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Norprolac

(3S,4aS,10aR)-3-(diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline · also: Quinagolide, Quinagolida, Quinagolidum

FormulaC20H33N3O3S
Mol. weight395.562
PubChem CID3086401
InChIKeyGDFGTRDCCWFXTG-ZIFCJYIRSA-N
SMILESCCCN1C[C@H](C[C@H]2[C@H]1CC3=C(C2)C(=CC=C3)O)NS(=O)(=O)N(CC)CC
1,935Patents
194Research papers
216Patents - last 3 years
3Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Bayer Pharma AG778
2Bayer AG327
3Bayer Intellectual Property GmbH136
4Deutsches Krebsforschungszentrum DKFZ130
5Dana Farber Cancer Institute Inc65
6Ferring BV50
7Case Western Reserve University36
8Harvard University33
9General Hospital Corp23
10Ceva Sante Animale SA21

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations1,693
2A61PTherapeutic activity (drug indications)1,684
3C07DHeterocyclic compounds1,016
4C07KPeptides126
5C07CAcyclic and carbocyclic compounds86
6C07FOrganometallic compounds76
7Y02AClimate change adaptation73
8G01NInvestigating / analysing materials72
9C07BGeneral methods of organic chemistry66
10C12QMeasuring/testing involving enzymes64

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
DRUG-DEVICE UNIT CONTAINING QUINAGOLIDE2016Ferring BV4
DRUG-DEVICE UNIT CONTAINING QUINAGOLIDE2017FERRING B. V.2
STEREOSELECTIVE SYNTHESIS OF INTERMEDIATES AND SYNTHESIS OF QUINAGOLIDS2024Ferring BV0
Pharmaceutical device unit containing quinagolide2023Ferring BV0
Drug-device unit containing quinagolide2016Ferring BV0

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Pituitary Gland Disorders and Treatments3
2Adrenal and Paraganglionic Tumors1
3Growth Hormone and Insulin-like Growth Factors1
4Hormonal and reproductive studies1
5TGF-β signaling in diseases1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Annamaria ColaoFederico II University Hospital19
2Judith BrownellRadboud University Nijmegen18
3Gaetano LombardiFederico II University Hospital16
4Antonella Di SarnoFederico II University Hospital11
5P. LacasseAgriculture and Agri-Food Canada11
6Carolina Di SommaFederico II University Hospital9
7Diego FeroneFederico II University Hospital9
8Bartolomeo MerolaFederico II University Hospital8
9Francesca SarnacchiaroFederico II University Hospital8
10Rosario PivonelloUniversity of Naples Federico II7

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical composition and molecular weight of Norprolac?

Norprolac has the molecular formula C20H33N3O3S with a molecular weight of 395.562. Its canonical chemical name is (3S,4aS,10aR)-3-(diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline, and it is also known by the synonyms Quinagolide, Quinagolida, and Quinagolidum.

Which organizations hold the most patents related to Norprolac?

Bayer Pharma AG holds the largest patent portfolio with 778 patents, followed by Bayer AG with 327 patents and Bayer Intellectual Property GmbH with 136 patents. Among non-Bayer organizations, Deutsches Krebsforschungszentrum DKFZ has 130 patents and Dana Farber Cancer Institute Inc has 65 patents.

What are the leading research topics in Norprolac literature?

The primary research topic is Pituitary Gland Disorders and Treatments, which appears in 3 papers. Additional topics include Adrenal and Paraganglionic Tumors, Hormonal and reproductive studies, and TGF-β signaling in diseases, each represented in 1 paper. Several foundational papers address Neurotransmitter Receptor Influence on Behavior and Growth Hormone and Insulin-like Growth Factors.

What recent patents have been filed on Norprolac drug-device formulations?

Recent patents on Norprolac drug-device units have been filed by Ferring BV, including a 2024 patent on stereoselective synthesis of quinagolide intermediates, a 2023 Chinese patent on pharmaceutical device units containing quinagolide, and earlier patents from 2016 on drug-device units containing quinagolide.

What is the patent classification profile for Norprolac-related intellectual property?

The patent portfolio is dominated by pharmaceutical and chemical classifications: A61K (1693 patents) covers pharmaceutical preparations, A61P (1684 patents) covers therapeutic applications, and C07D (1016 patents) covers heterocyclic organic compounds. Additional significant classes include C07K (126 patents) for peptide chemistry and C07C (86 patents) for acyclic and carbocyclic compounds.

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