Compounds

Oxytocin

IUPAC
1-[19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-butan-2-yl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Formula
C43H66N12O12S2
MW
1007.193 g/mol
InChIKey
XNOPRXBHLZRZKH-UHFFFAOYSA-N
SMILES
CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N
PubChem CID
5771

47,533 patents · 22,585 papers · 4,081 patents and 1,050 papers in the last 3 years.

Top assignees

  1. Alza Corp (930 patents)
  2. Takeda Pharmaceutical Co Ltd (634 patents)
  3. Boehringer Ingelheim Animal Health USA Inc (405 patents)

Notable patents

  1. Tocolytic oxytocin receptor antagonists (1995)
  2. Closed-loop system for infusing oxytocin (1996)
  3. Tocolytic oxytocin receptor antagonists (1998)

Notable papers

  1. Oxytocin increases trust in humans (2005)
  2. The Oxytocin Receptor System: Structure, Function, and Regulation (2001)
  3. Rapid analysis of amino acids using pre-column derivatization (1984)

Full landscape: every top assignee, author, patent, paper, and classification.

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Top assignees

AssigneePatents
Alza Corp930
Takeda Pharmaceutical Co Ltd634
Boehringer Ingelheim Animal Health USA Inc405
Ferring BV287
University of California San Diego UCSD277
Emisphere Technologies Inc276
Pharmacia and Upjohn Co262
Leland Stanford Junior University238
Novo Nordisk AS233
Massachusetts Institute of Technology228

Top authors

AuthorAffiliationPapers
Inga D. NeumannUniversity of Regensburg94
Gareth LengUniversity of Edinburgh93
C. Sue CarterUniversity of Illinois Chicago82
Kerstin Uvnäs‐MobergKarolinska Institutet64
Roderich WalterCity University of New York61
Janet A. AmicoUniversity of Pittsburgh59
Anna‐Riitta FuchsCornell University57
Antonio ArgiolasUniversity of Cagliari51
Larry J. YoungEmory University47
Maria Rosaria MelisUniversity of Cagliari40

Top patents

TitleYearAssigneeCitations
Tocolytic oxytocin receptor antagonists1995Merck and Co Inc134
Closed-loop system for infusing oxytocin1996PAGER; DAVID131
Tocolytic oxytocin receptor antagonists1998Merck and Co Inc112
1,6 - SUBSTITUTED (3R,6R) -3- (2,3-DIHYDRO-1H-INDEN-2-YL)-2,5-PIPERAZINEDIONE DERIVATIVES AS OXYTOCIN RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PRE-TERM LABOUR, DYSMENORRHEA AND ENDOMETRIOSIS2006Glaxo Group Ltd81
Tricyclic diazepine vasopressin antagonists and oxytocin antagonists1998AMERICAN CYANAMID COMPANY79

Top papers

TitleYearCitationsTopic
Oxytocin increases trust in humans20053672Attachment and Relationship Dynamics
The Oxytocin Receptor System: Structure, Function, and Regulation20013075Hypothalamic control of reproductive hormones
Rapid analysis of amino acids using pre-column derivatization19842512Analytical Chemistry and Chromatography
Mechanisms of action of transmitters and other substances on smooth muscle.19792192Pharmacological Effects of Natural Compounds
Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress20032081Child and Adolescent Psychosocial and Emotional Development

Patent classifications

CodeAreaPatents
A61KMedicinal preparations27,318
A61PTherapeutic activity (drug indications)22,079
C07KPeptides9,616
C12NMicroorganisms, enzymes7,136
C07DHeterocyclic compounds5,895
G01NInvestigating / analysing materials4,555
A61MDevices for introducing media into the body3,854
Y02AClimate change adaptation2,881
C07CAcyclic and carbocyclic compounds2,235
A61B1,837

Research topics

TopicPapers
Neuroendocrine regulation and behavior191
Maternal and Perinatal Health Interventions41
Reproductive Physiology in Livestock23
Maternal and fetal healthcare22
Preterm Birth and Chorioamnionitis9
Birth, Development, and Health5
Cardiovascular Issues in Pregnancy5
Electrolyte and hormonal disorders5
Reproductive System and Pregnancy5
Growth Hormone and Insulin-like Growth Factors4

Frequently asked questions

What is the molecular formula and weight of oxytocin?

Oxytocin has the molecular formula C43H66N12O12S2 and a molecular weight of 1007.193 g/mol.

Which organizations hold the most patents related to oxytocin?

Alza Corp leads with 930 patents, followed by Takeda Pharmaceutical Co Ltd with 634 patents, and Boehringer Ingelheim Animal Health USA Inc with 405 patents.

What are the major research areas covered by oxytocin literature?

Research on oxytocin spans multiple topics, with neuroendocrine regulation and behavior being the largest area with 191 papers. Other significant areas include maternal and perinatal health interventions with 41 papers and reproductive physiology in livestock with 23 papers.

Who are the most prolific authors publishing on oxytocin?

Inga D. Neumann from the University of Regensburg has published 94 papers on oxytocin, followed by Gareth Leng from the University of Edinburgh with 93 papers, and C. Sue Carter from the University of Illinois Chicago with 82 papers.

What do the patent trends reveal about oxytocin innovation in recent years?

Patent activity on oxytocin has remained substantial, with 2022 showing the highest recent count at 2050 patents. Over the last three years, there were 4081 patents filed. Paper publications also remain steady, with 1050 papers in the last three years, indicating continued research interest.