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Pyoverdin

4-[[1-[[(2R)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2R)-1-[[(2S)-5-[formyl(hydroxy)amino]-1-[[(3S,6S,9S,12S)-9-[3-[formyl(hydroxy)amino]propyl]-3,6-bis[(1R)-1-hydroxyethyl]-2,5,8,11-tetraoxo-1,4,7,10-tetrazacyclohexadec-12-yl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamoyl]-8,9-dihydroxy-2,3,4,4a-tetrahydro-1H-pyrimido[1,2-a]quinolin-5-yl]amino]-4-oxobutanoic acid · also: Pyoverdine, Pyoverdin D, Pyoverdin Pf, Pyoverdine PvdI, Ferric pyoverdin

FormulaC55H85N17O22
Mol. weight1336.382
PubChem CID5289234
InChIKeyIXTLVPXCZJJUQB-VYJQSIGYSA-N
SMILESC[C@H]([C@H]1C(=O)N[C@H](C(=O)NCCCC[C@@H](C(=O)N[C@H](C(=O)N1)CCCN(C=O)O)NC(=O)[C@H](CCCN(C=O)O)NC(=O)[C@@H](CO)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](CO)NC(=O)C2CCNC3N2C4=CC(=C(C=C4C=C3NC(=O)CCC(=O)O)O)O)[C@@H](C)O)O
567Patents
537Research papers
159Patents - last 3 years
27Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
13M Innovative Properties Co68
2Haptogen Ltd18
3Grünenthal GmbH13
4The University of Texas System10
5Columbia University9
6Astellas Pharma Inc8
7Council of Scientific and Industrial Research7
8Henkel AG and Co KGaA7
9Solventum Intellectual Properties Co7
10University of California, San Diego7

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations276
2A61PTherapeutic activity (drug indications)236
3C12NMicroorganisms, enzymes162
4Y02AClimate change adaptation130
5C07KPeptides111
6G01NInvestigating / analysing materials108
7A01NPreservation of bodies; biocides; pest repellents102
8C12QMeasuring/testing involving enzymes73
9C12R56
10C07DHeterocyclic compounds53

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Proteins specific for pyoverdine and pyochelin2018Pieris Pharmaceuticals GmbH1
A novel protein specific for pyoverdine and pyokerin2021ピエリス ファーマシューティカルズ ゲーエムベーハー0
Fusion molecules with binding specificity for pyoverdin type I, II and III and pyoquelin2018SANOFI0
Novel proteins specific for pyoverdine and pyochelin2017Pieris Pharmaceuticals GmbH0
Specific proteins for pyoverdin and pyoquelin2017SANOFI0

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Bacterial Genetics and Biotechnology2
2Microbial Fuel Cells and Bioremediation2
3Photosynthetic Processes and Mechanisms2
4Plant-Microbe Interactions and Immunity2
5Porphyrin Metabolism and Disorders2
6Antibiotic Resistance in Bacteria1
7Cassava research and cyanide1
8Legume Nitrogen Fixing Symbiosis1
9Nosocomial Infections in ICU1
10Plant Pathogenic Bacteria Studies1

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1H. BudzikiewiczUniversity of Cologne37
2Isabelle J. SchalkCentre National de la Recherche Scientifique31
3Jean‐Marie MeyerCentre National de la Recherche Scientifique31
4Iain L. LamontUniversity of Otago24
5Pierre CornélisVrije Universiteit Brussel22
6Christine BaysseVrije Universiteit Brussel12
7F. PattusCentre National de la Recherche Scientifique11
8Ashleigh S. GriffinUniversity of Oxford9
9K. TarazUniversity of Cologne9
10Paolo ViscaRoma Tre University9

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Pyoverdin?

Pyoverdin has the molecular formula C55H85N17O22 with a molecular weight of 1336.382 g/mol. Its InChI Key is IXTLVPXCZJJUQB-VYJQSIGYSA-N. The compound is also known by several synonyms including Pyoverdine, Pyoverdin D, Pyoverdin Pf, and Pyoverdine PvdI.

What are the leading patent assignees in the Pyoverdin field?

The top patent assignees related to Pyoverdin are 3M Innovative Properties Co with 68 patents, Haptogen Ltd with 18 patents, and Grünenthal GmbH with 13 patents. Other significant assignees include The University of Texas System (10 patents), Columbia University (9 patents), and Astellas Pharma Inc (8 patents).

Who are the most prolific researchers publishing on Pyoverdin?

Leading authors in Pyoverdin research include H. Budzikiewicz from University of Cologne with 37 papers, Isabelle J. Schalk and Jean‐Marie Meyer, both from Centre National de la Recherche Scientifique, each with 31 papers, and Iain L. Lamont from University of Otago with 24 papers.

What are the main patent classification areas for Pyoverdin-related inventions?

The primary patent classifications for Pyoverdin are A61K (276 patents) covering pharmaceutical preparations, A61P (236 patents) for therapeutic uses, and C12N (162 patents) for biotechnology. Other significant classifications include Y02A (130 patents) for environmental technologies and C07K (111 patents) for peptide chemistry.

What are the most-cited papers on Pyoverdin and its biological role?

Highly-cited papers include 'Iron and Pseudomonas aeruginosa biofilm formation' (794 citations), 'Siderophore-mediated signaling regulates virulence factor production in Pseudomonas aeruginosa' (579 citations), and 'Pyoverdin is essential for virulence of Pseudomonas aeruginosa' (525 citations). These papers fall within the Bacterial Genetics and Biotechnology research topic.

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