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Salsoline

(1R)-7-methoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol · also: D-salosine, D-Salsoline, methylsalsolinol

FormulaC11H15NO2
Mol. weight193.246
PubChem CID40010
InChIKeyYTPRLBGPGZHUPD-SSDOTTSWSA-N
SMILESC[C@@H]1C2=CC(=C(C=C2CCN1)O)OC
58Patents
56Research papers
7Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Wanhua Chemical Group Co Ltd2
2Consortium fuer Elektrochemische Industrie GmbH1
3Sony Group Corp1
4University of California San Diego UCSD1
5University of Florida1

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations16
2A61PTherapeutic activity (drug indications)12
3C07DHeterocyclic compounds10
4G01NInvestigating / analysing materials7
5Y02PClimate change mitigation: production7
6Y02AClimate change adaptation6
7C07CAcyclic and carbocyclic compounds5
8B01JChemical/physical processes (e.g. catalysts)4
9C07BGeneral methods of organic chemistry4
10C07FOrganometallic compounds4

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Process for extracting salsoline from Common Russianthistle Herb2012Nanjing Zelang Medical Technology Co., Ltd.0
Method extracting salsoline A from salsola collina2012Nanjing Zelang Medical Technology Co., Ltd.0
Preparation method of salsoline2011Nanjing Zelang Medical Technology Co., Ltd.0

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Cell death mechanisms and regulation1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Makoto NaoiInstitute of Applied Biochemistry30
2Wakako MaruyamaNational Center for Geriatrics and Gerontology20
3W. MaruyamaNational Center for Geriatrics and Gerontology11
4P. DostertStructure Fédérative de Recherche en Biologie et Santé de Rennes10
5Tsutomu TakahashiAichi Konan College8
6Hong YiNational Institute of Biotechnology7
7Yukihiro AkaoNational Institute of Biotechnology7
8Yulin DengNagoya Institute of Technology7
9Masao KawaiNagoya Institute of Technology3
10Moussa B. H. YoudimTechnion – Israel Institute of Technology3

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of salsoline?

Salsoline has the molecular formula C11H15NO2 and a molecular weight of 193.246 g/mol. Its canonical IUPAC name is (1R)-7-methoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-6-ol.

What are the main research topics associated with salsoline in the scientific literature?

The literature on salsoline is heavily focused on neuroscience and neuropharmacology, with particular emphasis on dopaminergic neurotoxicity and its relevance to Parkinson's disease. Key research topics include cell death of dopamine neurons in aging and Parkinson's disease, dopamine-derived endogenous compounds, and neurotransmitter receptor influence on behavior.

Which patent assignees hold intellectual property related to salsoline?

Patent assignees with salsoline-related IP include Wanhua Chemical Group Co Ltd (2 patents), Consortium fuer Elektrochemische Industrie GmbH (1 patent), Sony Group Corp (1 patent), University of California San Diego UCSD (1 patent), and University of Florida (1 patent). Additionally, Nanjing Zelang Medical Technology Co., Ltd. holds patents on salsoline extraction and preparation methods.

What analytical methods have been developed for salsoline detection?

An assay method has been developed for the (R)- and (S)-enantiomers of salsolinols in biological samples and foods using ion-pair high-performance liquid chromatography with β-cyclodextrin as a chiral mobile phase additive. This analytical approach is classified under the Analytical Chemistry and Chromatography research topic.

What are the primary patent classification areas for salsoline-related inventions?

The majority of salsoline patents fall under CPC subclass A61K (16 patents), covering pharmaceutical preparations. Other significant classifications include A61P (12 patents, pharmaceutical preparations for specific therapeutic purposes), C07D (10 patents, heterocyclic compounds), and G01N (7 patents, investigating or analyzing materials). These classifications reflect both pharmaceutical applications and chemical synthesis methods.

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