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Miracol

1-[2-(diethylamino)ethylamino]-4-methylthioxanthen-9-one;hydrochloride · also: Nilodin, Scapuren, Tixantone, Miracil D, Lycanthone, Lucanthone HCl

FormulaC20H25ClN2OS
Mol. weight376.943
PubChem CID11054
InChIKeyLAOOXBLMIJHMFO-UHFFFAOYSA-N
SMILESCCN(CC)CCNC1=C2C(=C(C=C1)C)SC3=CC=CC=C3C2=O.Cl
4,372Patents
294Research papers
53Patents - last 3 years
1Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Boehringer Ingelheim Animal Health USA Inc272
2University of Pennsylvania71
3Novartis AG64
4Cerus Corp56
5Boehringer Ingelheim Vetmedica GmbH44
6F Hoffmann La Roche AG39
7Immunogen Inc36
8Celgene Corp33
9aTyr Pharma Inc32
10Pangu Biopharma Ltd31

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations1,962
2A61PTherapeutic activity (drug indications)1,922
3C07DHeterocyclic compounds938
4Y02AClimate change adaptation801
5C07KPeptides552
6C12NMicroorganisms, enzymes455
7A01NPreservation of bodies; biocides; pest repellents413
8G01NInvestigating / analysing materials161
9C07CAcyclic and carbocyclic compounds156
10C12QMeasuring/testing involving enzymes118

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Parasites and Host Interactions4
2Cancer therapeutics and mechanisms1
3Nematode management and characterization studies1
4Parasite Biology and Host Interactions1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Robert BasesAlbert Einstein College of Medicine11
2A. Halawani10
3Erich HirschbergColumbia University10
4J. NewsomeMedical Research Council9
5Sydney ArcherSterling Research Group (United States)9
6Dennis B. LeeperThomas Jefferson University Hospital7
7Frances MendezAlbert Einstein College of Medicine6
8J. Pellegrino5
9Andrew MilliganThomas Jefferson University Hospital4
10D. A. BerberianSterling Research Group (United States)4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the chemical composition and molecular weight of Miracol?

Miracol has the molecular formula C20H25ClN2OS and a molecular weight of 376.943. Its canonical name is 1-[2-(diethylamino)ethylamino]-4-methylthioxanthen-9-one;hydrochloride.

What are the major patent classification areas associated with Miracol?

The largest patent classification areas for Miracol are A61K (pharmaceuticals) with 1962 patents, A61P (medical uses of chemicals) with 1922 patents, and C07D (heterocyclic compounds) with 938 patents. Other significant areas include Y02A (climate change mitigation) with 801 patents and C07K (peptides) with 552 patents.

Which organizations hold the most patents related to Miracol?

The leading patent assignees are Boehringer Ingelheim Animal Health USA Inc with 272 patents, University of Pennsylvania Penn with 71 patents, and Novartis AG with 64 patents. Other major patent holders include Cerus Corp, Boehringer Ingelheim Vetmedica GmbH, and F Hoffmann La Roche AG.

What research topics are associated with Miracol in published literature?

Research papers on Miracol focus on several key topics including Parasites and Host Interactions, Cancer therapeutics and mechanisms, and Nematode management and characterization studies. Notable papers describe Miracol (also known as Lucanthone) as an inhibitor of autophagy, a frameshift mutagen, and an inhibitor of DNA repair activity in cancer cells.

How has patent activity for Miracol changed in recent years?

Patent activity for Miracol peaked in 2016 with 531 patents, followed by a decline to 233 patents in 2017. Activity has continued to decrease, with only 19 patents filed in 2024 and 16 in 2025. In contrast, recent paper publication on Miracol has been minimal, with only 1 paper published in the last 3 years.

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