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Benzocaine Hydrochloride

ethyl 4-aminobenzoate;hydrochloride · also: Neutracaine · Benzocaine (hydrochloride) · ethyl 4-aminobenzoate,hydrochloride · Ethyl 4-aminobenzoate hydrochloride · Ethyl p-aminobenzoate hydrochloride · 4-(Ethoxycarbonyl)anilinium chloride

FormulaC9H12ClNO2
Mol. weight201.65
PubChem CID10214462
InChIKeyJAADDQHUJDUAKW-UHFFFAOYSA-N
SMILESCCOC(=O)C1=CC=C(C=C1)N.Cl
153Patents
1,205Research papers1,193 indexed in detail
5Patents - last 3 years
21Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Hisamitsu Pharmaceutical Co Inc12
2Roche Holding AG6
3Xerox Holdings Corp6
4Kaneka Corp5
5Puretech Health PLC5
6Reckitt Benckiser Group PLC5
7Daiichi Sankyo Co Ltd4
8Takeda Pharmaceutical Co Ltd4
9AbbVie Inc3
10Astellas Pharma Inc3

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations79
2A61PTherapeutic activity (drug indications)63
3C07DHeterocyclic compounds29
4A61LSterilising / disinfecting materials20
5G01NInvestigating / analysing materials20
6A61N13
7C07CAcyclic and carbocyclic compounds13
8C08LPolymer compositions (blends)12
9G01K12
10C09DCoatings, paints, varnishes9

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
AMINOPHENYLPROPANOIC ACID DERIVATIVE2005Takeda Pharmaceutical Co Ltd146
Medical uses of styrene sulfonate polymers2001154
In situ formation of polymeric material2002Reckitt Benckiser Group PLC136
Monitoring system based on etching of metals201371
Methods and kits for maxillary dental anesthesia by means of a nasal deliverable anesthetic2002124

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
201621
201715
201818
201911
202012
20218
202211
202313
20247
20251

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1R. J. E. GroulsRadboud University Nijmegen8
2Eneida de PaulaUniversidade Estadual de Campinas (UNICAMP)6
3Alexander A. FisherNew York University4
4Joseph T. RubinoUniversity of North Carolina at Chapel Hill4
5Samuel H. YalkowskyUniversity of Arizona4
6A. M. RabascoUniversidad de Sevilla4
7G.Th.H. Van KempenLeiden University Medical Center4
8Alberto LesarriUniversidad de Valladolid4
9Stacey A. SecretoUniversity of Pennsylvania4
10Morton ShulmanRush University Medical Center4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Benzocaine Hydrochloride?

Benzocaine Hydrochloride has the molecular formula C9H12ClNO2 and a molecular weight of 201.65 g/mol. Its canonical name is ethyl 4-aminobenzoate;hydrochloride.

Which companies have the most patents involving Benzocaine Hydrochloride?

Hisamitsu Pharmaceutical Co Inc leads with 12 patents, followed by Roche Holding AG and Xerox Holdings Corp each with 6 patents, and Kaneka Corp, Puretech Health PLC, and Reckitt Benckiser Group PLC each with 5 patents.

What are the most common patent classifications associated with Benzocaine Hydrochloride?

The most frequent CPC subclasses are A61K with 79 patents, A61P with 63 patents, and C07D with 29 patents, indicating focus on pharmaceutical formulations, therapeutic applications, and heterocyclic compound synthesis.

How has patent activity around Benzocaine Hydrochloride changed in recent years?

Patent activity has been variable, with 14 patents in 2018, 10 in 2021, 6 in 2023, and 2 in 2024. In the last 3 years (2022–2024), only 5 patents have been filed, indicating declining recent activity.

Which academic authors have published the most research on Benzocaine Hydrochloride?

R. J. E. Grouls from Radboud University Nijmegen leads with 8 papers, followed by Eneida de Paula from Universidade Estadual de Campinas (UNICAMP) with 6 papers. Several other authors from institutions including New York University, University of North Carolina at Chapel Hill, and University of Arizona have each contributed 4 papers.

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