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Pyoverdin

4-[[1-[[(2R)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2R)-1-[[(2S)-5-[formyl(hydroxy)amino]-1-[[(3S,6S,9S,12S)-9-[3-[formyl(hydroxy)amino]propyl]-3,6-bis[(1R)-1-hydroxyethyl]-2,5,8,11-tetraoxo-1,4,7,10-tetrazacyclohexadec-12-yl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]carbamoyl]-8,9-dihydroxy-2,3,4,4a-tetrahydro-1H-pyrimido[1,2-a]quinolin-5-yl]amino]-4-oxobutanoic acid · also: Pyoverdine · Pyoverdin D · Pyoverdin Pf · Pyoverdine PvdI · Ferric pyoverdin

FormulaC55H85N17O22
Mol. weight1336.382
PubChem CID5289234
InChIKeyIXTLVPXCZJJUQB-VYJQSIGYSA-N
SMILESC[C@H]([C@H]1C(=O)N[C@H](C(=O)NCCCC[C@@H](C(=O)N[C@H](C(=O)N1)CCCN(C=O)O)NC(=O)[C@H](CCCN(C=O)O)NC(=O)[C@@H](CO)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](CO)NC(=O)C2CCNC3N2C4=CC(=C(C=C4C=C3NC(=O)CCC(=O)O)O)O)[C@@H](C)O)O
567Patents
537Research papers
150Patents - last 3 years
27Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
13M Co68
2Pfizer Inc18
3Grünenthal Pharma GmbH and Co KG13
4Siemens AG10
5The University of Texas System10
6Columbia University9
7Astellas Pharma Inc8
8Council of Scientific and Industrial Research7
9Henkel AG and Co KGaA7
10Solventum Corp7

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations276
2A61PTherapeutic activity (drug indications)236
3C12NMicroorganisms, enzymes162
4Y02AClimate change adaptation130
5C07KPeptides111
6G01NInvestigating / analysing materials108
7A01NPreservation of bodies; biocides; pest repellents102
8C12QMeasuring/testing involving enzymes73
9C12R56
10C07DHeterocyclic compounds53

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Proteins specific for pyoverdine and pyochelin2018Palvella Therapeutics Inc1
A novel protein specific for pyoverdine and pyokerin20210
Fusion molecules with binding specificity for pyoverdin type I, II and III and pyoquelin20180
Novel proteins specific for pyoverdine and pyochelin2017Palvella Therapeutics Inc0
Specific proteins for pyoverdin and pyoquelin20170

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
201619
201724
201825
201917
202018
20217
20228
20237
202416
20254

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1H. BudzikiewiczUniversity of Cologne40
2Pierre CornélisVrije Universiteit Brussel28
3Iain L. LamontUniversity of Otago27
4Isabelle J. SchalkCentre National de la Recherche Scientifique27
5Jean‐Marie MeyerCentre National de la Recherche Scientifique18
6Mohamed Abou‐Elwafa AbdallahCentre National de la Recherche Scientifique13
7F. PattusCentre National de la Recherche Scientifique12
8Francesco ImperiSapienza University of Rome11
9Paolo ViscaRoma Tre University10
10Ashleigh S. GriffinUniversity of Oxford9

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Pyoverdin?

Pyoverdin has the molecular formula C55H85N17O22 with a molecular weight of 1336.382. Its InChI Key is IXTLVPXCZJJUQB-VYJQSIGYSA-N.

Which organizations have filed the most patents related to Pyoverdin?

3M Co leads with 68 patents, followed by Pfizer Inc with 18 patents and Grünenthal Pharma GmbH and Co KG with 13 patents. The University of Texas System and Columbia University have also contributed significantly with 10 and 9 patents respectively.

What are the primary research areas for Pyoverdin patents and publications?

Patent classification shows focus on A61K (pharmaceutical preparations), A61P (therapeutic uses), and C12N (microorganism technologies), collectively accounting for 674 patents. Published papers primarily address Bacterial Genetics and Biotechnology topics, including Pyoverdin's role in bacterial virulence and biofilm formation.

Who are the most prolific authors publishing on Pyoverdin?

H. Budzikiewicz from University of Cologne leads with 40 papers, followed by Pierre Cornélis from Vrije Universiteit Brussel with 28 papers. Iain L. Lamont from University of Otago and Isabelle J. Schalk from Centre National de la Recherche Scientifique have each published 27 papers on the compound.

How has research activity on Pyoverdin changed in recent years?

Patent activity has increased substantially, with 66 patents filed in 2022, 85 in 2023, and 71 in 2024, representing a peak in the last three years with 150 total patents. Paper publications show more modest recent activity with 16 papers in 2024 and 4 in 2025 from the tracked corpus.

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