Who owns the IP
The organizations most actively patenting around this compound, ranked by referenced patent volume.
| # | Assignee | Patents |
|---|---|---|
| 1 | Shanghai Institute of Materia Medica of CAS | 9 |
| 2 | Institute of Materia Medica, CAMS&PUMC | 3 |
| 3 | Xel Pharmaceuticals Inc | 3 |
| 4 | Zhejiang University | 3 |
| 5 | Institute of Chinese Materia Medica of China Academy of Chinese Medical Sciences | 2 |
| 6 | Zhejiang Chinese Medicine University ZCMU | 2 |
| 7 | Guangdong Yifang Pharmaceutical Co Ltd | 1 |
| 8 | Jiyang College of Zhejiang A&F University | 1 |
| 9 | Shimadzu China Co Ltd | 1 |
| 10 | Xinjiang Technical Institute of Physics & Chemistry | 1 |
Explore the full landscape
This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.
Visit CyprisWhere innovation is concentrated
Patent classifications ranked by volume reveal the technical domains with the most active filing.
| # | Code | Area | Patents |
|---|---|---|---|
| 1 | A61K | Medicinal preparations | 68 |
| 2 | A61P | Therapeutic activity (drug indications) | 54 |
| 3 | C07D | Heterocyclic compounds | 32 |
| 4 | G01N | Investigating / analysing materials | 10 |
| 5 | Y02A | Climate change adaptation | 6 |
| 6 | A61Q | Cosmetics, personal care | 4 |
| 7 | A23L | Foods and beverages (general) | 3 |
| 8 | A23V | Foods, foodstuffs - indexing scheme | 3 |
| 9 | C07B | General methods of organic chemistry | 3 |
| 10 | C07C | Acyclic and carbocyclic compounds | 3 |
AI mapped opportunity space
This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.
See Cypris in actionMost-cited patents
Patents ranked by forward citations reveal the foundational inventions the field continues to build on.
| Title | Year | Assignee | Cited by |
|---|---|---|---|
| Method for synthesizing rotundine with berberine as raw material | 2017 | China Pharmaceutical (Leshan) Co., Ltd. | 5 |
| Corydalis B long-acting preparation and its preparing method | 2005 | MENG FANHAO | 5 |
| Application of the tetrahydropalmatine in anti-toxicity of cisplatin medicine is prepared | 2017 | Zhejiang University | 4 |
| Levo-tetrahydropalmatine transdermal drug delivery preparation | 2011 | ZHEJIANG ACADEMY OF MEDICAL SCIENCES | 4 |
| Application of tetrahydropalmatine enantiomers in preparation of P-glycoprotein inhibitor | 2011 | Zhejiang University | 4 |
Where research is gaining momentum
Research themes ranked by publication activity show where scientific interest is accelerating around this compound.
| # | Research topic | Papers |
|---|---|---|
| 1 | Berberine and alkaloids research | 1 |
| 2 | Chemical synthesis and alkaloids | 1 |
| 3 | Neuroscience and Neuropharmacology Research | 1 |
| 4 | Pharmacogenetics and Drug Metabolism | 1 |
Who's driving the science
The most-published authors working with this compound, alongside their primary affiliations.
| # | Author | Affiliation | Papers |
|---|---|---|---|
| 1 | Guo-Zhang Jin | Shanghai Institute of Materia Medica | 14 |
| 2 | Guorong Fan | Second Military Medical University | 11 |
| 3 | Huidi Jiang | Zhejiang University | 7 |
| 4 | Yifeng Chai | Second Military Medical University | 7 |
| 5 | Zhanying Hong | Second Military Medical University | 6 |
| 6 | Fan Yang | Capital Medical University | 5 |
| 7 | Hanfa Zou | Dalian Institute of Chemical Physics | 5 |
| 8 | Hongliang Su | Shanxi Medical University | 5 |
| 9 | Jia Bei Wang | University of Maryland, Baltimore | 5 |
| 10 | Bin Hsu | Shanghai Institute of Materia Medica | 4 |
Research leaders
This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.
See Cypris in actionThe literature that defines it
The most-cited papers anchoring the scientific record for this compound.
| Title | Year | Cited by | Topic |
|---|---|---|---|
| Protective effect of tetrahydropalmatine against d-galactose induced memory impairment in rat | 2015 | 119 | Antioxidants, Aging, Portulaca oleracea |
| Determination of dl-tetrahydropalmatine in Corydalis yanhusuo by l-tetrahydropalmatine imprinted monolithic column coupling with reversed-phase high performance liquid chromatography | 2006 | 118 | Analytical chemistry methods development |
| The Clinical Spectrum of Jin Bu Huan Toxicity | 1996 | 108 | Complementary and Alternative Medicine Studies |
| L -Tetrahydropalamatine: A Potential New Medication for the Treatment of Cocaine Addiction | 2012 | 102 | Neurotransmitter Receptor Influence on Behavior |
| Levo-tetrahydropalmatine attenuates cocaine self-administration and cocaine-induced reinstatement in rats | 2007 | 96 | Neurotransmitter Receptor Influence on Behavior |
Frequently asked questions
Common questions about this compound's patent and research landscape, answered from the underlying data.
What is the molecular composition and structure of Rotundine?
Which institutions hold the most patents related to Rotundine?
What are the primary research topics associated with Rotundine publications?
What are the main patent classification categories for Rotundine inventions?
How has research output on Rotundine trended in recent years?