@@H]([C@@H](CO[C@@H]4[C@@H]([C@@H]([C@H](O4)COP(=O)(O)O[C@@H](CCC(=O)O)C(=O)O)O)O)O)O)O
143Patents
35Research papers
17Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Ascendis Pharma AS16
2Henkel AG and Co KGaA5
3Colorado State University Research Foundation4
4Harvard University4
5EIDP Inc3
6EnEvolv Inc3
7Merlion Pharmaceuticals GmbH3
8University of Minnesota System3
9Icos Corp2
10Washington University in St. Louis2

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C12NMicroorganisms, enzymes77
2A61KMedicinal preparations50
3C12PFermentation, enzyme processes47
4C07KPeptides42
5Y02EClimate change mitigation: energy42
6C12YEnzyme nomenclature (EC numbers)33
7Y02PClimate change mitigation: production18
8A61PTherapeutic activity (drug indications)17
9G01NInvestigating / analysing materials17
10C07CAcyclic and carbocyclic compounds14

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Genomics and Phylogenetic Studies1
2Metabolism and Genetic Disorders1
3Metal-Catalyzed Oxygenation Mechanisms1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Mary E. LidstromUniversity of Washington8
2Julia A. VorholtMax Planck Institute for Terrestrial Microbiology7
3Ludmila ChistoserdovaUniversity of Washington6
4Rudolf K. ThauerMax Planck Institute for Terrestrial Microbiology6
5Christopher J. MarxUniversity of Washington5
6R. S. WolfeUniversity of Illinois Urbana-Champaign4
7Marina KalyuzhnayaUniversity of Washington3
8Ulrich ErmlerMax Planck Institute of Biophysics3
9Christian GriesingerMax Planck Institute for Terrestrial Microbiology2
10Christoph H. HagemeierMax Planck Institute for Terrestrial Microbiology2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of tetrahydromethanopterin?

Tetrahydromethanopterin has the molecular formula C30H45N6O16P and a molecular weight of 776.6898 g/mol.

Which organization holds the most patents related to tetrahydromethanopterin?

Ascendis Pharma AS holds the most patents related to tetrahydromethanopterin, with 16 patents in the aggregate.

Who are the most prolific authors publishing on tetrahydromethanopterin?

The most prolific authors on tetrahydromethanopterin research are Mary E. Lidstrom from University of Washington with 8 papers, and Julia A. Vorholt from Max Planck Institute for Terrestrial Microbiology with 7 papers.

What are the primary patent classifications for tetrahydromethanopterin-related inventions?

The leading patent classifications are C12N (77 patents), A61K (50 patents), and C12P (47 patents), indicating focus on biotechnology, pharmaceutical preparations, and fermentation/bioproduction processes.

What is the trend in patent filings for tetrahydromethanopterin in recent years?

Patent filings show variability across 2016–2025, with peaks in 2024 (10 patents) and 2019 (7 patents). The last 3 years have seen 18 patents filed. No papers have been published on this compound in the last 3 years, though 35 papers were identified overall.

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