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Met-enkephalin

(2S)-2-[[(2R)-2-[[2-[[2-[[(2R)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoic acid

FormulaC27H35N5O7S
Mol. weight573.665
PubChem CID6427062
InChIKeyYFGBQHOOROIVKG-BHIFYINESA-N
SMILESCSCC[C@@H](C(=O)O)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)[C@@H](CC2=CC=C(C=C2)O)N
2,554Patents
402Research papers
88Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Purdue Pharma LP174
2AbbVie Inc118
3Bausch Health Companies Inc102
4Johnson and Johnson90
5Pfizer Inc57
6Merck and Co Inc56
7Sanofi SA56
8Vertex Pharmaceuticals Inc51
9Japan Tobacco Inc45
10Leland Stanford Junior University43

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations1,744
2A61PTherapeutic activity (drug indications)1,731
3C07KPeptides950
4C07DHeterocyclic compounds611
5C12NMicroorganisms, enzymes393
6G01NInvestigating / analysing materials390
7C07CAcyclic and carbocyclic compounds139
8C12QMeasuring/testing involving enzymes118
9C12YEnzyme nomenclature (EC numbers)118
10Y02AClimate change adaptation98

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
USE OF MELANIN CONCENTRATING HORMONE AND MET-ENKEPHALIN AS THERAPEUTIC AGENTS2009Relief Therapeutics Holding SA4
USE OF MET-ENKEPHALIN AS A THERAPEUTIC AGENT2009Relief Therapeutics Holding SA3
Aerosol contg. met-enkephalin20062
USE OF MET-ENKEPHALIN AS A THERAPEUTIC AGENT2009Relief Therapeutics Holding SA0
USE OF MELANIN CONCENTRATING HORMONE AND MET-ENKEPHALIN AS THERAPEUTIC AGENTS2009Relief Therapeutics Holding SA0

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Santosh PashaInstitute of Genomics and Integrative Biology8
2Luisa GiariUniversity of Ferrara8
3Christoph SteinCharité - Universitätsmedizin Berlin7
4Heike L. RittnerFranklin University6
5Bahram Sayyaf DezfuliUniversity of Ferrara6
6Shaaban A. MousaFranklin University5
7Halina MachelskaFreie Universität Berlin4
8Susan IngramWashington State University Vancouver4
9David C. YeomansStanford University4
10Bernd A. BergFlorida State University4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Met-enkephalin?

Met-enkephalin has the molecular formula C27H35N5O7S with a molecular weight of 573.665 g/mol. Its InChI Key is YFGBQHOOROIVKG-BHIFYINESA-N.

Which organizations hold the most patents for Met-enkephalin?

Purdue Pharma LP holds the most patents with 174, followed by AbbVie Inc with 118 patents and Bausch Health Companies Inc with 102 patents. Johnson and Johnson, Pfizer Inc, Merck and Co Inc, and Sanofi SA each hold between 56 and 90 patents.

How much research activity has been documented for Met-enkephalin?

The aggregate contains 2554 patents and 402 papers related to Met-enkephalin. In the last three years, there were 88 new patents filed. Patent filings peaked in 2018 with 105 patents that year.

What therapeutic applications of Met-enkephalin have been patented?

Patents describe the use of Met-enkephalin as a therapeutic agent. One patent titled 'USE OF MET-ENKEPHALIN AS A THERAPEUTIC AGENT' was filed in 2009, and another describes the combined use of melanin concentrating hormone and Met-enkephalin as therapeutic agents. An aerosol formulation containing Met-enkephalin was also patented in 2006.

What research topics are most commonly associated with Met-enkephalin in peer-reviewed literature?

Published research on Met-enkephalin covers protein structure and dynamics, with a notably cited paper on the structure of Met-enkephalin in aqueous solution using molecular dynamics simulations. Other research topics include neurotransmitter receptor influence on behavior, stress responses, and pain management.

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