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Sulfolithocholyltaurine

2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-sulfooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid · also: Taurolithocholate sulfate, Taurolithocholate sulphate, Taurosulfolithocholic acid, taurolithocholic acid sulfate, Taurolithocholic acid sulphate

FormulaC26H45NO8S2
Mol. weight563.765
PubChem CID440071
InChIKeyHSNPMXROZIQAQD-GBURMNQMSA-N
SMILESC[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)OS(=O)(=O)O)C)C
323Patents
56Research papers
23Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Boehringer Ingelheim International GmbH121
2Calcimedica Inc12
3Vertex Pharmaceuticals Inc10
4Boehringer Ingelheim Pharma GmbH and Co KG8
5Childrens Hospital of Philadelphia CHOP7
6Boehringer Ingelheim Pharmaceuticals Inc6
7University of California San Diego UCSD6
8Millennium Pharmaceuticals Inc5
9Labcorp Holdings Inc4
10University of California4

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)243
2C07DHeterocyclic compounds213
3A61KMedicinal preparations151
4G01NInvestigating / analysing materials60
5Y02AClimate change adaptation43
6G16B17
7C07KPeptides16
8C12QMeasuring/testing involving enzymes13
9C07J10
10G16C10

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Drug Transport and Resistance Mechanisms2

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Alexei V. TepikinUniversity of Liverpool10
2Robert SuttonUniversity of Liverpool7
3David N. CriddleUniversity of Liverpool6
4Dieter HäussingerHeinrich Heine University Düsseldorf6
5Ole H. PetersenUniversity of Liverpool6
6Oleg V. GerasimenkoUniversity of Liverpool5
7Roland ReinehrHeinrich Heine University Düsseldorf5
8Sohail Z. HusainUniversity of Pittsburgh5
9Svetlana VoroninaUniversity of Liverpool5
10Abrahim I. OrabiUniversity of Pittsburgh Medical Center4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Sulfolithocholyltaurine?

Sulfolithocholyltaurine has a molecular formula of C26H45NO8S2 and a molecular weight of 563.765 g/mol.

Which organizations hold the most patents related to Sulfolithocholyltaurine?

Boehringer Ingelheim International GmbH holds the largest patent portfolio with 121 patents, followed by Calcimedica Inc with 12 patents and Vertex Pharmaceuticals Inc with 10 patents.

What are the primary research topics associated with Sulfolithocholyltaurine?

Research on Sulfolithocholyltaurine focuses on pancreatitis pathology and treatment, protein kinase regulation and GTPase signaling, liver disease diagnosis and treatment, and cell death mechanisms and regulation. A notable study examined how taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase–dependent manner.

Who are the leading researchers publishing on Sulfolithocholyltaurine?

Alexei V. Tepikin from the University of Liverpool has published 10 papers on this compound, followed by Robert Sutton and David N. Criddle, also from the University of Liverpool, with 7 and 6 papers respectively.

What patent classification areas dominate the Sulfolithocholyltaurine patent landscape?

The largest proportion of patents are classified under A61P (pharmaceutical preparations) with 243 patents, followed by C07D (heterocyclic compounds) with 213 patents, and A61K (preparations for medical purposes) with 151 patents.

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