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Dexetimide

(3S)-3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione · also: Serenone, Tremblex, Dexetimida, Dexetimidum, Dexbenzelimid, Dexbenzetimid

FormulaC23H26N2O2
Mol. weight362.473
PubChem CID30843
InChIKeyLQQIVYSCPWCSSD-HSZRJFAPSA-N
SMILESC1CN(CCC1[C@@]2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=CC=C4
810Patents
121Research papers
42Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Koninklijke Philips NV55
2Janssen Pharmaceutica NV48
3Egalet Ltd35
4Noven Pharmaceuticals Inc35
5Amicus Therapeutics Inc31
6Aquestive Therapeutics Inc24
7The University of Texas System20
8Chienna BV19
9Entero Therapeutics Inc19
10GridAI Technologies Corp19

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations691
2A61PTherapeutic activity (drug indications)493
3C07DHeterocyclic compounds135
4A61LSterilising / disinfecting materials63
5G01NInvestigating / analysing materials60
6C08LPolymer compositions (blends)59
7Y02AClimate change adaptation48
8Y10TCross-reference (technical subjects)46
9A61MDevices for introducing media into the body41
10C12NMicroorganisms, enzymes38

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Receptor Mechanisms and Signaling3
2Chemical Reactions and Mechanisms1
3Cholinesterase and Neurodegenerative Diseases1
4Neurobiology and Insect Physiology Research1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Dick de ZeeuwUniversity of Groningen9
2Pierre M. LaduronJanssen (Belgium)9
3Henry N. WagnerJohns Hopkins University7
4Alan A. WilsonJohns Hopkins University7
5Michael KassiouAustralian Nuclear Science and Technology Organisation7
6Robert F. DannalsJohns Hopkins University7
7Harbans LalUniversity of Rhode Island6
8A. WauquierJanssen (Belgium)5
9Andrew KatsifisAustralian Nuclear Science and Technology Organisation5
10C. J. E. NiemegeersJanssen (Belgium)5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Dexetimide?

Dexetimide has the molecular formula C23H26N2O2 and a molecular weight of 362.473 g/mol.

Which organizations have the most patents related to Dexetimide?

Koninklijke Philips NV has the highest number of patents with 55, followed by Janssen Pharmaceutica NV with 48 patents, and Egalet Ltd and Noven Pharmaceuticals Inc each with 35 patents.

What are the primary research topics associated with Dexetimide in the scientific literature?

The main research topics include Receptor Mechanisms and Signaling, Chemical Reactions and Mechanisms, Cholinesterase and Neurodegenerative Diseases, and Neurobiology and Insect Physiology Research.

What key research has been published on Dexetimide's interaction with muscarinic receptors?

Notable research includes a 1979 study on stereospecific in vitro binding of [³H]dexetimide to brain muscarinic receptors, and a 1988 study on the synthesis of radiotracers including [11C]dexetimide for studying muscarinic cholinergic receptors in the living human brain using positron emission tomography.

How has patent activity for Dexetimide changed in recent years?

Patent filings have generally declined from peak years, with 41 patents filed in 2016 and 2020, declining to 12 patents in 2025 and 2 patents projected for 2026. In the last 3 years, there have been 42 patents filed total.

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