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Sphingosyl-phosphocholine

2-[[(E,2S,3R)-2-amino-3-hydroxyoctadec-4-enoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium · also: sphingosylphosphorylcholine, sphingosylphosphocholine acid, C18-Sphingosine phosphocholine, Sphingenyl-1-phosphorylcholine, D-erythro-sphingosylphosphorylcholine

FormulaC23H50N2O5P+
PubChem CID5280613
InChIKeyJLVSPVFPBBFMBE-HXSWCURESA-O
SMILESCCCCCCCCCCCCC/C=C/[C@H]([C@H](COP(=O)(O)OCC[N+](C)(C)C)N)O
181Patents
272Research papers
27Patents - last 3 years
9Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Apollo Endosurgery Inc48
2Opna Bio SA20
3Allergan Inc19
4Amorepacific Corp6
5Otsuka America Pharmaceutical Inc5
6Symrise AG4
7University of California, San Diego4
8Corning Inc3
9Lpath Therapeutics Inc3
10Yissum Research Development Co of Hebrew University of Jerusalem3

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This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations139
2A61PTherapeutic activity (drug indications)124
3C07KPeptides60
4G01NInvestigating / analysing materials47
5C07DHeterocyclic compounds44
6C12NMicroorganisms, enzymes27
7C07FOrganometallic compounds23
8C12QMeasuring/testing involving enzymes15
9A61QCosmetics, personal care14
10C07CAcyclic and carbocyclic compounds13

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Application of sphingosylphosphorylcholine (SPC) in preparation of medicine for promoting endogenesis heart stem cells to be differentiated into heart lineage cells2015SHANDONG UNIVERSITY5
Application of sphingosylphosphorylcholine in preparing anti-breast cancer drugs2016SHANDONG UNIVERSITY1
Use of sphingosylphosphorylcholine antagonist for restoring the expression of antimicrobial peptides2009Amorepacific Corp1

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Lysosomal Storage Disorders Research2
2Sphingolipid Metabolism and Signaling2
3Lipid Membrane Structure and Behavior1
4Mass Spectrometry Techniques and Applications1
5Pharmacological Effects of Natural Compounds1
6Protein Kinase Regulation and GTPase Signaling1

Technology trend analysis

Cypris uses AI to connect emerging research themes to IP activity, commercialization signals, and underexplored opportunity areas.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Jing ZhaoShandong University11
2Dagmar Meyer zu HeringdorfEssen University Hospital10
3Hiroko KishiYamaguchi University8
4Jae Ho KimPusan National University8
5Eun Su JeonPusan National University7
6Kid TörnquistMinerva Foundation7
7Fumikazu OkajimaGunma University6
8Genji ImokawaKao Corporation (Japan)6
9Ki‐Beom SuhrChungnam National University6
10Chang Hoon LeeDongguk University5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula of Sphingosyl-phosphocholine?

Sphingosyl-phosphocholine has the molecular formula C23H50N2O5P+, with the canonical IUPAC name 2-[[(E,2S,3R)-2-amino-3-hydroxyoctadec-4-enoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium.

Which organizations hold the most patents related to Sphingosyl-phosphocholine?

Apollo Endosurgery Inc holds the most patents with 48, followed by Opna Bio SA with 20 patents and Allergan Inc with 19 patents.

What are the primary research topics associated with Sphingosyl-phosphocholine in the literature?

The primary research topics include Lysosomal Storage Disorders Research, Sphingolipid Metabolism and Signaling, Protein Kinase Regulation and GTPase Signaling, and Lipid Membrane Structure and Behavior.

What are some key scientific findings about Sphingosyl-phosphocholine's biological role?

Sphingosylphosphorylcholine has been identified as a ligand for ovarian cancer G-protein-coupled receptor 1. It is also recognized as a membrane receptor ligand with high affinity in atrial myocytes, and has been identified as a key lipid critical for platelet activation.

What patent classification codes are most frequently used for Sphingosyl-phosphocholine inventions?

The most frequently used CPC classifications are A61K (139 patents) for pharmaceutical preparations, A61P (124 patents) for therapeutic applications, and C07K (60 patents) for organic compounds containing nitrogen.

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