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N-[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-N-hydroxyacetamide

N-[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-N-hydroxyacetamide

FormulaC14H16N2O4
Mol. weight276.292
PubChem CID121878
InChIKeyIWTCFIIOUXJOOV-OLZOCXBDSA-N
SMILESCC(=O)N([C@H]1[C@@H](C(OC2=C1C=C(C=C2)C#N)(C)C)O)O
29Patents
35Research papers
5Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1University of Pittsburgh15
2Tanabe Pharma Corp5
3Icahn School of Medicine at Mount Sinai1
4Incyte Corp1
5Incyte Holdings Corp1
6Soleno Therapeutics Inc1
7Universitaet Bielefeld1
8Yale University1

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)25
2A61KMedicinal preparations20
3C07DHeterocyclic compounds15
4C07KPeptides7
5C07CAcyclic and carbocyclic compounds6
6A01K3
7A61QCosmetics, personal care3
8C07FOrganometallic compounds3
9C12NMicroorganisms, enzymes3
10C08GPolymers from non-vinyl bonds (e.g. polyamides, polyesters)1

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Cardiac electrophysiology and arrhythmias1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Hidenari SakutaNational Defense Medical College9
2Masatoshi FujishimaKyushu University6
3Koichi OkamotoNational Defense Medical College5
4Setsuro IbayashiKyushu University5
5Takanari KitazonoKyushu University5
6Hikaru SuzukiNagoya City University4
7T NagaoKyushu University4
8Adam YasgarNational Institutes of Health2
9Ajit JadhavNational Institutes of Health2
10Alexey ZakharovNational Institutes of Health2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition and weight of this compound?

The compound has a molecular formula of C14H16N2O4 with a molecular weight of 276.292 g/mol. Its IUPAC name is N-[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-N-hydroxyacetamide.

Which organizations hold the most patents related to this compound?

University of Pittsburgh holds the largest patent portfolio with 15 patents, followed by Tanabe Pharma Corp with 5 patents. Other assignees include Icahn School of Medicine at Mount Sinai, Incyte Corp, Incyte Holdings Corp, Soleno Therapeutics Inc, Universitaet Bielefeld, and Yale University, each holding 1 patent.

What patent classification areas are most commonly associated with this compound?

The compound is predominantly classified under A61P (pharmaceutical preparations for specific therapeutic purposes) with 25 patents, followed by A61K (medicinal preparations) with 20 patents and C07D (heterocyclic compounds) with 15 patents. Other significant classifications include C07K (peptides), C07C (acyclic or carbocyclic compounds), and several others.

What is the recent patent activity trend for this compound?

Patent filings have shown variable activity over recent years, with 1 patent in 2017, 1 in 2018, 3 in 2020, 2 in 2022, 1 in 2023, 1 in 2024, and 3 projected for 2025. In the last 3 years, there have been 5 total patents filed.

What research topics are associated with published papers on this compound?

The 35 papers in the database cover diverse topics including asthma and respiratory diseases, muscle physiology and disorders, neuroscience and neuropharmacology research, heart failure treatment and management, and cardiac electrophysiology and arrhythmias. Key authors include Hidenari Sakuta, Masatoshi Fujishima, and Koichi Okamoto.

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