Who owns the IP
The organizations most actively patenting around this compound, ranked by referenced patent volume.
| # | Assignee | Patents |
|---|---|---|
| 1 | Symrise AG | 344 |
| 2 | Human Genome Sciences Inc | 252 |
| 3 | Coca Cola Co | 236 |
| 4 | Bayer Pharma AG | 159 |
| 5 | Novartis AG | 134 |
| 6 | Pharmacia and Upjohn Co | 88 |
| 7 | Merck and Co Inc | 76 |
| 8 | Cormatrix Cardiovascular Inc | 72 |
| 9 | Hoffmann La Roche Inc | 69 |
| 10 | F Hoffmann La Roche AG | 67 |
Explore the full landscape
This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.
Visit CyprisWhere innovation is concentrated
Patent classifications ranked by volume reveal the technical domains with the most active filing.
| # | Code | Area | Patents |
|---|---|---|---|
| 1 | A61K | Medicinal preparations | 3,054 |
| 2 | A61P | Therapeutic activity (drug indications) | 2,877 |
| 3 | C07J | 2,460 | |
| 4 | C12N | Microorganisms, enzymes | 741 |
| 5 | C07K | Peptides | 638 |
| 6 | C07D | Heterocyclic compounds | 565 |
| 7 | A61Q | Cosmetics, personal care | 529 |
| 8 | G01N | Investigating / analysing materials | 418 |
| 9 | A23L | Foods and beverages (general) | 415 |
| 10 | C07C | Acyclic and carbocyclic compounds | 320 |
AI mapped opportunity space
This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.
See Cypris in actionMost-cited patents
Patents ranked by forward citations reveal the foundational inventions the field continues to build on.
| Title | Year | Assignee | Cited by |
|---|---|---|---|
| 3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | 2013 | Sage Therapeutics Inc | 172 |
| Neuroactive steroids of the androstane and pregnane series | 1999 | Purdue Pharma LP | 170 |
| Method, compositions, and compounds for allosteric modulation of the gaba receptor by members of the androstane and pregnane series | 1999 | Cocensys Inc | 162 |
| Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series | 1993 | University of Southern California | 160 |
| Methods for allosteric modulation of the GABA receptor by members of the androstane and pregnane series | 2001 | Cocensys Inc | 108 |
Where research is gaining momentum
Research themes ranked by publication activity show where scientific interest is accelerating around this compound.
| # | Research topic | Papers |
|---|---|---|
| 1 | Pharmacogenetics and Drug Metabolism | 22 |
| 2 | Drug Transport and Resistance Mechanisms | 6 |
| 3 | Computational Drug Discovery Methods | 2 |
| 4 | Vitamin D Research Studies | 2 |
| 5 | Vitamin K Research Studies | 2 |
| 6 | Criminal Justice and Corrections Analysis | 1 |
| 7 | Ectopic Pregnancy Diagnosis and Management | 1 |
| 8 | Esophageal Cancer Research and Treatment | 1 |
| 9 | Estrogen and related hormone effects | 1 |
| 10 | Fibroblast Growth Factor Research | 1 |
Technology trend analysis
Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.
See Cypris in actionWho's driving the science
The most-published authors working with this compound, alongside their primary affiliations.
| # | Author | Affiliation | Papers |
|---|---|---|---|
| 1 | Curtis D. Klaassen | University of Kansas Medical Center | 23 |
| 2 | Jean‐Marc Pascussi | Inserm | 22 |
| 3 | Masahiko Negishi | National Institutes of Health | 22 |
| 4 | Wen Xie | University of Pittsburgh | 21 |
| 5 | Frank J. Gonzalez | National Institutes of Health | 15 |
| 6 | Matthew R. Redinbo | University of North Carolina at Chapel Hill | 14 |
| 7 | Sean Ekins | University of Maryland, Baltimore | 13 |
| 8 | Patrick Maurel | Inserm | 12 |
| 9 | Erin G. Schuetz | St. Jude Children's Research Hospital | 11 |
| 10 | Steven A. Kliewer | Research Triangle Park Foundation | 11 |
Research leaders
This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.
See Cypris in actionThe literature that defines it
The most-cited papers anchoring the scientific record for this compound.
| Title | Year | Cited by | Topic |
|---|---|---|---|
| Nuclear Receptors and Lipid Physiology: Opening the X-Files | 2001 | 2076 | Peroxisome Proliferator-Activated Receptors |
| Induction of phase I, II and III drug metabolism/transport by xenobiotics | 2005 | 1262 | Pharmacogenetics and Drug Metabolism |
| Vitamin D Receptor As an Intestinal Bile Acid Sensor | 2002 | 1163 | Vitamin D Research Studies |
| Neurosteroids: endogenous regulators of the GABAA receptor | 2005 | 1148 | Neuroscience and Neuropharmacology Research |
| Hormone Therapy and Venous Thromboembolism Among Postmenopausal Women | 2007 | 844 | Venous Thromboembolism Diagnosis and Management |
Frequently asked questions
Common questions about this compound's patent and research landscape, answered from the underlying data.
What is the molecular composition of Pregnane?
Which companies hold the most patents related to Pregnane?
What are the primary research areas in published literature on Pregnane?
What are the most highly-cited academic papers on Pregnane-related research?
What is the distribution of Pregnane-related patents by CPC classification?