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(25R)-5alpha-Spirostan-3beta-ol

5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16-ol · also: 3-Episarsasapogenin · (25S)-Spirostan-3beta-ol · (25r)-5a-spirostan-3b-ol · (25R)-5.alpha.-Spirostan-3.beta.-ol

FormulaC27H44O3
Mol. weight416.646
PubChem CID219836
InChIKeyGMBQZIIUCVWOCD-UHFFFAOYSA-N
SMILESCC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)OC1
1,061Patents
30Research papers
64Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Berkshire Hathaway Inc55
2L'Oréal SA37
3Symrise AG32
4Pfizer Inc31
5Thermo Fisher Scientific Inc27
6AbbVie Inc25
7Toshiba Corp24
8Procter and Gamble Co23
9Fiore Holding SRL22
10Chinese Academy of Sciences21

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations565
2A61PTherapeutic activity (drug indications)368
3A61QCosmetics, personal care224
4C07J159
5C08LPolymer compositions (blends)69
6A61LSterilising / disinfecting materials59
7G01NInvestigating / analysing materials48
8A01NPreservation of bodies; biocides; pest repellents41
9C08B41
10C08GPolymers from non-vinyl bonds (e.g. polyamides, polyesters)37

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Cleansing articles for skin and/or hair which also deposit skin care actives2002Procter and Gamble Co355
Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses2013Yarrow Bioscience Inc175
Cleansing and conditioning article for skin or hair2000Procter and Gamble Co350
Esters of hyaluronic acid1989Fiore Holding SRL396
AH RECEPTOR ANTAGONISTS2007Symrise AG160

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20221

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Bertrand LiagreUniversité de Limoges5
2Cécile CorbièreUniversité de Limoges4
3Jean‐Louis BeneytoutUniversité de Limoges3
4Guoping CaiUniversity Town of Shenzhen2
5Yukihiro ShoyamaNagasaki International University2
6Pascale Vergne‐SalleHôpital Dupuytren2
7Scott W. NelsonIowa State University2
8Hua ZhouUniversity Town of Shenzhen2
9Naili WangShenyang Pharmaceutical University2
10Yaou ZhangUniversity Town of Shenzhen2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of (25R)-5alpha-Spirostan-3beta-ol?

(25R)-5alpha-Spirostan-3beta-ol has a molecular formula of C27H44O3 with a molecular weight of 416.646. Its InChI key is GMBQZIIUCVWOCD-UHFFFAOYSA-N.

Which companies hold the most patents involving this compound?

Berkshire Hathaway Inc leads with 55 patents, followed by L'Oréal SA with 37 patents, and Symrise AG with 32 patents. Other major patent holders include Pfizer Inc (31 patents), Thermo Fisher Scientific Inc (27 patents), and AbbVie Inc (25 patents).

What is the patent landscape trend for this compound in recent years?

Patent filings peaked in 2017 with 54 patents and have shown a general declining trend through 2024 (21 patents). The most recent year with data (2026) shows only 4 patents. The last three years of available data (2022–2024) contain a total of 98 patents.

Which research institutions have published the most on this compound?

Bertrand Liagre from Université de Limoges has authored the most papers (5), followed by Cécile Corbière also from Université de Limoges (4 papers). Jean‐Louis Beneytout from Université de Limoges contributed 3 papers. Overall, 30 papers were identified in the scientific literature.

What are the primary patent classification areas for this compound?

The compound is predominantly classified under pharmaceutical and cosmetic patent categories. Class A61K (pharmaceuticals and cosmetics) dominates with 565 patents, followed by A61P (specific therapeutic activities, 368 patents) and A61Q (cosmetics, 224 patents). Natural product chemistry class C07J accounts for 159 patents.

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