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Lasmiditan HCl

2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridinyl]benzamide;hydrochloride · also: Lasmiditan hydrochloride

FormulaC19H19ClF3N3O2
Mol. weight413.8252
PubChem CID17980336
InChIKeyYBTPRLDGGGYWIP-UHFFFAOYSA-N
SMILESCN1CCC(CC1)C(=O)C2=NC(=CC=C2)NC(=O)C3=C(C=C(C=C3F)F)F.Cl
67Patents
112Research papers
20Patents - last 3 years
23Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Eli Lilly and Co31
2Colucid Pharmaceuticals Inc6

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)65
2A61KMedicinal preparations46
3C07DHeterocyclic compounds41
4C07BGeneral methods of organic chemistry21
5Y02PClimate change mitigation: production15
6C07CAcyclic and carbocyclic compounds14
7C07KPeptides10
8Y02EClimate change mitigation: energy3

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1John H. KregeEli Lilly (United States)18
2Erin DotyEli Lilly (United States)10
3Mika KomoriEli Lilly (Japan)9
4Li Shen LooEli Lilly (United States)7
5Ellen B. DennehyPurdue University West Lafayette6
6Simin BayganiEli Lilly (United States)6
7Darren WilbrahamEli Lilly (United States)5
8Helen HochstetlerEli Lilly (United States)5
9Joel RaskinEli Lilly (United States)5
10Max TsaiEli Lilly (United States)5

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Lasmiditan HCl?

Lasmiditan HCl has the molecular formula C19H19ClF3N3O2 and a molecular weight of 413.8252 g/mol.

Which organizations hold patents for Lasmiditan HCl?

The primary patent holders are Eli Lilly and Co with 31 patents and Colucid Pharmaceuticals Inc with 6 patents. In total, there are 67 patents covering this compound.

What is the primary clinical application of Lasmiditan HCl based on published research?

The primary clinical application is the acute treatment of migraine. Key publications include a phase 3 randomized, placebo-controlled, double-blind study and a phase 2 dose-ranging study demonstrating its efficacy as a 5-HT1F receptor agonist for migraine treatment.

Who are the most prolific authors publishing on Lasmiditan HCl?

The leading researchers are John H. Krege with 18 publications and Erin Doty with 10 publications, both affiliated with Eli Lilly in the United States. Other frequent contributors include Mika Komori from Eli Lilly Japan with 9 publications, and Li Shen Loo from Eli Lilly United States with 7 publications.

What patent classification categories are most relevant to Lasmiditan HCl?

The most common patent classifications are A61P (65 patents), covering therapeutic applications; A61K (46 patents), covering medicinal preparations; and C07D (41 patents), covering heterocyclic compounds. These reflect the compound's pharmaceutical and chemical synthesis aspects.

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