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Procyanidin B3

(2R,3S)-2-(3,4-dihydroxyphenyl)-8-[(2R,3S,4S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol · also: C-(4a,8)-C · Procyanidin B-3 · Proanthocyanidin B3 · proanthocyanidin B-3 · catechin 4-8 catechin · Procyanidin Impurity 8

FormulaC30H26O12
Mol. weight578.526
PubChem CID146798
InChIKeyXFZJEEAOWLFHDH-AVFWISQGSA-N
SMILESC1[C@@H]([C@H](OC2=C1C(=CC(=C2[C@H]3[C@@H]([C@H](OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC(=C(C=C6)O)O)O
366Patents
49Research papers
52Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Suntory Holdings Ltd35
2Barry Callebaut AG10
3Chinese Academy of Sciences9
4Kikkoman Corp9
5Nutricos Technologies SNC8
6Anheuser Busch InBev SA6
7Henkel AG and Co KGaA4
8JNC Corp4
9Salzgitter AG4
10Givaudan SA3

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations144
2A61PTherapeutic activity (drug indications)119
3A23LFoods and beverages (general)87
4A61QCosmetics, personal care63
5A23VFoods, foodstuffs - indexing scheme61
6C07DHeterocyclic compounds32
7C12C30
8A23FCoffee, tea; their substitutes23
9G01NInvestigating / analysing materials23
10A23C21

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
The extracting method of Proanthocyanidins from Grape Seeds high polymer cracking and Proanthocyanidin B320191
Composition for improving flexibility of blood vessels, composition for improving vascular endothelial function, composition for inhibiting platelet aggregation, composition for improving blood flow, and transoral composition being characterized by containing (A) catechin and (B) proanthocyanidin B320230

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20164
20173
20181
20194
20206
20211

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Nuno MateusUniversidade do Porto7
2Víctor de FreitasUniversidade do Porto6
3Mirei MizunoSHOWA Medical University3
4Rosa Pérez-GregórioUniversidade do Porto3
5Kiyoshi FukuharaShowa Pharmaceutical University3
6Takashi YoshidaOkayama University2
7Seong Jun SeoChung-Ang University2
8Tsutomu HatanoOkayama University2
9Seong Soo JooGangneung–Wonju National University2
10Natércia F. BrásUniversidade do Porto2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Procyanidin B3?

Procyanidin B3 has the molecular formula C30H26O12 with a molecular weight of 578.526. Its canonical structure is (2R,3S)-2-(3,4-dihydroxyphenyl)-8-[(2R,3S,4S)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol.

Which organizations hold the most patents involving Procyanidin B3?

Suntory Holdings Ltd leads with 35 patents, followed by Barry Callebaut AG with 10 patents and Chinese Academy of Sciences with 9 patents. Kikkoman Corp and Nutricos Technologies SNC each hold 9 and 8 patents respectively.

What are the main research areas covered by patents for Procyanidin B3?

Patent coverage is concentrated in pharmaceutical and food applications. The leading CPC subclasses are A61K (pharmaceutical preparations, 144 patents), A61P (therapeutic applications, 119 patents), and A23L (food composition, 87 patents). Additional significant areas include A61Q (cosmetics, 63 patents) and A23V (vegetable preparations, 61 patents).

What research topics have been explored in published papers about Procyanidin B3?

Published research covers multiple areas including interactions with proteins in food systems, analytical determination of procyanidins in beverages via high-performance liquid chromatography, structural features of copigmentation with polyphenols, mechanisms of tannin-induced enzyme inhibition, and potential therapeutic applications in prostate cancer treatment through histone acetyltransferase inhibition.

Which researchers are most active in publishing studies on Procyanidin B3?

Nuno Mateus of Universidade do Porto has published 7 papers on the topic, followed by Víctor de Freitas, also of Universidade do Porto, with 6 papers. Other prolific authors include Mirei Mizuno of SHOWA Medical University, Rosa Pérez-Gregório of Universidade do Porto, and Kiyoshi Fukuhara of Showa Pharmaceutical University, each with 3 papers.

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