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phthalate

phthalate · also: z phthalate, phthalic acid, o-phthalic acid, o-dicarboxybenzene, Disodium phthalate, Phthalic Acid Ester

FormulaC8H4O4-2
PubChem CID181977
InChIKeyXNGIFLGASWRNHJ-UHFFFAOYSA-L
SMILESC1=CC=C(C(=C1)C(=O)[O-])C(=O)[O-]
18,070Patents
3,884Research papers
942Patents - last 3 years
894Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1China Petroleum and Chemical Corp222
2BASF SE183
3EIDP Inc141
4Sinopec Beijing Research Institute of Chemical Industry95
5Eastman Kodak Co81
6Perrigo Pharma International DAC81
7Evonik Operations GmbH63
8ExxonMobil Chemical Patents Inc60
9General Electric Co60
10Borealis GmbH52

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations3,817
2C08LPolymer compositions (blends)3,464
3C08KPolymer compositions (additives)3,075
4A61PTherapeutic activity (drug indications)2,563
5C08GPolymers from non-vinyl bonds (e.g. polyamides, polyesters)1,381
6C08JWorking-up of plastics1,244
7C08FPolymers from C=C unsaturated bonds1,233
8C09DCoatings, paints, varnishes1,191
9Y10TCross-reference (technical subjects)1,027
10C07CAcyclic and carbocyclic compounds837

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Phenolic resin-polyisocyanate binder systems containing dialkyl phthalate solvents1975Ashland LLC55
A REPLACEMENT PLASTICIZER SYSTEM FOR PHTHALATE-PLASTICIZED FORMULATIONS2009Union Carbide Chemicals and Plastics Technology LLC51
Adhesive compositions from phthalate polymers and the preparation thereof1998SEYDEL COMPANIES, INC.49
Phthalate free nail polish enamel composition1999Tevco Enterprises Inc45
Self-compatibilizing phthalate-based polyester polyols1987Stepan Co39

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Effects and risks of endocrine disrupting chemicals49
2Environmental and Analytical Chemistry Studies2
33D Printing in Biomedical Research1
4Advanced Photocatalysis Techniques1
5Anesthesia and Sedative Agents1
6Aquatic Ecosystems and Phytoplankton Dynamics1
7Biochemical and biochemical processes1
8Biopolymer Synthesis and Applications1
9Dialysis and Renal Disease Management1
10Electrolyte and hormonal disorders1

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Antonia M. CalafatCenters for Disease Control and Prevention116
2John D. MeekerUniversity of Michigan49
3Russ HauserHarvard University48
4Kurunthachalam KannanNew York State Department of Health44
5Jodi A. FlawsUniversity of Illinois Urbana-Champaign34
6Leonardo TrasandeNew York University28
7Joseph M. BraunBrown University25
8Kelly K. FergusonNational Institute of Environmental Health Sciences24
9Sheela SathyanarayanaUniversity of Washington22
10Paige L. WilliamsHarvard University20

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

TitleYearCited byTopic
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals20152349Toxic Organic Pollutants Impact
Phthalates: Toxicology and exposure20071478Effects and risks of endocrine disrupting chemicals
What Are the Sources of Exposure to Eight Frequently Used Phthalic Acid Esters in Europeans?20061012Effects and risks of endocrine disrupting chemicals
Plastics and Health Risks2010860Effects and risks of endocrine disrupting chemicals
Phthalates and other additives in plastics: human exposure and associated health outcomes2009819Toxic Organic Pollutants Impact

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical composition of phthalate?

Phthalate has the molecular formula C8H4O4-2 and is also known by several synonyms including o-benzenedicarboxylic acid and phthalic acid. It is a divalent anion compound with InChI Key XNGIFLGAXYSFRNHJ-UHFFFAOYSA-L.

Which organizations hold the most patents related to phthalate?

The leading patent assignees for phthalate-related inventions are China Petroleum and Chemical Corp with 222 patents, BASF SE with 183 patents, and EIDP Inc with 141 patents. Other major assignees include Sinopec Beijing Research Institute of Chemical Industry, Eastman Kodak Co, and Perrigo Pharma International DAC.

What are the primary research topics associated with phthalate publications?

The dominant research topic for phthalate-related papers is Effects and risks of endocrine disrupting chemicals, which covers 37 papers. This reflects significant scholarly focus on phthalates as endocrine-disrupting substances, as evidenced by highly-cited works such as EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals and Phthalates: Toxicology and exposure.

Who are the most prolific researchers studying phthalates?

Leading researchers on phthalate topics include Antonia M. Calafat from the Centers for Disease Control and Prevention with 114 papers, John D. Meeker from the University of Michigan with 49 papers, and Russ Hauser from Harvard University with 48 papers. Other prominent contributors include Kurunthachalam Kannan from the New York State Department of Health and Jodi A. Flaws from the University of Illinois Urbana-Champaign.

What is the patent landscape for phthalate applications by CPC classification?

Phthalate patents span multiple CPC subclasses, with the highest concentration in A61K (pharmaceutical preparations, 3817 patents) and C08L (compositions of macromolecular compounds, 3464 patents). Other significant classifications include C08K (fillers and reinforcing materials, 3075 patents), A61P (specific therapeutic activity of chemical compounds, 2563 patents), and C08G (macromolecular compounds from non-condensation reactions, 1381 patents).

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