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Quinagolide

(3S,4aS,10aR)-3-(diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline · also: Norprolac · Quinagolida · Quinagolidum · (3S,4aS,10aR)-3-((diethylsulfamoyl)amino)-1-propyl-1H,2H,3H,4H,4aH,5H,10H,10aH-benzo(g)quinolin-6-ol

FormulaC20H33N3O3S
Mol. weight395.562
PubChem CID3086401
InChIKeyGDFGTRDCCWFXTG-ZIFCJYIRSA-N
SMILESCCCN1C[C@H](C[C@H]2[C@H]1CC3=C(C2)C(=CC=C3)O)NS(=O)(=O)N(CC)CC
1,935Patents
194Research papers192 indexed in detail
201Patents - last 3 years
3Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Bayer AG1,003
2German Cancer Research Center130
3Dana Farber Cancer Institute Inc65
4Ferring Holding SA63
5Case Western Reserve University36
6Harvard University33
7Mass General Brigham Inc23
8Ceva Sante Animale SA21
9Aquestive Therapeutics Inc19
10Technion Israel Institute of Technology19

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations1,693
2A61PTherapeutic activity (drug indications)1,684
3C07DHeterocyclic compounds1,016
4C07KPeptides126
5C07CAcyclic and carbocyclic compounds86
6C07FOrganometallic compounds76
7Y02AClimate change adaptation73
8G01NInvestigating / analysing materials72
9C07BGeneral methods of organic chemistry66
10C12QMeasuring/testing involving enzymes64

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
DRUG-DEVICE UNIT CONTAINING QUINAGOLIDE2016Ferring Holding SA4
DRUG-DEVICE UNIT CONTAINING QUINAGOLIDE20172
STEREOSELECTIVE SYNTHESIS OF INTERMEDIATES AND SYNTHESIS OF QUINAGOLIDS2024Ferring Holding SA0
Pharmaceutical device unit containing quinagolide2023Ferring Holding SA0
Drug-device unit containing quinagolide2016Ferring Holding SA0

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20164
20173
20182
20191
20211
20222
20231
20241
20251

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Judith BrownellRadboud University Nijmegen19
2P. LacasseAgriculture and Agri-Food Canada10
3Annamaria ColaoUniversity of Naples Federico II10
4P JaquetHôpital de la Timone9
5Diego FeroneFederico II University Hospital9
6Francesca SarnacchiaroFederico II University Hospital8
7Gaetano LombardiUniversity of Naples Federico II8
8S. OllierAgriculture and Agri-Food Canada7
9Carolina Di SommaFederico II University Hospital7
10Antonella Di SarnoFederico II University Hospital7

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition and structure of Quinagolide?

Quinagolide has the molecular formula C20H33N3O3S with a molecular weight of 395.562. Its canonical name is (3S,4aS,10aR)-3-(diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline, and it is also known by the trade name Norprolac. The compound's InChI key is GDFGTRDCCWFXTG-ZIFCJYIRSA-N.

Which organizations hold the most patents related to Quinagolide?

Bayer AG leads with 1003 patents related to Quinagolide, followed by the German Cancer Research Center with 130 patents and Dana Farber Cancer Institute Inc with 65 patents. Ferring Holding SA holds 63 patents and is a significant assignee in recent patent filings on the compound.

What is the trend in patent and publication activity for Quinagolide over recent years?

Patent activity related to Quinagolide showed a peak around 2016–2017 (161–180 patents per year) and has gradually declined, with 92 patents in 2024 and only 12 in 2026. Academic publication activity is sparse, with only 3 papers published in the last 3 years (2022–2024). Total coverage includes 1935 patents and 194 papers in the aggregate.

What are the main research topics associated with Quinagolide in the scientific literature?

The published research on Quinagolide spans multiple topics including pituitary gland disorders and treatments, neurotransmitter receptor influence on behavior, and growth hormone and insulin-like growth factors. Key papers include studies on dopamine D1 and D2 receptor localization, prolactinomas in children and adolescents, and the effect of dopaminergic agents in the treatment of acromegaly.

What are the leading patent classification codes for intellectual property covering Quinagolide?

The most common patent classifications are A61K (1693 patents) and A61P (1684 patents), both relating to pharmaceutical preparations and therapeutic applications. Organic chemical synthesis is represented by C07D (1016 patents). Other significant classifications include C07K (126 patents), C07C (86 patents), and C07F (76 patents), reflecting the compound's chemical synthesis and formulation focus.

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