Book a demo

Chemical intelligence powered by cypris.ai

Isofraxidin

7-hydroxy-6,8-dimethoxychromen-2-one · also: Phytodolor, iso-Fraxidin, Isofraxidin (Standard), 6,8-Dimethoxyumbelliferone, Umbelliferone, 6,8-dimethoxy-, 6,8-dimethoxy-7-hydroxycoumarin

FormulaC11H10O5
Mol. weight222.196
PubChem CID5318565
InChIKeyHOEVRHHMDJKUMZ-UHFFFAOYSA-N
SMILESCOC1=C(C(=C2C(=C1)C=CC(=O)O2)OC)O
399Patents
64Research papers
31Patents - last 3 years
7Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Institute of Chinese Materia Medica of China Academy of Chinese Medical Sciences2
2Anhui Medical University1
3CapitalBio Corp1
4Excrx Singapore Pte Ltd1
5Kunming Institute of Botany1
6Lion Corp1
7South China Institute of Botany1
8University of Pennsylvania1
9Zhenping Power Supply Co of State Grid Henan Electric Power Co Ltd1

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

Visit Cypris

Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations112
2A61PTherapeutic activity (drug indications)53
3G01NInvestigating / analysing materials51
4Y02AClimate change adaptation41
5A23LFoods and beverages (general)25
6A61QCosmetics, personal care20
7A23VFoods, foodstuffs - indexing scheme14
8A01G10
9A01NPreservation of bodies; biocides; pest repellents10
10C07DHeterocyclic compounds10

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

See Cypris in action

Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Endophytic fungi capable of improving content of isofraxidin in Radix Acanthopanacis Semticosi through fermenting Radix Acanthopanacis Semticosi2012HEILONGJIANG UNIVERSITY6
Technology for synchronously extracting isofraxidin and flavonoids compounds from sarcandra glabra and applications thereof2010Sanming Huajian Bioengineering Co.Ltd5
One kind prepares isofraxidin method from Chinese medicinal material of sarcandra glaber2017GUANGDONG PROV. CHINESE MEDICINE HOSPITAL2
Method for extracting isofraxidin2011NANJING ZELANG AGRICULTURAL DEVELOPMENT CO., LTD.2
Isofraxidin crystalline compound and glabrous sarcandra herb dispersible tablets and dropping pills containing isofraxidin crystalline compound2012ZHEJIANG WECOME MEDICINE LNDUSTRY CO., LTD.1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Kaishun BiShenyang Pharmaceutical University6
2Haitao LvHeilongjiang University of Chinese Medicine5
3Hui SunShenyang Pharmaceutical University5
4Xijun WangHeilongjiang University of Chinese Medicine5
5Yanmei ZhangHeilongjiang University of Chinese Medicine5
6Hongxin CaoChina Academy of Chinese Medical Sciences4
7Taisuke YamazakiKohno Clinical Medicine Research Institute4
8Weifeng LiXi'an Jiaotong University4
9Takayoshi TokiwaKohno Clinical Medicine Research Institute3
10Ting FanXi'an Jiaotong University3

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

See Cypris in action

The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and structure of Isofraxidin?

Isofraxidin has the molecular formula C11H10O5 with a molecular weight of 222.196. Its canonical name is 7-hydroxy-6,8-dimethoxychromen-2-one, and it is a coumarin compound also known as 6,8-dimethoxyumbelliferone or 6,8-dimethoxy-7-hydroxycoumarin.

Which organizations hold patents for Isofraxidin applications?

Multiple assignees hold patents related to Isofraxidin. Notable patent holders include the Institute of Chinese Materia Medica of China Academy of Chinese Medical Sciences with 2 patents, and single-patent assignees including Anhui Medical University, CapitalBio Corp, Excrx Singapore Pte Ltd, Kunming Institute of Botany, Lion Corp, South China Institute of Botany, University of Pennsylvania, and Zhenping Power Supply Co of State Grid Henan Electric Power Co Ltd.

What are the primary research topics covered by publications on Isofraxidin?

Published research on Isofraxidin covers several key areas. Studies have examined natural product bioactivities and synthesis, drug transport and resistance mechanisms, and genomics with emphasis on phytochemicals and oxidative stress. Specific research has documented anti-inflammatory effects via the MAPK pathway, inhibition of matrix metalloproteinase-7 expression in hepatoma cells, and protective effects against radiation-induced apoptosis through reactive oxygen species scavenging.

Who are the most prolific authors publishing on Isofraxidin?

The most active researchers on Isofraxidin include Kaishun Bi from Shenyang Pharmaceutical University with 6 papers, followed by multiple authors each with 5 papers: Haitao Lv and Xijun Wang and Yanmei Zhang from Heilongjiang University of Chinese Medicine, and Hui Sun from Shenyang Pharmaceutical University. Additional prolific authors with 4 papers include Hongxin Cao from China Academy of Chinese Medical Sciences, Taisuke Yamazaki and Takayoshi Tokiwa from Kohno Clinical Medicine Research Institute, and Weifeng Li from Xi'an Jiaotong University.

What is the patent classification landscape for Isofraxidin?

The leading CPC subclass for Isofraxidin patents is A61K with 112 patents, followed by A61P with 53 patents and G01N with 51 patents. Other significant classifications include Y02A with 41 patents and A23L with 25 patents. Patents span pharmaceutical applications, testing methods, food composition, and cosmetic uses, reflecting the compound's broad applicability in health and food industries.

Turn any compound into a complete chemical intelligence landscape

Go beyond static compound data. Cypris resolves identities, patents, papers, and commercial signals into one AI-powered view - so your team can move from a single chemical question to a complete R&D, IP, and market landscape.

Schedule a free trial