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Selank

(2S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxylic acid · also: Selanc · TP-7 (diacetate) · Thr-Lys-Pro-Arg-Pro-Gly-Pro · Threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline · L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-Proline

FormulaC33H57N11O9
Mol. weight751.887
PubChem CID11765600
InChIKeyJTDTXGMXNXBGBZ-YVHUGQOKSA-N
SMILESC[C@H]([C@@H](C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N2CCC[C@H]2C(=O)NCC(=O)N3CCC[C@H]3C(=O)O)N)O
358Patents
70Research papers
91Patents - last 3 years
1Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Massachusetts Institute of Technology38
2Ascendis Pharma AS29
3Harvard University28
4State University System of Florida14
5Imperial Brands PLC13
6Virginia Polytechnic Institute and State University10
7Regeneron Pharmaceuticals Inc9
8Toray Industries Inc6
9Biomarin Pharmaceutical Inc3
10Dow Inc3

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations244
2A61PTherapeutic activity (drug indications)153
3C07KPeptides140
4C12NMicroorganisms, enzymes112
5Y02AClimate change adaptation30
6C12YEnzyme nomenclature (EC numbers)29
7C08JWorking-up of plastics18
8A61MDevices for introducing media into the body16
9C12QMeasuring/testing involving enzymes15
10A24F14

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
USE OF PEPTIDE Thr-Lys-Pro-Arg-Pro-Gly-Pro (SELANC) HEPATOPROTECTIVE FOR EXPOSURE IN ACUTE IMMOBILISATION STRESS20164
APPLICATION OF Thr-Lys-Pro-Arg-Pro-Gly-Pro PEPTIDE (SELANK) FOR TOXIC HEPATITIS PREVENTION AND TREATMENT20173
USE OF THE PEPTIDE Thr-Lys-Pro-Arg-Pro-Gly-Pro (SELANK) TO INCREASE BODY RESISTANCE TO ACUTE HYPOTHERMIA20190

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20163
20176
20194
20203
20211
20221
20251

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1N. F. MyasoedovInstitute of Molecular Genetics19
2Л. А. АндрееваInstitute of Molecular Genetics18
3Н. В. КостMental Health Research Center of Russian Academy of Medical Sciences12
4O. Yu. SokolovMental Health Research Center of Russian Academy of Medical Sciences12
5И. И. КозловскийInstitute of Pharmacology Russian Academy of Medical Sciences10
6М. И. ШадринаInstitute of Molecular Genetics8
7Timur KolominInstitute of Molecular Genetics8
8Yu. A. ZolotarevInstitute of Molecular Genetics7
9P. A. SlominskyInstitute of Molecular Genetics6
10Kozlovskaia Mm6

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Selank?

Selank has the molecular formula C33H57N11O9 and a molecular weight of 751.887. Its canonical IUPAC name is (2S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxylic acid. It is also known by the peptide sequence notation Thr-Lys-Pro-Arg-Pro-Gly-Pro.

Which institutions hold the most patents related to Selank?

Massachusetts Institute of Technology leads with 38 patents, followed by Ascendis Pharma AS with 29 patents and Harvard University with 28 patents.

What research trends are evident in Selank-related publications and patents?

Patent activity has increased significantly in recent years, with 50 patents filed in 2023 and 44 in 2024, compared to 14 in 2016. Paper publication has been sporadic, with only 70 total papers identified and just 1 paper published in 2025, though 19 papers were published in 2016.

What are the primary research areas associated with Selank according to patent classifications?

Selank research spans multiple therapeutic and chemical domains. The dominant classification is A61K (medicinal preparations), appearing in 244 patents, followed by A61P (pharmaceutical specific therapeutic activity), appearing in 153 patents. Chemical synthesis and peptide-related work is represented by C07K (peptides) in 140 patents and C12N (microorganism or enzyme related techniques) in 112 patents.

Who are the leading authors in Selank research?

N. F. Myasoedov from the Institute of Molecular Genetics is the most prolific author with 19 papers, followed closely by Л. А. Андреева, also from the Institute of Molecular Genetics, with 18 papers. Both Н. В. Кост and O. Yu. Sokolov have each contributed 12 papers, with Sokolov affiliated with the Mental Health Research Center of Russian Academy of Medical Sciences.

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