Book a demo

Chemical intelligence powered by cypris.ai

p-Nitrophenyl sulfate

(4-nitrophenyl) hydrogen sulfate · also: p-Nitrophenol sulfate · 4-Nitrophenyl sulfate · p-nitrophenyl sulphate · P-Nitrophenol sulphate · para-Nitrophenyl sulfate · para-nitrophenyl sulphate

FormulaC6H5NO6S
Mol. weight219.167
PubChem CID80349
InChIKeyJBGHTSSFSSUKLR-UHFFFAOYSA-N
SMILESC1=CC(=CC=C1[N+](=O)[O-])OS(=O)(=O)O
318Patents
83Research papers
30Patents - last 3 years
1Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Steris PLC26
23M Co18
3DSM Firmenich AG12
4Massachusetts Institute of Technology12
5Merck KGaA9
6Sanofi SA8
7University of California8
8Novartis AG7
9Otsuka Holdings Co Ltd7
10Bristol Myers Squibb Co6

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

Visit Cypris

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1C12NMicroorganisms, enzymes174
2C12YEnzyme nomenclature (EC numbers)116
3C12PFermentation, enzyme processes112
4C12QMeasuring/testing involving enzymes91
5A61KMedicinal preparations81
6G01NInvestigating / analysing materials74
7A61PTherapeutic activity (drug indications)58
8C07KPeptides48
9Y10SCross-reference (legacy)25
10A23C18

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

See Cypris in action

Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
COATINGS AND SURFACE TREATMENTS HAVING ACTIVE ENZYMES AND PEPTIDES2009153
RAPID METHOD FOR DETERMINING EFFICACY OF A STERILIZATION CYCLE AND RAPID READ-OUT BIOLOGICAL INDICATOR19913M Co199
Ubiquitin protease2009Takeda Pharmaceutical Co Ltd85
Rapid read-out biological indicator19953M Co147
27411, a novel human PGP synthase2006Takeda Pharmaceutical Co Ltd92

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20164
20173
20191
20241

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1E FischerUniversity of Pecs5
2Attila AlmásiUniversity of Pecs4
3Alvan C. HenggeUtah State University3
4Pál PerjésiUniversity of Pecs3
5Masahiro HayashiTokyo University of Pharmacy and Life Sciences3
6Dong‐Hyun KimKyung Hee University3
7Eung‐Chil ChoiSeoul National University3
8Takashi MizumaTokyo University of Pharmacy and Life Sciences3
9Kyoichi KobashiTohoku Medical and Pharmaceutical University3
10Shoji AwazuTokyo University of Pharmacy and Life Sciences3

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

See Cypris in action

The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of p-Nitrophenyl sulfate?

p-Nitrophenyl sulfate has the molecular formula C6H5NO6S with a molecular weight of 219.167. Its canonical name is (4-nitrophenyl) hydrogen sulfate, and it is also known by several synonyms including 4-nitrophenyl sulfate, para-nitrophenyl sulfate, and sulfuric acid mono(4-nitrophenyl) ester.

Which organizations hold the most patents involving p-Nitrophenyl sulfate?

Steris PLC leads with 26 patents, followed by 3M Co with 18 patents. Other significant patent holders include DSM Firmenich AG and Massachusetts Institute of Technology, each with 12 patents, and Merck KGaA with 9 patents.

What research topics are associated with p-Nitrophenyl sulfate in published literature?

Published research on p-Nitrophenyl sulfate spans several topics including analytical chemistry and chromatography, enzyme catalysis and immobilization, dialysis and renal disease management, and pesticide exposure and toxicity. Representative papers address ion-pair HPLC methods for quantitation of 4-nitrophenol conjugates and arylsulfotransferase enzyme characterization.

How has patent activity involving p-Nitrophenyl sulfate trended in recent years?

Patent activity has been substantial and relatively consistent, with annual filings ranging from 12 to 29 patents over the period 2016–2024. Peak activity occurred in 2023 with 29 patents. In the last three years (2023–2025), 52 patents have been filed. Paper publications are less frequent, with only 1 paper in the last three years.

What are the primary technology classification areas for patents involving p-Nitrophenyl sulfate?

The dominant CPC subclasses are C12N (174 patents) and C12Y (116 patents), reflecting biotechnology and enzyme-related applications. Other significant areas include C12P (112 patents) for biotechnological processes, C12Q (91 patents) for analytical bioassays, and A61K (81 patents) for pharmaceutical formulations.

Turn any compound into a complete chemical intelligence landscape

Go beyond static compound data. Cypris resolves identities, patents, papers, and commercial signals into one AI-powered view - so your team can move from a single chemical question to a complete R&D, IP, and market landscape.

Schedule a free trial