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Systral

2-[1-(4-chlorophenyl)-1-phenylethoxy]-N,N-dimethylethanamine;hydrochloride · also: Clorevan, Phenoxene, Chlorphenoxamine, Chlorphenoxamine HCl, Phenoxene hydrochloride, Contristamine Hydrochloride

FormulaC18H23Cl2NO
Mol. weight340.288
PubChem CID11223
InChIKeyPAQUKACYLLABHB-UHFFFAOYSA-N
SMILESCC(C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)OCCN(C)C.Cl
216Patents
26Research papers
7Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Yokohama Rubber Co Ltd52
2Esteve Pharmaceuticals SA18
3Wyeth Canada Inc14
4Kolon Industries Inc10
5Astellas Pharma Inc5
6Boehringer Ingelheim International GmbH5
7Goodyear Tire and Rubber Co5
8Rohto Pharmaceutical Co Ltd5
9Scripps Research Institute5
10Novartis AG4

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations98
2A61PTherapeutic activity (drug indications)71
3B60C65
4Y10TCross-reference (technical subjects)44
5B29D36
6C07DHeterocyclic compounds33
7C08LPolymer compositions (blends)22
8A61QCosmetics, personal care17
9B32BLayered products11
10A61N9

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Analytical Methods in Pharmaceuticals1
2Immunotoxicology and immune responses1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1E W PommerenkeHeidelberg University2
2H. OßwaldHeidelberg University2
3M VolmHeidelberg University2
4A Bazex1
5A Dupré1
6A. A. RenziAir University1
7Abreu Be1
8Ayman A. GoudaZagazig University1
9B Christol1
10Begley Rw1

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical composition and molecular formula of Systral?

Systral has the molecular formula C18H23Cl2NO and a molecular weight of 340.288. Its canonical chemical name is 2-[1-(4-chlorophenyl)-1-phenylethoxy]-N,N-dimethylethanamine;hydrochloride. The compound is also known by several synonyms including Clorevan, Phenoxene, and Chlorphenoxamine hydrochloride.

Which organizations hold the most patents related to Systral?

Yokohama Rubber Co Ltd holds the largest patent portfolio related to Systral with 52 patents. This is followed by Esteve Pharmaceuticals SA with 18 patents and Wyeth Canada Inc with 14 patents. Other significant patent holders include Kolon Industries Inc, Astellas Pharma Inc, Boehringer Ingelheim International GmbH, Goodyear Tire and Rubber Co, Rohto Pharmaceutical Co Ltd, Scripps Research Institute, and Novartis AG.

What are the main research topics covered in published literature on Systral?

Published research on Systral covers several key areas including analytical chemistry and chromatography methods for determining the compound in pharmaceutical preparations, neuroscience and neuropharmacology research focusing on anticonvulsant and antitremor effects, and synthesis with biological activity assessments. Additional studies address metabolism and analytical methods in pharmaceuticals.

What patent classifications are most frequently associated with Systral patents?

The most common patent classifications for Systral-related patents are A61K (pharmaceuticals) with 98 patents and A61P (therapeutic applications) with 71 patents. Other frequently appearing classifications include B60C (tire manufacturing) with 65 patents, Y10T (general classification) with 44 patents, B29D (plastic processing) with 36 patents, and C07D (organic chemistry) with 33 patents.

What is the current research activity level for Systral?

The total patent portfolio for Systral comprises 216 patents, with 7 patents filed in the last 3 years. Published research shows 26 papers on the compound overall, though there have been no new publications in the last 3 years. Patent activity peaked in 2017 with 14 filings and has remained modest in recent years.

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