Book a demo

Chemical intelligence powered by cypris.ai

ouabain

3-[(1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one;octahydrate · also: Strodival, Strophoperm, Ouabain CRS, Purostrophan, Acocantherine, G-Strophanthin

FormulaC29H60O20
Mol. weight728.779
PubChem CID6364534
InChIKeyTYBARJRCFHUHSN-DMJRSANLSA-N
SMILESC[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2C[C@H]([C@@]3([C@@H]4[C@@H](CC[C@@]3(C2)O)[C@]5(CC[C@@H]([C@]5(C[C@H]4O)C)C6=CC(=O)OC6)O)CO)O)O)O)O.O.O.O.O.O.O.O.O
683Patents
16,433Research papers
21Patents - last 3 years
63Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Bristol Myers Squibb Co174
2Sigma Tau Industrie Farmaceutiche Riunite SpA30
3University of Tennessee Research Foundation30
4Bioveris Corp25
5Oncternal Therapeutics Inc20
6Aeterna Zentaris GmbH16
7Centre National de la Recherche Scientifique16
8Pfizer Corp SRL16
9Pfizer Inc16
10Merck Sharp & Dohme LLC15

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

Visit Cypris

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)533
2C07DHeterocyclic compounds434
3A61KMedicinal preparations320
4C07CAcyclic and carbocyclic compounds108
5G01NInvestigating / analysing materials67
6C07FOrganometallic compounds50
7C12QMeasuring/testing involving enzymes46
8C07J45
9C07HSugars and derivatives41
10C07KPeptides38

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

See Cypris in action

Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Heterogeneous immunoassay for digoxin using ouabain as a separation means1985Dade Behring Inc41
ASSAY METHODS INVOLVING OUABAIN1992University of Maryland, Baltimore39
Antibody having binding specificity for human ouabain1998University of Maryland, Baltimore36
Immunoassay for detecting human ouabain1995UNIVERSITY OF MARYLAND AT BALTIMORE12
Ouabain triacetate derivative compounds1991Abbott Laboratories4

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Ion Transport and Channel Regulation74
2Ion channel regulation and function23
3Cardiac electrophysiology and arrhythmias20
4Neuroscience and Neuropharmacology Research20
5Nitric Oxide and Endothelin Effects10
6Pancreatic function and diabetes10
7Erythrocyte Function and Pathophysiology9
8Amino Acid Enzymes and Metabolism8
9Physiological and biochemical adaptations8
10Metabolism and Genetic Disorders7

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

See Cypris in action

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Tai AkeraMichigan State University67
2Arnold SchwartzBaylor College of Medicine63
3John M. HamlynUniversity of Maryland, Baltimore48
4Erland ErdmannLMU Klinikum45
5Torben ClausenAarhus University40
6Amir AskariUniversity of Toledo Medical Center35
7David LichtsteinHebrew University of Jerusalem35
8Frans H. H. LeenenUniversity of Ottawa34
9Jerry B. LingrelUniversity of Cincinnati Medical Center31
10E. Edward BittarUniversity of Wisconsin–Madison30

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

See Cypris in action

The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of ouabain?

Ouabain has the molecular formula C29H60O20 and a molecular weight of 728.779 g/mol. Its canonical IUPAC name is 3-[(1R,3S,5S,8R,9S,10R,11R,13R,14S,17R)-1,5,11,14-tetrahydroxy-10-(hydroxymethyl)-13-methyl-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one;octahydrate.

Which organizations hold the most patents related to ouabain?

Bristol Myers Squibb Co holds the largest patent portfolio with 174 patents related to ouabain. Other major assignees include Sigma Tau Industrie Farmaceutiche Riunite SpA and University of Tennessee Research Foundation, each with 30 patents, followed by Bioveris Corp with 25 patents.

What are the primary research topics associated with ouabain in the scientific literature?

The dominant research topic is Ion Transport and Channel Regulation with 70 papers. Other significant areas include ion channel regulation and function (20 papers), cardiac electrophysiology and arrhythmias (19 papers), and Neuroscience and Neuropharmacology Research (18 papers). These topics reflect ouabain's role as a cardiac glycoside and ion pump modulator.

Who are the leading researchers publishing on ouabain?

Tai Akera from Michigan State University leads with 67 papers, followed by Arnold Schwartz from Baylor College of Medicine with 63 papers. Other prolific authors include John M. Hamlyn from University of Maryland, Baltimore (46 papers), Erland Erdmann from LMU Klinikum (45 papers), and Torben Clausen from Aarhus University (40 papers).

What are the primary patent classification areas for ouabain-related inventions?

The top patent classification is A61P (Specific therapeutic activity of chemical compounds or medicinal preparations) with 533 patents. This is followed by C07D (Heterocyclic compounds) with 434 patents and A61K (Preparations for medical, dental, or toilet purposes) with 320 patents, indicating that ouabain research focuses on pharmaceutical applications and chemical modifications.

Turn any compound into a complete chemical intelligence landscape

Go beyond static compound data. Cypris resolves identities, patents, papers, and commercial signals into one AI-powered view - so your team can move from a single chemical question to a complete R&D, IP, and market landscape.

Schedule a free trial