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Serenone

(3S)-3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione · also: Tremblex, Levetimide, Dexetimida, Dexetimidum, Benzetimide, Dexbenzelimid

FormulaC23H26N2O2
Mol. weight362.473
PubChem CID30843
InChIKeyLQQIVYSCPWCSSD-HSZRJFAPSA-N
SMILESC1CN(CCC1[C@@]2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=CC=C4
810Patents
121Research papers
42Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Koninklijke Philips NV55
2Janssen Pharmaceutica NV48
3Egalet Ltd35
4Noven Pharmaceuticals Inc35
5Amicus Therapeutics Inc31
6Aquestive Therapeutics Inc24
7The University of Texas System20
8Chienna BV19
9Entero Therapeutics Inc19
10American Regent Inc11

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations691
2A61PTherapeutic activity (drug indications)493
3C07DHeterocyclic compounds135
4A61LSterilising / disinfecting materials63
5G01NInvestigating / analysing materials60
6C08LPolymer compositions (blends)59
7Y02AClimate change adaptation48
8Y10TCross-reference (technical subjects)46
9A61MDevices for introducing media into the body41
10C12NMicroorganisms, enzymes38

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Receptor Mechanisms and Signaling3
2Chemical Reactions and Mechanisms1
3Cholinesterase and Neurodegenerative Diseases1
4Neurobiology and Insect Physiology Research1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Dick de ZeeuwUniversity of Groningen9
2Pierre M. LaduronJanssen (Belgium)9
3Henry N. WagnerJohns Hopkins University7
4Alan A. WilsonJohns Hopkins University7
5Michael KassiouAustralian Nuclear Science and Technology Organisation7
6Robert F. DannalsJohns Hopkins University7
7Harbans LalUniversity of Rhode Island6
8A. WauquierJanssen (Belgium)5
9Andrew KatsifisAustralian Nuclear Science and Technology Organisation5
10C. J. E. NiemegeersJanssen (Belgium)5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical structure of Serenone?

Serenone has the IUPAC name (3S)-3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione with molecular formula C23H26N2O2 and molecular weight 362.473. Its InChI Key is LQQIVYSCPWCSSD-HSZRJFAPSA-N.

What alternative names is Serenone known by?

Serenone is sold under multiple trade names and synonyms, including Tremblex, Levetimide, Dexetimida, Dexetimidum, Benzetimide, Dexbenzelimid, Dexbenzetimid, Dexbenzetimide, Dextrobenzetimide, and dextro-Benzetimide.

Which organizations hold the most patents related to Serenone?

The leading patent assignees for Serenone are Koninklijke Philips NV (55 patents), Janssen Pharmaceutica NV (48 patents), Egalet Ltd (35 patents), and Noven Pharmaceuticals Inc (35 patents).

What research topics are associated with published Serenone studies?

Published research on Serenone spans several topics including Receptor Mechanisms and Signaling, Chemical Reactions and Mechanisms, Cholinesterase and Neurodegenerative Diseases, and Neurobiology and Insect Physiology Research. Notable papers focus on muscarinic receptors and positron emission tomography imaging applications.

What is the recent patent activity trend for Serenone?

Patent activity for Serenone peaked in 2017 with 47 patents filed. In the last three years, filing activity has declined, with 25 patents in 2022, 24 in 2023, and 17 in 2024, totaling 44 patents filed in the last three years overall.

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