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N-[(2S)-1-[4-[(2S)-2-[(2,4-dichlorophenyl)sulfonylamino]-3-hydroxypropanoyl]piperazin-1-yl]-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide

N-[(2S)-1-[4-[(2S)-2-[(2,4-dichlorophenyl)sulfonylamino]-3-hydroxypropanoyl]piperazin-1-yl]-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide

FormulaC28H32Cl2N4O6S2
Mol. weight655.606
PubChem CID23630211
InChIKeyIVYQPSHHYIAUFO-VXKWHMMOSA-N
SMILESCC(C)C[C@@H](C(=O)N1CCN(CC1)C(=O)[C@H](CO)NS(=O)(=O)C2=C(C=C(C=C2)Cl)Cl)NC(=O)C3=CC4=CC=CC=C4S3
259Patents
140Research papers
69Patents - last 3 years
19Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Dompe Farmaceutici SpA14
2GlaxoSmithKline Intellectual Property No 2 Ltd14
3Pulmatrix Operating Co Inc14
4Dompe SpA8
5University of Utah Research Foundation Inc8
6Centre National de la Recherche Scientifique7
7Duke University7
8Pulmatrix Inc7
9BASF SE5
10Boston Children's Hospital5

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)225
2A61KMedicinal preparations194
3C07DHeterocyclic compounds112
4C07KPeptides46
5C12NMicroorganisms, enzymes40
6G01NInvestigating / analysing materials29
7C07FOrganometallic compounds26
8A01K14
9C12QMeasuring/testing involving enzymes13
10A61B12

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Ion Channels and Receptors2
2Gastrointestinal motility and disorders1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1David KrižajUniversity of Utah7
2Lei ChenNanjing Medical University7
3Ajit JadhavNational Center for Advancing Translational Sciences4
4Anton SimeonovNational Center for Advancing Translational Sciences4
5Chunfeng WuSecond Affiliated Hospital of Nanjing Medical University4
6Dong AnNanjing Medical University4
7Carleen Klumpp‐ThomasNational Center for Advancing Translational Sciences3
8Chen MenNanjing Medical University3
9Hongmao SunNational Center for Advancing Translational Sciences3
10Li ZhouNanjing Medical University3

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition and weight of this compound?

The compound has a molecular formula of C28H32Cl2N4O6S2 with a molecular weight of 655.606 g/mol. Its InChI Key is IVYQPSHHYIAUJO-VXKWHMMOSA-N.

Which organizations hold the most patents involving this compound?

The assignees with the highest patent counts are Dompe Farmaceutici SpA, GlaxoSmithKline Intellectual Property No 2 Ltd, and Pulmatrix Operating Co Inc, each holding 14 patents. Other significant holders include Dompe SpA and University of Utah Research Foundation Inc with 8 patents each.

What research topics are associated with this compound?

The compound is associated with research on Ion Channels and Receptors, with multiple papers studying its effects on channel function and vascular responses. Related topics include Gastrointestinal motility and disorders.

What is the historical publication trend for research on this compound?

Patent activity for this compound has grown substantially, peaking at 43 patents in 2022 and declining to 2 in 2026. Research papers show relatively consistent output from 2016-2020 (11-15 papers annually), with variable publication rates in subsequent years, including 11 papers in 2023 and 5 in 2024.

Which patent classification codes dominate the intellectual property landscape for this compound?

The compound is classified primarily under A61P (pharmaceutical preparations for therapy), A61K (preparations for medical purposes), and C07D (heterocyclic compounds), with 225, 194, and 112 patents respectively. Other significant classifications include C07K (peptides), C12N (microorganisms and enzymes), and G01N (investigating materials by determining properties).

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