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Oxytocin

(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide · also: Piton S · Utedrin · Pitocin · Oxoject · Oxystin · Partocon

FormulaC43H66N12O12S2
Mol. weight1007.193
PubChem CID439302
InChIKeyXNOPRXBHLZRZKH-DSZYJQQASA-N
SMILESCC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N
47,533Patents
22,585Research papers22,538 indexed in detail
3,566Patents - last 3 years
1,062Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Johnson and Johnson930
2Pfizer Inc900
3Takeda Pharmaceutical Co Ltd653
4Novo Nordisk Fonden615
5C.H. Boehringer Sohn AG and Co KG414
6University of California354
7Roche Holding AG341
8BioNTech SE327
9Ferring Holding SA310
10Bayer AG278

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations27,341
2A61PTherapeutic activity (drug indications)22,091
3C07KPeptides9,627
4C12NMicroorganisms, enzymes7,139
5C07DHeterocyclic compounds5,898
6G01NInvestigating / analysing materials4,556
7A61MDevices for introducing media into the body3,858
8Y02AClimate change adaptation2,888
9C07CAcyclic and carbocyclic compounds2,236
10A61B1,839

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Tocolytic oxytocin receptor antagonists1995Merck and Co Inc134
Closed-loop system for infusing oxytocin1996131
Tocolytic oxytocin receptor antagonists1998Merck and Co Inc112
1,6 - SUBSTITUTED (3R,6R) -3- (2,3-DIHYDRO-1H-INDEN-2-YL)-2,5-PIPERAZINEDIONE DERIVATIVES AS OXYTOCIN RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PRE-TERM LABOUR, DYSMENORRHEA AND ENDOMETRIOSIS2006GSK PLC81
Carbostyril oxytocin receptor antagonists1994Merck and Co Inc79

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
2016463
2017574
2018502
2019476
2020492
2021554
2022495
2023445
2024416
2025201

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Gareth LengUniversity of Edinburgh100
2Inga D. NeumannUniversity of Regensburg91
3Keith M. KendrickUniversity of Electronic Science and Technology of China70
4Larry J. YoungEmory University70
5Kerstin Uvnäs‐MobergKarolinska Institutet68
6Vincent du VigneaudCornell University59
7Yoichi UetaUniversity of Occupational and Environmental Health Japan52
8Janet A. AmicoUniversity of Pittsburgh49
9Roderich WalterCity University of New York49
10Anna‐Riitta FuchsCornell University46

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

TitleYearCited byTopic
Oxytocin increases trust in humans20053693Attachment and Relationship Dynamics
The Oxytocin Receptor System: Structure, Function, and Regulation20013093Hypothalamic control of reproductive hormones
Rapid analysis of amino acids using pre-column derivatization19842522Analytical Chemistry and Chromatography
Mechanisms of action of transmitters and other substances on smooth muscle.19792194Pharmacological Effects of Natural Compounds
Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress20032098Child and Adolescent Psychosocial and Emotional Development

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of oxytocin?

Oxytocin has the molecular formula C43H66N12O12S2 and a molecular weight of 1007.193 g/mol.

Which organizations hold the most patents related to oxytocin?

Johnson and Johnson holds the most oxytocin-related patents with 930 patents, followed by Pfizer Inc with 900 patents, and Takeda Pharmaceutical Co Ltd with 653 patents.

What are the most-cited landmark papers on oxytocin in the knowledge base?

The most highly-cited paper is 'Oxytocin increases trust in humans' (2005) with 3,693 citations, addressing attachment and relationship dynamics. The second most-cited is 'The Oxytocin Receptor System: Structure, Function, and Regulation' (2001) with 3,093 citations, covering hypothalamic control of reproductive hormones.

Who are the most prolific researchers publishing on oxytocin?

Gareth Leng from University of Edinburgh leads with 100 papers, followed by Inga D. Neumann from University of Regensburg with 91 papers, and Keith M. Kendrick from University of Electronic Science and Technology of China with 70 papers.

What are the primary patent classification areas for oxytocin-related inventions?

Pharmaceutical formulations and preparations (A61K) dominate with 27,341 patents, followed by pharmaceutical preparations for specific therapeutic uses (A61P) with 22,091 patents, and peptide chemistry (C07K) with 9,627 patents.

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