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Sphingosyl-phosphocholine

2-[[(E,2S,3R)-2-amino-3-hydroxyoctadec-4-enoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium · also: sphingosylphosphorylcholine · sphingosylphosphocholine acid · C18-Sphingosine phosphocholine · Sphingenyl-1-phosphorylcholine · D-erythro-sphingosylphosphorylcholine

FormulaC23H50N2O5P+
PubChem CID5280613
InChIKeyJLVSPVFPBBFMBE-HXSWCURESA-O
SMILESCCCCCCCCCCCCC/C=C/[C@H]([C@H](COP(=O)(O)OCC[N+](C)(C)C)N)O
181Patents
272Research papers
27Patents - last 3 years
9Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Boston Scientific Corp49
2AbbVie Inc21
3Opna Bio SA20
4Otsuka Holdings Co Ltd7
5Amorepacific Corp6
6University of California5
7Symrise AG4
8Corning Inc3
9Hebrew University of Jerusalem3
10Agency for Science, Technology and Research2

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations139
2A61PTherapeutic activity (drug indications)124
3C07KPeptides60
4G01NInvestigating / analysing materials47
5C07DHeterocyclic compounds44
6C12NMicroorganisms, enzymes27
7C07FOrganometallic compounds23
8C12QMeasuring/testing involving enzymes15
9A61QCosmetics, personal care14
10C07CAcyclic and carbocyclic compounds13

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
Application of sphingosylphosphorylcholine (SPC) in preparation of medicine for promoting endogenesis heart stem cells to be differentiated into heart lineage cells20155
Application of sphingosylphosphorylcholine in preparing anti-breast cancer drugs20161
Use of sphingosylphosphorylcholine antagonist for restoring the expression of antimicrobial peptides2009Amorepacific Corp1

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20169
20175
20185
20192
20206
20211
20225
20233
20245
20251

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Martin C. MichelUniversity of Amsterdam9
2Hiroko KishiYamaguchi University8
3Kid TörnquistMinerva Foundation7
4Sarah SpiegelGeorgetown University Medical Center7
5Dagmar Meyer zu HeringdorfEssen University Hospital7
6Jing ZhaoShandong University7
7Károly LiliomHungarian Academy of Sciences6
8Genji ImokawaKao Corporation (Japan)6
9Fumikazu OkajimaGunma University6
10Yoe‐Sik BaeSungkyunkwan University5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Sphingosyl-phosphocholine?

Sphingosyl-phosphocholine has the molecular formula C23H50N2O5P+ and is also known by its canonical name 2-[[(E,2S,3R)-2-amino-3-hydroxyoctadec-4-enoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium. Its InChI Key is JLVSPVFPBBFMBE-HXSWCURESA-O.

Which organizations hold the most patents related to Sphingosyl-phosphocholine?

Boston Scientific Corp leads with 49 patents, followed by AbbVie Inc with 21 patents and Opna Bio SA with 20 patents. Other significant patent holders include Otsuka Holdings Co Ltd, Amorepacific Corp, and University of California.

What are the primary research topics associated with Sphingosyl-phosphocholine in the scientific literature?

Key research topics include Protein Kinase Regulation and GTPase Signaling, Lysosomal Storage Disorders Research, Cellular transport and secretion, and Peroxisome Proliferator-Activated Receptors. Notable papers address its role as a ligand for G-protein-coupled receptors, its involvement in Niemann-Pick disease, and its critical role in platelet activation.

What are the primary patent classification areas for Sphingosyl-phosphocholine inventions?

The most frequently used patent classifications are A61K (139 patents) covering pharmaceutical preparations, A61P (124 patents) for therapeutic applications, and C07K (60 patents) for peptides and proteins. Additional significant classifications include G01N (47 patents) for measuring and testing, and C07D (44 patents) for organic compounds.

Who are the leading researchers publishing on Sphingosyl-phosphocholine?

The most prolific authors include Martin C. Michel from University of Amsterdam with 9 publications, Hiroko Kishi from Yamaguchi University with 8 publications, and Kid Törnquist, Sarah Spiegel, Dagmar Meyer zu Heringdorf, and Jing Zhao, each with 7 publications. These researchers contribute to diverse areas including cellular signaling and lysosomal disease research.

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