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Edetate calcium disodium

calcium;disodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate;hydrate · also: C10H14CaN2Na2O9, Natrii calcii edetas, Calcioedetato de sodio, Sodium calcium edetate, Calcium edetate de sodium, Calcium sodium edetate hydrate

FormulaC10H14CaN2Na2O9
Mol. weight392.2845
PubChem CID6096880
InChIKeyJHECKPXUCKQCSH-UHFFFAOYSA-J
SMILESC(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].O.[Na+].[Na+].[Ca+2]
1,208Patents
28,468Research papers
100Patents - last 3 years
720Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Mylan Specialty LP28
2Kala Bio Inc23
3Nippon Soda Co Ltd23
4Resonac Holdings Corp22
5Massachusetts Institute of Technology21
6Cydex Pharmaceuticals Inc16
7Denka Co Ltd16
8Wyeth LLC16
9Ezaki Glico Co Ltd12
10FMC Biopolymer AS8

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations620
2A61PTherapeutic activity (drug indications)555
3C07DHeterocyclic compounds180
4C07CAcyclic and carbocyclic compounds71
5C12NMicroorganisms, enzymes66
6C05G61
7C07KPeptides60
8Y02AClimate change adaptation60
9C05D58
10C05F58

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Endodontics and Root Canal Treatments51
2Platelet Disorders and Treatments27
3Enzyme function and inhibition19
4Peptidase Inhibition and Analysis15
5Alkaline Phosphatase Research Studies14
6Bacteriophages and microbial interactions13
7Blood properties and coagulation12
8Complement system in diseases12
9Erythrocyte Function and Pathophysiology12
10Iron Metabolism and Disorders12

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Domen LeštanUniversity of Ljubljana36
2Claude F. MearesUniversity of California, Davis34
3Matthias EiberTechnical University of Munich29
4Franklin R. TayAugusta University24
5Ali Afshar‐OromiehHeidelberg University22
6Benedikt KranzbühlerUniversity of Zurich7
7Ingvar BjarnasonMRC Clinical Trials Unit at UCL13
8Richard F. HurrellETH Zurich13
9David A. GoodwinStanford University12
10K. ItohShowa University6

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Edetate calcium disodium?

Edetate calcium disodium has the molecular formula C10H14CaN2Na2O9 and a molecular weight of 392.2845 g/mol. It is also known by the systematic name calcium disodium 2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetraacetate hydrate.

Which organizations hold the most patents related to Edetate calcium disodium?

Mylan Specialty LP holds the largest patent portfolio with 28 patents, followed by Kala Bio Inc and Nippon Soda Co Ltd, each with 23 patents. Other significant assignees include Resonac Holdings Corp with 22 patents and Massachusetts Institute of Technology with 21 patents.

What are the primary patent classification areas for compounds in this field?

The dominant patent classification area is A61K (pharmaceutical preparations), with 620 patents. This is closely followed by A61P (specific therapeutic activity of chemical compounds and preparations), with 555 patents. Other significant areas include C07D (heterocyclic compounds) with 180 patents and C07C (acyclic or carbocyclic compounds) with 71 patents.

Which research topics are most frequently studied in relation to this compound?

Endodontics and Root Canal Treatments is the most prominent research topic with 51 papers, followed by Platelet Disorders and Treatments with 27 papers. Other significant research areas include Enzyme function and inhibition with 19 papers and Peptidase Inhibition and Analysis with 15 papers.

What is the research publication trend for this compound in recent years?

The aggregate shows substantial research activity with 28,461 total papers in the database. In the last three years, there were 720 papers published. Peak publication activity occurred in 2022 with 409 papers, while 2023 saw 311 papers and 2024 had 300 papers. Patent filings have similarly remained active, with 100 patents filed in the last three years.

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