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Isoindigotin

3-(2-hydroxy-1H-indol-3-yl)indol-2-one · also: Isoindigo, 3,3'-biindole 2,2'(1h,1'h)-dione, (2-oxoindolin-3-ylidene)indolin-2-one, (3E)-3-(2-oxoindolin-3-ylidene)indolin-2-one, (3E)-3-(2-oxo-1H-indol-3-ylidene)-1H-indol-2-one, 1,1',3,3'-tetrahydro-3,3'-bis(2H-indol-3-ylidene)-2,2'-dione

FormulaC16H10N2O2
Mol. weight262.268
PubChem CID164610
InChIKeyVBMISAYWIMDRCV-UHFFFAOYSA-N
SMILESC1=CC=C2C(=C1)C(=C(N2)O)C3=C4C=CC=CC4=NC3=O
954Patents
28Research papers
231Patents - last 3 years
3Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1LG Chem Ltd40
2Institute of Chemistry27
3Oceans King Lighting Science and Technology Co Ltd16
4Hydro-Québec15
5Lubrizol Advanced Materials Inc15
6Murata Manufacturing Co Ltd15
7Shell Internationale Research Maatschappij BV15
8L'Oréal SA12
9Leland Stanford Junior University11
10University of Chinese Academy of Sciences10

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1H10KOrganic semiconductors / OLEDs304
2Y02EClimate change mitigation: energy291
3C07DHeterocyclic compounds207
4C08GPolymers from non-vinyl bonds (e.g. polyamides, polyesters)202
5A61PTherapeutic activity (drug indications)144
6A61KMedicinal preparations134
7C09KMaterials for misc. applications102
8H01LSemiconductor devices81
9C08FPolymers from C=C unsaturated bonds65
10C09DCoatings, paints, varnishes65

AI mapped opportunity space

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Derivative of isoindigo, indigo and indirubin for the treatment of cancer2003NATROGEN THERAPEUTICS, INC.23
Derivatives of isoindigo, indigo and indirubin and methods of treating cancer2005CHEN RUIHUAN19
CONJUGATED POLYMER CONTAINING ISOINDIGO UNITS, PREPARATION METHOD AND USE THEREOF2012Oceans King Lighting Science and Technology Co Ltd12
Isoindigo based co-polymer organic semiconductor material, and preparation method and application thereof2013Oceans King Lighting Science and Technology Co Ltd11
Isoindigo based co-polymer solar cell material, and preparation method and application thereof2013Oceans King Lighting Science and Technology Co Ltd11

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Cancer therapeutics and mechanisms1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Mustafa M. El‐AbadelahUniversity of Jordan5
2Ayman SalehNational Guard Health Affairs4
3Jalal A. ZahraUniversity of Jordan4
4Salim S. SabriUniversity of Jordan4
5Ahmad AljadaNational Guard Health Affairs3
6Mei‐Lin GoNational University of Singapore3
7Mohammad Azhar AzizNational Guard Health Affairs3
8Mutasem O. TahaUniversity of Jordan3
9Amre NasrKing Saud bin Abdulaziz University for Health Sciences2
10Baojie WanUniversity of Illinois Chicago2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and structure of Isoindigotin?

Isoindigotin has the molecular formula C16H10N2O2 with a molecular weight of 262.268. Its canonical name is 3-(2-hydroxy-1H-indol-3-yl)indol-2-one. The compound is also known by several alternative names including Isoindigo and (3E)-3-(2-oxo-1H-indol-3-ylidene)-1H-indol-2-one.

Which organizations hold the most patents involving Isoindigotin?

LG Chem Ltd leads with 40 patents, followed by Institute of Chemistry with 27 patents and Oceans King Lighting Science and Technology Co Ltd with 16 patents. Other significant patent holders include Hydro-Québec, Lubrizol Advanced Materials Inc, Murata Manufacturing Co Ltd, and Shell Internationale Research Maatschappij BV, each with 15 patents.

What are the primary technology areas where Isoindigotin is applied?

Isoindigotin is utilized across multiple technology domains. The dominant areas are organic electronics and photovoltaics (H10K with 304 patents), renewable energy (Y02E with 291 patents), and organic chemistry synthesis (C07D with 207 patents). Significant applications also exist in polymer chemistry (C08G with 202 patents) and pharmaceuticals for cancer therapy (A61P with 144 patents and A61K with 134 patents).

What research topics are associated with Isoindigotin studies?

Published research on Isoindigotin spans several areas including Cancer therapeutics and mechanisms, Organic Electronics and Photovoltaics, Asymmetric Synthesis and Catalysis, Nanoplatforms for cancer theranostics, and Toxic Organic Pollutants Impact. Notable studies include work on fluorine-substituted copolymers for photovoltaic performance, absorption spectra analysis, and donor-acceptor conjugated polymers for near-infrared modulated cancer treatment.

What is the recent patent activity trend for Isoindigotin?

Patent activity has grown significantly in recent years, with 2023 marking a peak at 118 patents. The three-year period from 2022 to 2024 accounted for 231 of the 954 total patents in the database. The trend shows substantial increases from 2019 (51 patents) through 2023 (118 patents), though activity declined to 101 patents in 2024 and 8 patents in 2025.

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