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Temoporfin

3-[10,15,20-tris(3-hydroxyphenyl)-2,3,23,24-tetrahydroporphyrin-5-yl]phenol

FormulaC44H32N4O4
Mol. weight680.764
PubChem CID136106195
InChIKeyKSXLETNRCMCRAQ-UHFFFAOYSA-N
SMILESC1CC2=NC1=C(C3=NC(=C(C4=CC=C(N4)C(=C5C=CC(=C2C6=CC(=CC=C6)O)N5)C7=CC(=CC=C7)O)C8=CC(=CC=C8)O)C=C3)C9=CC(=CC=C9)O
373Patents
468Research papers
157Patents - last 3 years
12Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1City of Hope20
2University of California, San Diego16
3University of California Berkeley13
4Mallinckrodt Inc10
5Verastem Inc10
6Harpoon Therapeutics Inc9
7Bayer AG8
8Mallinckrodt LLC8
9Merck Sharp & Dohme LLC8
10Genentech Inc6

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations305
2A61PTherapeutic activity (drug indications)270
3C07KPeptides101
4C07DHeterocyclic compounds85
5C12NMicroorganisms, enzymes48
6G01NInvestigating / analysing materials38
7C12QMeasuring/testing involving enzymes30
8A61N17
9Y02AClimate change adaptation16
10A61B15

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Photodynamic Therapy Research Studies11
2Advancements in Transdermal Drug Delivery2
3Chemical Synthesis and Analysis1
4Extracellular vesicles in disease1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1François GuilleminCentre de Recherche en Automatique de Nancy29
2Colin HopperUniversity College London26
3Alfred FahrFriedrich Schiller University Jena23
4Lina BezdetnayaCentre de Recherche en Automatique de Nancy21
5Georges WagnièresÉcole Polytechnique Fédérale de Lausanne19
6Hubert van den BerghÉcole Polytechnique Fédérale de Lausanne15
7Dietrich ScheglmannBiolitec (Germany)13
8Alexander J. MacRobertUniversity College London9
9Arno WieheSchott (Germany)9
10Heinrich WaltUniversity Hospital Zurich9

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical composition of Temoporfin?

Temoporfin has the molecular formula C44H32N4O4 with a molecular weight of 680.764. Its canonical chemical name is 3-[10,15,20-tris(3-hydroxyphenyl)-2,3,23,24-tetrahydroporphyrin-5-yl]phenol, and it is identified by the InChI Key KSXLETNRCMCRAQ-UHFFFAOYSA-N.

Which institutions lead in patent activity for Temoporfin?

The leading patent assignees for Temoporfin are City of Hope with 20 patents, University of California, San Diego with 16 patents, and University of California Berkeley with 13 patents. In the pharmaceutical sector, Mallinckrodt Inc and Verastem Inc each hold 10 patents.

What are the primary research topics associated with Temoporfin?

The dominant research topic is Photodynamic Therapy Research Studies, which accounts for 11 papers. Other research areas include Advancements in Transdermal Drug Delivery with 2 papers, Chemical Synthesis and Analysis with 1 paper, and Extracellular vesicles in disease with 1 paper.

Who are the most prolific authors publishing on Temoporfin?

François Guillemin has published 29 papers on Temoporfin, followed by Colin Hopper with 26 papers and Alfred Fahr with 23 papers. Other significant contributors include Lina Bezdetnaya with 21 papers and Georges Wagnières with 19 papers.

How has patent activity for Temoporfin changed in recent years?

Patent activity for Temoporfin showed significant growth recently, with 117 patents in 2022, 103 in 2023, and 84 in 2024. The last three years (2022–2024) account for 157 out of 373 total patents. Paper publication has remained more stable, with 12 papers published in the last three years.

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