Book a demo

Chemical intelligence powered by cypris.ai

TBE buffer

2-amino-2-(hydroxymethyl)propane-1,3-diol;2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid;boric acid · also: tris-borate EDTA, Tris-Borate-EDTA buffer, 5X, TBE (5X), TRIS + borate + EDTA, TBE (10X), TRIS + borate + EDTA, Tris Borate EDTA buffer, 10x, DNAse, RNAse and Protease free, pH 8.3, for molecular biology, 2-Amino-2-(hydroxymethyl)propane-1,3-diol 2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetraacetate borate

FormulaC14H30BN3O14
Mol. weight475.211
PubChem CID21257725
InChIKeyOSBLTNPMIGYQGY-UHFFFAOYSA-N
SMILESB(O)(O)O.C(CN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O.C(C(CO)(CO)N)O
16,921Patents
22Research papers
2,209Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Monsanto Technology LLC2,132
2Zymogenetics Inc273
3Novozymes Inc239
4Novozymes AS232
5Sirna Therapeutics Inc121
6Centre National de la Recherche Scientifique117
7Genentech Inc112
8The University of Texas System108
9Novartis AG103
10EIDP Inc91

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

Visit Cypris

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C12NMicroorganisms, enzymes7,133
2C12QMeasuring/testing involving enzymes4,616
3A61KMedicinal preparations4,506
4C07KPeptides4,444
5A61PTherapeutic activity (drug indications)4,167
6A01H2,284
7G01NInvestigating / analysing materials2,272
8C12PFermentation, enzyme processes1,247
9C12YEnzyme nomenclature (EC numbers)1,156
10Y02AClimate change adaptation1,087

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

See Cypris in action

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Microfluidic and Capillary Electrophoresis Applications1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Nancy C. StellwagenUniversity of Iowa3
2Attila ZsolnaiVeszprémi Érseki Hittudományi Fõiskola2
3Jun WangNational Institutes of Natural Sciences2
4László OrbánAgricultural Biotechnology Institute2
5Abraham WolcottLawrence Livermore National Laboratory1
6Adam SchwartzbergLawrence Livermore National Laboratory1
7Adrian R. Krainer1
8Akila MayedaCold Spring Harbor Laboratory1
9Alan D. FrankelUniversity of California, San Francisco1
10Alicia R. TiptonUniversity of California, San Francisco1

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

See Cypris in action

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical composition of TBE buffer?

TBE buffer is a mixture composed of three main components: tris (2-amino-2-(hydroxymethyl)propane-1,3-diol), boric acid, and EDTA (2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid). The combined molecular formula is C14H30BN3O14 with a molecular weight of 475.211 g/mol.

How much patent activity has been associated with TBE buffer?

TBE buffer has been mentioned in a total of 16,921 patents, with 2,209 patents filed in the last three years. This represents significant patent coverage across multiple fields of technology.

Which organizations hold the most patents mentioning TBE buffer?

The leading patent holders mentioning TBE buffer are Monsanto Technology LLC with 2,132 patents, followed by Zymogenetics Inc with 273 patents, Novozymes Inc with 239 patents, and Novozymes AS with 232 patents. Other significant assignees include Sirna Therapeutics Inc, Centre National de la Recherche Scientifique, Genentech Inc, The University of Texas System, Novartis AG, and EIDP Inc.

What technical fields use TBE buffer based on patent classification?

Patents mentioning TBE buffer are predominantly classified in biotechnology and life sciences fields. The largest classification is C12N (Microorganisms or Enzymes; Composition thereof) with 7,133 patents, followed by C12Q (Measuring or testing processes involving enzymes or microorganisms) with 4,616 patents, A61K (Preparations for medical purposes) with 4,506 patents, C07K (Organic compounds containing peptide bonds) with 4,444 patents, and A61P (Pharmaceutical preparations for specific therapeutic purposes) with 4,167 patents.

Who has published academic research on TBE buffer and its applications?

Nancy C. Stellwagen from the University of Iowa is the most prolific author associated with TBE buffer research, with 3 papers. Other notable authors include Attila Zsolnai and László Orbán, each with 2 papers. Research also involves scientists from institutions such as Lawrence Livermore National Laboratory, Cold Spring Harbor Laboratory, and the University of California, San Francisco.

Turn any compound into a complete chemical intelligence landscape

Go beyond static compound data. Cypris resolves identities, patents, papers, and commercial signals into one AI-powered view - so your team can move from a single chemical question to a complete R&D, IP, and market landscape.

Schedule a free trial