Book a demo

Chemical intelligence powered by cypris.ai

Lasmiditan HCl

2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridinyl]benzamide;hydrochloride · also: COL-144 hydrochloride, LY-573144 Hydrochloride, Lasmiditan hydrochloride, Lasmiditan (hydrochloride), 2,4,6-Trifluoro-N-(6-(1-methylpiperidine-4-carbonyl)pyridin-2-yl)benzamide hydrochloride

FormulaC19H19ClF3N3O2
Mol. weight413.8252
PubChem CID17980336
InChIKeyYBTPRLDGGGYWIP-UHFFFAOYSA-N
SMILESCN1CCC(CC1)C(=O)C2=NC(=CC=C2)NC(=O)C3=C(C=C(C=C3F)F)F.Cl
67Patents
112Research papers
18Patents - last 3 years
23Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Eli Lilly and Co31
2Colucid Pharmaceuticals Inc6

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)65
2A61KMedicinal preparations46
3C07DHeterocyclic compounds41
4C07BGeneral methods of organic chemistry21
5Y02PClimate change mitigation: production15
6C07CAcyclic and carbocyclic compounds14
7C07KPeptides10
8Y02EClimate change mitigation: energy3

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

See Cypris in action

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1John H. KregeEli Lilly (United States)18
2Erin DotyEli Lilly (United States)10
3Mika KomoriEli Lilly (Japan)9
4Li Shen LooEli Lilly (United States)7
5Ellen B. DennehyPurdue University West Lafayette6
6Simin BayganiEli Lilly (United States)6
7Darren WilbrahamEli Lilly (United States)5
8Helen HochstetlerEli Lilly (United States)5
9Joel RaskinEli Lilly (United States)5
10Max TsaiEli Lilly (United States)5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

See Cypris in action

The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular composition of Lasmiditan HCl?

Lasmiditan HCl has the molecular formula C19H19ClF3N3O2 and a molecular weight of 413.8252. Its canonical chemical name is 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridinyl]benzamide;hydrochloride, with an InChI Key of YBTPRLDGGGYWIP-UHFFFAOYSA-N.

Which organizations hold the most patents related to Lasmiditan HCl?

Eli Lilly and Co holds 31 patents related to Lasmiditan HCl, making it the dominant patent assignee. Colucid Pharmaceuticals Inc holds 6 patents. Together, these two assignees account for a significant portion of the 67 total patents in the landscape.

What is the primary research focus in published literature on Lasmiditan HCl?

The published literature on Lasmiditan HCl is heavily focused on Migraine and Headache Studies. The highest-cited papers include Phase 3 randomized controlled trials and efficacy studies demonstrating its use as an acute treatment for migraine, with papers describing it as a 5-HT1F receptor agonist.

Who are the most prolific authors publishing research on Lasmiditan HCl?

John H. Krege from Eli Lilly (United States) is the most prolific author with 18 papers. Other leading contributors include Erin Doty with 10 papers, Mika Komori with 9 papers, and Li Shen Loo with 7 papers, all affiliated with Eli Lilly locations.

What patent classification codes are most relevant to Lasmiditan HCl technology?

The most common patent classification for Lasmiditan HCl is A61P (pharmaceutical activity), appearing in 65 patents. This is followed by A61K (medicinal preparations), with 46 patents, and C07D (heterocyclic compounds), with 41 patents, reflecting its pharmaceutical composition and therapeutic applications.

Turn any compound into a complete chemical intelligence landscape

Go beyond static compound data. Cypris resolves identities, patents, papers, and commercial signals into one AI-powered view - so your team can move from a single chemical question to a complete R&D, IP, and market landscape.

Schedule a free trial