Book a demo

Chemical intelligence powered by cypris.ai

Oligomycin

(1R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-oxane]-3,9,13-trione · also: oligomycin A, Oligomycin A from Streptomyces diastatochromogenes

FormulaC45H74O11
Mol. weight791.076
PubChem CID52947716
InChIKeyMNULEGDCPYONBU-AWJDAWNUSA-N
SMILESCC[C@@H]\1CC[C@H]2[C@H]([C@H]([C@@H]([C@]3(O2)CC[C@@H]([C@@H](O3)C[C@@H](C)O)C)C)OC(=O)/C=C/[C@@H]([C@H]([C@@H](C(=O)[C@@H]([C@H]([C@@H](C(=O)[C@]([C@H]([C@@H](C/C=C/C=C1)C)O)(C)O)C)O)C)C)O)C)C
4,073Patents
84Research papers
503Patents - last 3 years
3Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Bristol Myers Squibb Co87
2University of California San Diego UCSD72
3Centre National de la Recherche Scientifique51
4Kikkoman Corp45
5Cornell University36
6Institut National de la Santé et de la Recherche Médicale36
7University of North Carolina at Chapel Hill35
8Rutgers, The State University of New Jersey33
9Meiji Seika Kaisha Ltd32
10Cartesian Therapeutics Inc29

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

Visit Cypris

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)2,670
2A61KMedicinal preparations2,596
3C12NMicroorganisms, enzymes1,216
4G01NInvestigating / analysing materials805
5C07KPeptides781
6C07DHeterocyclic compounds646
7C12QMeasuring/testing involving enzymes432
8C12PFermentation, enzyme processes270
9Y02AClimate change adaptation236
10C12YEnzyme nomenclature (EC numbers)231

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

See Cypris in action

Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Method for preparing oligomycin A and special for bacterial strain thereof2009CHINA AGRICULTURAL UNIVERSITY4
OLIGOMYCIN E1988Mitsubishi Chemical Corp4
OLIGOMYCIN SC COMPOUNDS AND ANTICANCER MEDICINE1997SAGAMI CHEM RES CENTER2
STRAIN STREPTOMYCES AVERMITILIS PBM 0004 PRODUCING OLIGOMYCINS2000DRINJAEV VIKTOR ANTONOVICH1
Process for the preparation of oligomycin A1986Bayer AG1

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Cell death mechanisms and regulation1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Andrey E. ShchekotikhinGause Institute of New Antibiotics Russian Academy of Medical Sciences6
2José Marco‐ContellesInstituto de Química Orgánica General6
3Lyudmila N. LysenkovaGause Institute of New Antibiotics Russian Academy of Medical Sciences6
4Natalia E. GrammatikovaGause Institute of New Antibiotics Russian Academy of Medical Sciences6
5Alexander M. KorolevGause Institute of New Antibiotics Russian Academy of Medical Sciences5
6Isabel IriepaUniversidad de Alcalá5
7Lyubov G. DezhenkovaGause Institute of New Antibiotics Russian Academy of Medical Sciences5
8Manuela G. LópezUniversidad Autónoma de Madrid4
9María Jesús Oset‐GasqueUniversidad Complutense de Madrid4
10Mourad ChiouaInstituto de Química Orgánica General4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

See Cypris in action

The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Oligomycin?

Oligomycin has the molecular formula C45H74O11 and a molecular weight of 791.076. Its IUPAC name reflects a complex spirocyclic structure with multiple hydroxyl and ketone groups.

Which organizations hold the most patents related to Oligomycin?

Bristol Myers Squibb Co leads with 87 patents, followed by University of California San Diego UCSD with 72 patents, and Centre National de la Recherche Scientifique CNRS with 51 patents. Other significant patent holders include Kikkoman Corp, Cornell University, and Institut National de la Sante et de la Recherche Medicale INSERM.

What are the primary research topics associated with Oligomycin in published literature?

The main research topics include Mitochondrial Function and Pathology, Drug Transport and Resistance Mechanisms, and Cell death mechanisms and regulation. Key published works examine Oligomycin's role as an inhibitor of oxidative phosphorylation and F0F1-ATPase.

How has patent activity for Oligomycin-related inventions changed in recent years?

Patent filings have shown substantial growth, increasing from 147 patents in 2016 to a peak of 326 in 2023. The three-year period through 2024 saw 518 new patent filings, indicating continued interest in Oligomycin applications and derivatives.

What are the leading patent classification areas for Oligomycin inventions?

The highest patent counts are in the A61P classification (2670 patents) covering pharmaceutical preparations, followed by A61K (2596 patents) for medicinal chemistry. Biotechnology-related classifications including C12N (1216 patents) and C12P (270 patents) also represent significant patent activity.

Turn any compound into a complete chemical intelligence landscape

Go beyond static compound data. Cypris resolves identities, patents, papers, and commercial signals into one AI-powered view - so your team can move from a single chemical question to a complete R&D, IP, and market landscape.

Schedule a free trial