Book a demo

Chemical intelligence powered by cypris.ai

Methylatropine nitrate

[(1R,5S)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate nitrate · also: Ekomine · Europen · Metanite · Eumydrin · Eumidrina · Eumydrine

FormulaC18H26N2O6
Mol. weight366.414
PubChem CID657381
InChIKeyNEDVJZNVOSNSHF-ZNHDNBJUSA-N
SMILESC[N+]1([C@@H]2CC[C@H]1CC(C2)OC(=O)C(CO)C3=CC=CC=C3)C.[N+](=O)([O-])[O-]
1,777Patents
437Research papers
69Patents - last 3 years
3Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Theravance Biopharma Inc170
2AstraZeneca PLC111
3Innoviva Inc104
4GSK PLC63
5Ligand Pharmaceuticals Inc44
6Pfizer Inc43
7Merck and Co Inc37
8Viatris Inc32
9AbbVie Inc31
10PTC Therapeutics Inc28

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

Visit Cypris

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)1,184
2A61KMedicinal preparations1,017
3C07DHeterocyclic compounds595
4C07KPeptides212
5A61MDevices for introducing media into the body110
6C12NMicroorganisms, enzymes105
7C07CAcyclic and carbocyclic compounds80
8G01NInvestigating / analysing materials80
9Y02AClimate change adaptation80
10C08LPolymer compositions (blends)69

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

See Cypris in action

Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssignee
Nejiyamas Ekomine Neji1983

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20162
20173
20195
20202
20211
20221
20232
20241

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Bo ÅhrénLund University8
2Rubens FazanUniversidade de São Paulo6
3Hugo Celso Dutra de SouzaUniversidade de São Paulo5
4Nicholas BodorUniversity of Florida4
5Paul S. BuckmasterStanford University4
6Cândido Celso CoimbraUniversidade Federal de Minas Gerais4
7Matthew D. HallNational Institutes of Health4
8Umeko MarubayashiUniversidade Federal de Minas Gerais4
9Hélio César SalgadoUniversidade de São Paulo4
10Thiago S. MoreiraUniversidade de São Paulo3

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

See Cypris in action

The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

TitleYearCited byTopic
Role of the Parasympathetic System in Airway Obstruction Due to Emphysema1984262Asthma and respiratory diseases
Selective hepatic vagotomy blocks pancreatic glucagon's satiety effect1983134Gastrointestinal motility and disorders

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of methylatropine nitrate?

Methylatropine nitrate has the molecular formula C18H26N2O6 and a molecular weight of 366.414 g/mol.

Which companies hold the most patents for methylatropine nitrate?

The top three patent assignees are Theravance Biopharma Inc with 170 patents, AstraZeneca PLC with 111 patents, and Innoviva Inc with 104 patents.

What are the primary patent classification areas for methylatropine nitrate research?

The leading CPC subclasses are A61P (pharmaceutical preparations for specific therapeutic effects) with 1184 patents, A61K (preparations for medical, dental, or toilet purposes) with 1017 patents, and C07D (heterocyclic compounds) with 595 patents.

How has patent activity for methylatropine nitrate trended in recent years?

Patent activity has declined over the long term, from 64 patents in 2016 to 23 patents in 2025. In the last three years, there have been 69 total patents filed. Paper publications have also remained limited, with only 3 papers in the last three years out of 437 total papers in the dataset.

What research topics are associated with methylatropine nitrate publications?

Published research has focused on topics including the role of the parasympathetic system in airway obstruction due to emphysema and the effects of selective hepatic vagotomy on pancreatic glucagon's satiety effect, indicating applications in respiratory and gastrointestinal therapeutic areas.

Turn any compound into a complete chemical intelligence landscape

Go beyond static compound data. Cypris resolves identities, patents, papers, and commercial signals into one AI-powered view - so your team can move from a single chemical question to a complete R&D, IP, and market landscape.

Schedule a free trial