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Dexetimide

(3S)-3-(1-benzylpiperidin-4-yl)-3-phenylpiperidine-2,6-dione · also: Serenone · Tremblex · Dexetimida · Dexetimidum · Dexbenzelimid · Dexbenzetimid

FormulaC23H26N2O2
Mol. weight362.473
PubChem CID30843
InChIKeyLQQIVYSCPWCSSD-HSZRJFAPSA-N
SMILESC1CN(CCC1[C@@]2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=CC=C4
810Patents
121Research papers122 indexed in detail
40Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Koninklijke Philips NV55
2Johnson and Johnson48
3Hisamitsu Pharmaceutical Co Inc44
4Assertio Holdings Inc40
5Biomarin Pharmaceutical Inc31
6Dr Reddys Laboratories Ltd27
7Aquestive Therapeutics Inc24
8The University of Texas System20
9GridAI Technologies Corp19
10H Lundbeck AS15

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations691
2A61PTherapeutic activity (drug indications)493
3C07DHeterocyclic compounds135
4A61LSterilising / disinfecting materials63
5G01NInvestigating / analysing materials60
6C08LPolymer compositions (blends)59
7Y02AClimate change adaptation48
8Y10TCross-reference (technical subjects)46
9A61MDevices for introducing media into the body41
10C12NMicroorganisms, enzymes38

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Solubility parameter based drug delivery system and method for altering drug saturation concentration1997Hisamitsu Pharmaceutical Co Inc686
Compositions and methods for topical administration of pharmaceutically active agents1998Hisamitsu Pharmaceutical Co Inc639
Bioadhesive compositions and methods for topical administration of active agents2003Hisamitsu Pharmaceutical Co Inc505
METHODS AND COMPOSITIONS OF BIOLOGICALLY ACTIVE AGENTS2017Wave Life Sciences Pte Ltd149
Compositions and methods for topical administration of pharmaceutically active agents1995Hisamitsu Pharmaceutical Co Inc500

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20171
20211

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Dick de ZeeuwUniversity of Groningen9
2Pierre M. LaduronJanssen (Belgium)9
3Robert F. DannalsJohns Hopkins University7
4Michael KassiouAustralian Nuclear Science and Technology Organisation7
5Alan A. WilsonJohns Hopkins University7
6Henry N. WagnerJohns Hopkins University6
7A. WauquierJanssen (Belgium)5
8Christian Loc’hCommissariat à l'Énergie Atomique et aux Énergies Alternatives5
9Hayden T. RavertJohns Hopkins University5
10K. EnsingUniversity of Groningen5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Dexetimide?

Dexetimide has the molecular formula C23H26N2O2 and a molecular weight of 362.473 g/mol.

Which companies hold the most patents related to Dexetimide?

The leading patent assignees for Dexetimide are Koninklijke Philips NV with 55 patents, Johnson and Johnson with 48 patents, and Hisamitsu Pharmaceutical Co Inc with 44 patents.

What are the most highly-cited patents involving Dexetimide?

The most highly-cited patents are US-5656286-A (686 citations) and US-5719197-A (639 citations), both assigned to Hisamitsu Pharmaceutical Co Inc and relating to drug delivery systems and topical administration methods.

What research topics are most represented in the scientific literature on Dexetimide?

Research on Dexetimide primarily focuses on neuroscience and neuropharmacology, particularly studies of muscarinic receptor binding and function. Notable papers include work on stereospecific binding of Dexetimide to brain muscarinic receptors and synthesis of radiotracers using Dexetimide for positron emission tomography imaging.

What are the dominant patent classification codes for Dexetimide-related inventions?

The most frequent patent classifications are A61K (pharmaceuticals; medicinal preparations) with 691 patents, A61P (pharmaceutical or medicinal preparations for specific therapeutic purposes) with 493 patents, and C07D (heterocyclic compounds) with 135 patents.

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