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Intermedine

[(7R,8R)-7-hydroxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl]methyl (2S)-2-hydroxy-2-[(1R)-1-hydroxyethyl]-3-methylbutanoate · also: Intermedin, Intermedina, Melantropin, Intermedinum, Melanotropin, (+)-Intermedine

FormulaC15H25NO5
Mol. weight299.367
PubChem CID114843
InChIKeySFVVQRJOGUKCEG-OPQSFPLASA-N
SMILESC[C@H]([C@@](C(C)C)(C(=O)OCC1=CCN2[C@H]1[C@@H](CC2)O)O)O
5,144Patents
106Research papers
307Patents - last 3 years
0Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Alnylam Pharmaceuticals Inc571
2ModernaTx Inc161
3Amylin Pharmaceuticals LLC110
4Arbutus Biopharma Corp77
5Alza Corp70
6AstraZeneca Pharmaceuticals LP65
7Harvard University63
8Bayer Corp59
9Moderna Inc56
10Novo Nordisk AS55

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61KMedicinal preparations3,442
2A61PTherapeutic activity (drug indications)3,153
3C12NMicroorganisms, enzymes1,829
4C07KPeptides1,582
5C07DHeterocyclic compounds626
6G01NInvestigating / analysing materials609
7C07HSugars and derivatives418
8C12YEnzyme nomenclature (EC numbers)396
9Y02AClimate change adaptation359
10A61QCosmetics, personal care301

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Intermedin analogue prepared by bonding ring core sequence with biotin or cell-penetrating peptides2012ZHANG GA55
THERAPEUTIC USES OF INTERMEDIN 47 AND 53 PEPTIDES2009Mondobiotech Laboratories AG6
Therapeutic use of intermedin 47 peptide and intermedin 53 peptide2010モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト0
THERAPEUTIC USES OF INTERMEDIN 47 AND 53 PEPTIDES2009Mondobiotech Laboratories AG0
USE OF INTERMEDIN 47 PEPTIDE AS A THERAPEUTIC AGENT2009Mondobiotech Laboratories AG0

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Regulation of Appetite and Obesity1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Akiyoshi TakahashiKitasato University9
2Hiroshi KawauchiKitasato University8
3Helgi B. SchiöthUppsala University5
4Akikazu YasudaSuntory Foundation for Life Sciences4
5Liga ZvejnieceUniversity of Latvia4
6Ludger WitteTechnische Universität Braunschweig4
7Maija DambrovaLatvijas Organiskās Sintēzes Institūts4
8Robert M. DoresUniversity of Denver4
9Ruta MucenieceUniversity of Latvia4
10Tatjana HaitinaUppsala University4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Intermedine?

Intermedine has the molecular formula C15H25NO5 and a molecular weight of 299.367 g/mol.

How many patents and papers are associated with Intermedine in the dataset?

The dataset covers a total of 5144 patents and 106 papers related to Intermedine. In the last 3 years, there were 307 patents filed, though no papers were added during that period.

Which assignee has the most patents involving Intermedine?

Alnylam Pharmaceuticals Inc has the highest patent count with 571 patents in the Intermedine-related portfolio, followed by ModernaTx Inc with 161 patents.

What are the most common CPC subclasses for Intermedine patents?

The most prevalent CPC subclasses are A61K (3442 patents), A61P (3153 patents), C12N (1829 patents), and C07K (1582 patents), indicating focus on pharmaceutical preparations, medicinal uses, and biotechnology.

Which researchers have published the most papers on Intermedine?

Akiyoshi Takahashi from Kitasato University leads with 9 papers, followed by Hiroshi Kawauchi, also from Kitasato University, with 8 papers on Intermedine-related topics.

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