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Robison ester

[(2R,3S,4S,5R)-3,4,5,6-tetrahydroxyoxan-2-yl]methyl dihydrogen phosphate

FormulaC6H13O9P
Mol. weight260.1348
PubChem CID5958
InChIKeyNBSCHQHZLSJFNQ-GASJEMHNSA-N
SMILESC([C@@H]1[C@H]([C@@H]([C@H](C(O1)O)O)O)O)OP(=O)(O)O
28,367Patents
3,260Research papers
2,059Patents - last 3 years
40Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Ionis Pharmaceuticals Inc563
2F Hoffmann La Roche AG342
3Abbott Laboratories328
4Novartis AG287
5Bayer Pharma AG257
6Auspex Pharmaceuticals Inc240
7Evonik Operations GmbH225
8Janssen Pharmaceutica NV218
9Bayer Intellectual Property GmbH208
10University of California San Diego UCSD164

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)13,240
2A61KMedicinal preparations10,946
3C12NMicroorganisms, enzymes8,910
4C07DHeterocyclic compounds7,852
5C07KPeptides4,749
6G01NInvestigating / analysing materials4,640
7C12PFermentation, enzyme processes4,405
8C12YEnzyme nomenclature (EC numbers)3,117
9C12QMeasuring/testing involving enzymes2,787
10C07CAcyclic and carbocyclic compounds1,536

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
A kind of Robison ester ((R)-(-) -3- hydroxy-2-methyl methyl propionate) and its derivative and its synthetic method2019Shanghai Maosheng Kaihui Technology Co., Ltd.0

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Pancreatic function and diabetes12
2Glycogen Storage Diseases and Myoclonus5
3Carbohydrate Chemistry and Synthesis4
4Erythrocyte Function and Pathophysiology4
5Mitochondrial Function and Pathology4
6Advanced Glycation End Products research3
7Enzyme Structure and Function3
8Fungal and yeast genetics research3
9Metabolism and Genetic Disorders3
10Metabolism, Diabetes, and Cancer3

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Joan J. GuinovartUniversitat de Barcelona19
2Rivka BeitnerBar-Ilan University18
3Abdullah SenerUniversité Libre de Bruxelles17
4Angelo BenedettiUniversity of Siena14
5Ann N. BurchellNinewells Hospital13
6Janice Y. ChouNational Institutes of Health11
7Abram KatzKarolinska Institutet11
8Josep CarrerasUniversitat de Barcelona10
9Gerald I. ShulmanYale University9
10A.R. Ferré-D′AmaréNational Heart Lung and Blood Institute8

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Robison ester?

Robison ester has the molecular formula C6H13O9P and a molecular weight of 260.1348. Its canonical chemical name is [(2R,3S,4S,5R)-3,4,5,6-tetrahydroxyoxan-2-yl]methyl dihydrogen phosphate.

Which organizations hold the most patents related to Robison ester?

The leading patent holders are Ionis Pharmaceuticals Inc with 563 patents, F Hoffmann La Roche AG with 342 patents, and Abbott Laboratories with 328 patents. Other significant holders include Novartis AG, Bayer Pharma AG, and Auspex Pharmaceuticals Inc.

What research topics are most frequently associated with Robison ester in the academic literature?

The most prominent research topic is Pancreatic function and diabetes with 11 papers. Other significant topics include Glycogen Storage Diseases and Myoclonus, Erythrocyte Function and Pathophysiology, Mitochondrial Function and Pathology, and Advanced Glycation End Products research.

Which academic researchers have published the most papers on Robison ester?

Joan J. Guinovart from Universitat de Barcelona leads with 19 papers, followed by Rivka Beitner from Bar-Ilan University with 18 papers and Abdullah Sener from Université Libre de Bruxelles with 17 papers. Other prolific authors include Angelo Benedetti and Ann N. Burchell.

How has patent and publication activity for Robison ester changed in recent years?

Patent activity shows an overall upward trend, with 2023 recording 1,128 patents and 2024 recording 1,016 patents. Recent years (2022–2024) show sustained high patent counts. Academic publication activity has been lower and more variable, with 19 papers in 2024 and 11 papers in 2025.

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