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Parigenin

5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16-ol · also: Tigogenin, Sarsaponin, Smilagenin, Sarsasapogenin, Episarsasapogenin, epi-Sarsasapogenin

FormulaC27H44O3
Mol. weight416.646
PubChem CID219836
InChIKeyGMBQZIIUCVWOCD-UHFFFAOYSA-N
SMILESCC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)OC1
1,061Patents
30Research papers
71Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Lipotec SA39
2L'Oréal SA37
3Symrise AG32
4Pfizer Inc31
5Pfizer Corp SRL29
6Patheon Softgels Inc27
7Procter and Gamble Co23
8Fidia Farmaceutici SpA22
9DIC Corp21
10Fidia SpA21

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations565
2A61PTherapeutic activity (drug indications)368
3A61QCosmetics, personal care224
4C07J159
5C08LPolymer compositions (blends)69
6A61LSterilising / disinfecting materials59
7G01NInvestigating / analysing materials48
8A01NPreservation of bodies; biocides; pest repellents41
9C08B41
10A23LFoods and beverages (general)36

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis1986Medical Research Foundation of Oregon77
Smilagenin and its use2001PHYTOPHARM PLC38
COMPOSITION COMPRISING SARSASAPOGENIN2008Sederma SA22
Tigogenin-cellobioside and its heptaacetate, methods for their preparation, and pharmaceutical compositions containing tigogenin-cellobioside1985Medical Research Foundation of Oregon16
Process for the preparation of tigogenin beta-cellobioside1990Pfizer Corp Belgium13

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Phytochemical Studies and Bioactivities2
2Bee Products Chemical Analysis1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Bertrand LiagreUniversité de Limoges5
2Cécile CorbièreUniversité de Limoges4
3Jean‐Louis BeneytoutUniversité de Limoges3
4Guoping CaiUniversity Town of Shenzhen2
5Hiroyuki TanakaKyushu University2
6Hua ZhouUniversity Town of Shenzhen2
7Naili WangShenyang Pharmaceutical University2
8Pascale Vergne‐SalleHôpital Dupuytren2
9Scott W. NelsonIowa State University2
10Xi YangAir Force Medical University2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical composition and molecular structure of Parigenin?

Parigenin has the molecular formula C27H44O3 with a molecular weight of 416.646. Its canonical IUPAC name is 5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16-ol, and it is also known by several synonyms including Tigogenin, Sarsaponin, Smilagenin, and Sarsasapogenin.

Which companies hold the most patents related to Parigenin?

Lipotec SA leads with 39 patents, followed by LOreal SA with 37 patents and Symrise AG with 32 patents. Other significant patent holders include Pfizer Inc with 31 patents, Pfizer Corp SRL with 29 patents, and Patheon Softgels Inc with 27 patents.

What are the primary patent application areas for Parigenin-related inventions?

The largest number of patents fall under CPC subclass A61K (medicinal preparations), with 565 patents. The next major areas are A61P (therapeutic applications), with 368 patents, and A61Q (cosmetic preparations), with 224 patents. Additional significant coverage includes C07J (steroid chemistry) with 159 patents and C08L (macromolecular compounds) with 69 patents.

Who are the leading researchers publishing on Parigenin?

Bertrand Liagre from Université de Limoges is the most prolific author with 5 papers. Cécile Corbière from Université de Limoges has published 4 papers, and Jean‐Louis Beneytout, also from Université de Limoges, has 3 papers. Other notable researchers include Guoping Cai and Hua Zhou, both from University Town of Shenzhen, and Hiroyuki Tanaka from Kyushu University, each with 2 papers.

What patents have had the greatest impact on the field based on citation counts?

The patent with the highest citations is a 1986 U.S. patent on Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis with 77 citations. The 2001 U.S. patent on Smilagenin and its use received 38 citations, and a 2008 World Patent on a composition comprising Sarsasapogenin received 22 citations.

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