Book a demo

Chemical intelligence powered by cypris.ai

ONO-3708

(Z)-7-[(1S,2S,3S,5R)-3-[[(2R)-2-cyclopentyl-2-hydroxyacetyl]amino]-6,6-dimethyl-2-bicyclo[3.1.1]heptanyl]hept-5-enoic acid · also: (5Z)-7-((1S,2S,3S,5R)-3-(((2R)-2-Cyclopentyl-2-hydroxyacetyl)amino)-6,6-dimethylbicyclo(3.1.1)hept-2-yl)-5-heptenoic acid · (Z)-7-((1S,2S,3S,5R)-3-(((2R)-2-cyclopentyl-2-hydroxyacetyl)amino)-7,7-dimethyl-2-bicyclo(3.1.1)heptanyl)hept-5-enoic acid · (9,11)(11,12)-dideoxa-9 alpha,11 alpha-dimethylmethano-11,12-methano-13,14-dihydro-13-aza-14-oxo-15-cyclopentyl-16,17,18,19,20-pentanor-15-epi-TXA2

FormulaC23H37NO4
Mol. weight391.552
PubChem CID5311334
InChIKeySXHUZJPIRVLMHY-AZPSIHDESA-N
SMILESCC1([C@@H]2C[C@H]1[C@@H]([C@H](C2)NC(=O)[C@@H](C3CCCC3)O)C/C=C\CCCC(=O)O)C
41Patents
101Research papers100 indexed in detail
3Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Takeda Pharmaceutical Co Ltd10
2Bristol Myers Squibb Co4
3Vanderbilt University4
4Cumberland Pharmaceuticals Inc1
5Regeneron Pharmaceuticals Inc1

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations41
2A61PTherapeutic activity (drug indications)40
3Y02AClimate change adaptation5
4C07DHeterocyclic compounds1
5C12NMicroorganisms, enzymes1
6C12QMeasuring/testing involving enzymes1
7C12YEnzyme nomenclature (EC numbers)1
8G01NInvestigating / analysing materials1

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

See Cypris in action

Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Method of inhibiting side effects of solvents containing ricinoleic acid or castor oil or derivatives thereof employing a thromboxane A2 receptor antagonist and pharmaceutical compositions containing such solvents1995Bristol Myers Squibb Co62
Method of protecting against and/or treating ulcerative gastrointestinal conditions using a thromboxane A2 receptor antagonist and combination useful in preventing and/or treating ulcers and/or inflammation1994Bristol Myers Squibb Co40
Methods of potentiating organic nitrates having vasodilating activity and formulations for the same200110
Use of a thromboxane A2 receptor antagonist for the manufacture of a medicament for the treatment of ulcerative gastrointestinal conditions1991Bristol Myers Squibb Co13
Dual antagonist of PGD2/DPr2 and Thromboxane A2/TPr receptors and use for treatment of maladaptive immune response or thrombotic diathesis20231

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20161

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Hiroaki ShirahaseKyoto University8
2Kenji OkumuraNagoya University6
3Hachiro UsuiKyoto University6
4Yukio TokiNagoya University5
5Motohatsu FujiwaraKyoto University5
6Noboru TodaShiga University of Medical Science5
7Kazuyoshi KurahashiKyoto University5
8Hidekazu HashimotoNagoya University5
9Alan H. StephensonSaint Louis University4
10A. KodaGifu Pharmaceutical University4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

See Cypris in action

The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of ONO-3708?

ONO-3708 has a molecular formula of C23H37NO4 and a molecular weight of 391.552 g/mol.

Which organizations hold the most patents for ONO-3708?

Takeda Pharmaceutical Co Ltd holds the most patents with 10 patents, followed by Bristol Myers Squibb Co and Vanderbilt University, each with 4 patents.

What was the patent activity for ONO-3708 in recent years?

Patent activity increased significantly, with 7 patents filed in 2023, 4 in 2022, and 3 in 2021. In the last three years, there have been 3 total patents filed.

What is the primary research focus indicated by the patent classifications for ONO-3708?

The compound is predominantly classified under pharmaceutical and medicinal chemistry categories, with A61K (medicinal preparations) and A61P (specific therapeutic activity of chemical compounds) accounting for 41 and 40 patents respectively out of the total patent portfolio.

Which paper provides binding characterization data for ONO-3708 as a thromboxane receptor antagonist?

A paper titled 'Characterization of U46619 binding in unactivated, intact human platelets and determination of binding site affinities of four TXA2/PGH2 receptor antagonists (13-APA, BM 13.177, ONO 3708 and SQ 29,548)' published in 1986 addresses receptor binding affinity of ONO-3708.

Turn any compound into a complete chemical intelligence landscape

Go beyond static compound data. Cypris resolves identities, patents, papers, and commercial signals into one AI-powered view - so your team can move from a single chemical question to a complete R&D, IP, and market landscape.

Schedule a free trial