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p-Iodoclonidine

N-(2,6-dichloro-4-iodophenyl)-4,5-dihydro-1H-imidazol-2-amine · also: p-Iodoclonidine hydrochloride

FormulaC9H8Cl2IN3
Mol. weight355.9885
PubChem CID4656
InChIKeyHSRPTPAPMBHRRJ-UHFFFAOYSA-N
SMILESC1CN=C(N1)NC2=C(C=C(C=C2Cl)I)Cl
134Patents
44Research papers
3Patents - last 3 years
1Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Nicox SA21
2Warner Lambert Co LLC9
3Acadia Pharmaceuticals Inc7
4American Regent Inc4
5Washington University in St. Louis3
6Fidelta doo2
7Kenvue Brands LLC2
8Alcon Vision LLC1
9Hospital for Sick Children HSC1
10Icahn School of Medicine at Mount Sinai1

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)101
2A61KMedicinal preparations98
3C07DHeterocyclic compounds36
4Y02AClimate change adaptation22
5C07CAcyclic and carbocyclic compounds16
6A61MDevices for introducing media into the body12
7C07KPeptides12
8A61LSterilising / disinfecting materials11
9C08LPolymer compositions (blends)11
10C08B3

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1John E. PiletzUniversity of Mississippi Medical Center7
2He ZhuUniversity of Mississippi Medical Center4
3James IngleseNational Center for Advancing Translational Sciences4
4Patricia DranchakNational Center for Advancing Translational Sciences4
5Paul ErnsbergerCase Western Reserve University4
6Ajit JadhavNational Center for Advancing Translational Sciences3
7Anton SimeonovNational Center for Advancing Translational Sciences3
8Jens ScholzUniversity of Lübeck3
9Adam YasgarNational Institutes of Health2
10Alexey ZakharovNational Institutes of Health2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of p-Iodoclonidine?

p-Iodoclonidine has the molecular formula C9H8Cl2IN3 and a molecular weight of 355.9885 g/mol. Its canonical chemical name is N-(2,6-dichloro-4-iodophenyl)-4,5-dihydro-1H-imidazol-2-amine.

Which organizations hold the most patents related to p-Iodoclonidine?

Nicox SA holds the largest patent portfolio with 21 patents, followed by Warner Lambert Co LLC with 9 patents and Acadia Pharmaceuticals Inc with 7 patents.

What are the main research areas covered by patents and publications on this compound?

The primary patent classifications are pharmaceutical preparations (A61P, 101 patents) and medicinal chemistry (A61K, 98 patents). Organic chemistry synthesis (C07D, 36 patents) and chemical processes (C07C, 16 patents) also feature prominently. Published research focuses on topics including imidazoline binding sites, adrenergic receptors, and hypertension pharmacology.

Who are the leading researchers publishing on p-Iodoclonidine?

John E. Piletz from University of Mississippi Medical Center is the most prolific author with 7 papers. Other notable contributors include He Zhu (University of Mississippi Medical Center, 4 papers), James Inglese, Patricia Dranchak, and Paul Ernsberger (each with 4 papers from their respective institutions).

How has research activity on p-Iodoclonidine changed in recent years?

Patent activity has remained modest but consistent, with 3 patents filed in the last 3 years. Publication output has declined significantly, with only 1 paper published in the last 3 years compared to 44 total papers in the dataset. Peak publication years were 2019 (4 papers) and 2016 (3 papers).

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