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Edetate calcium disodium

calcium;disodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate;hydrate · also: C10H14CaN2Na2O9 · Natrii calcii edetas · Calcioedetato de sodio · Sodium calcium edetate · Calcium edetate de sodium · Calcium sodium edetate hydrate

FormulaC10H14CaN2Na2O9
Mol. weight392.2845
PubChem CID6096880
InChIKeyJHECKPXUCKQCSH-UHFFFAOYSA-J
SMILESC(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].O.[Na+].[Na+].[Ca+2]
1,208Patents
28,468Research papers28,464 indexed in detail
91Patents - last 3 years
720Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Pfizer Inc28
2Viatris Inc28
3Kala Bio Inc23
4Nippon Soda Co Ltd23
5Resonac Holdings Corp22
6Massachusetts Institute of Technology21
7Denka Co Ltd16
8GSK PLC16
9Ligand Pharmaceuticals Inc16
10Ezaki Glico Co Ltd12

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations620
2A61PTherapeutic activity (drug indications)555
3C07DHeterocyclic compounds180
4C07CAcyclic and carbocyclic compounds71
5C12NMicroorganisms, enzymes66
6C05G61
7C07KPeptides60
8Y02AClimate change adaptation60
9C05D58
10C05F58

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
COMBINATORIAL ANALYSIS AND REPAIR2010Agilent Technologies Inc143
TREATMENT SYSTEMS FOR DELIVERY OF SENSITIZER SOLUTIONS2007119
COMPOSITION AND METHOD FOR IMPROVING STABILITY AND EXTENDING SHELF LIFE OF PROBIOTIC BACTERIA AND FOOD PRODUCTS THEREOF201261
Myc modulators and uses thereof2018Massachusetts Institute of Technology33
NASAL AND OPHTHALMIC DELIVERY OF AQUEOUS CORTICOSTEROID SOLUTIONS2008Ligand Pharmaceuticals Inc68

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
2016373
2017374
2018339
2019378
2020348
2021272
2022409
2023311
2024300
2025108
20261

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Domen LeštanUniversity of Ljubljana36
2Claude F. MearesUniversity of California, Davis26
3Uwe HaberkornHeidelberg University23
4Franklin R. TayAugusta University22
5Ali Afshar‐OromiehHeidelberg University20
6Nidambur Vasudev BallalManipal Academy of Higher Education16
7Wolfgang P. FendlerEssen University Hospital16
8Tobias MaurerTechnical University of Munich14
9Richard F. HurrellETH Zurich13
10Jérémie CalaisUniversity of California, Los Angeles13

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Edetate calcium disodium?

Edetate calcium disodium has the molecular formula C10H14CaN2Na2O9 and a molecular weight of 392.2845 g/mol. It is also known by the systematic name calcium;disodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate;hydrate.

Which organizations hold the most patents for Edetate calcium disodium?

Pfizer Inc and Viatris Inc each hold 28 patents related to Edetate calcium disodium, making them the leading patent assignees. Other significant patent holders include Kala Bio Inc and Nippon Soda Co Ltd, each with 23 patents.

How much research activity has there been around Edetate calcium disodium in recent years?

In the last three years (2022-2024), there were 195 patents filed and 720 papers published related to Edetate calcium disodium. The compound shows consistent research engagement, with 2024 containing 300 papers and 52 patents from the coverage dataset.

What are the primary technical classifications for patents involving Edetate calcium disodium?

Patents related to Edetate calcium disodium are predominantly classified under A61K (pharmaceutical preparations), which accounts for 620 patents, and A61P (therapeutic applications), which accounts for 555 patents. Additional significant classifications include C07D (heterocyclic compounds) with 180 patents and C07C (acyclic compounds) with 71 patents.

Who are the most prolific researchers publishing on Edetate calcium disodium?

The leading researchers by publication count include Domen Leštan from the University of Ljubljana with 36 papers, Claude F. Meares from the University of California, Davis with 26 papers, and Uwe Haberkorn from Heidelberg University with 23 papers. These researchers represent the most active authors in the field based on the coverage data.

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