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Indin

3-(2-hydroxy-1H-indol-3-yl)indol-2-one · also: Isoindigo, Isoindigotin, trans-Isoindigo

FormulaC16H10N2O2
Mol. weight262.268
PubChem CID164610
InChIKeyVBMISAYWIMDRCV-UHFFFAOYSA-N
SMILESC1=CC=C2C(=C1)C(=C(N2)O)C3=C4C=CC=CC4=NC3=O
954Patents
28Research papers
241Patents - last 3 years
3Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1LG Chem Ltd40
2Institute of Chemistry27
3Oceans King Lighting Science and Technology Co Ltd16
4Hydro-Québec15
5Lubrizol Advanced Materials Inc15
6Murata Manufacturing Co Ltd15
7Shell Internationale Research Maatschappij BV15
8L'Oréal SA12
9Leland Stanford Junior University11
10University of Chinese Academy of Sciences10

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1H10KOrganic semiconductors / OLEDs304
2Y02EClimate change mitigation: energy291
3C07DHeterocyclic compounds207
4C08GPolymers from non-vinyl bonds (e.g. polyamides, polyesters)202
5A61PTherapeutic activity (drug indications)144
6A61KMedicinal preparations134
7C09KMaterials for misc. applications102
8H01LSemiconductor devices81
9C08FPolymers from C=C unsaturated bonds65
10C09DCoatings, paints, varnishes65

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Most-cited patents

Patents ranked by forward citations reveal the foundational inventions the field continues to build on.

TitleYearAssigneeCited by
Derivative of isoindigo, indigo and indirubin for the treatment of cancer2003NATROGEN THERAPEUTICS, INC.23
Derivatives of isoindigo, indigo and indirubin and methods of treating cancer2005CHEN RUIHUAN19
CONJUGATED POLYMER CONTAINING ISOINDIGO UNITS, PREPARATION METHOD AND USE THEREOF2012Oceans King Lighting Science and Technology Co Ltd12
Isoindigo based co-polymer organic semiconductor material, and preparation method and application thereof2013Oceans King Lighting Science and Technology Co Ltd11
Isoindigo based co-polymer solar cell material, and preparation method and application thereof2013Oceans King Lighting Science and Technology Co Ltd11

Where research is gaining momentum

Research themes ranked by publication activity show where scientific interest is accelerating around this compound.

#Research topicPapers
1Cancer therapeutics and mechanisms1

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Mustafa M. El‐AbadelahUniversity of Jordan5
2Ayman SalehNational Guard Health Affairs4
3Jalal A. ZahraUniversity of Jordan4
4Salim S. SabriUniversity of Jordan4
5Ahmad AljadaNational Guard Health Affairs3
6Mei‐Lin GoNational University of Singapore3
7Mohammad Azhar AzizNational Guard Health Affairs3
8Mutasem O. TahaUniversity of Jordan3
9Amre NasrKing Saud bin Abdulaziz University for Health Sciences2
10Baojie WanUniversity of Illinois Chicago2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular structure and formula of Indin?

Indin has the canonical chemical name 3-(2-hydroxy-1H-indol-3-yl)indol-2-one with the molecular formula C16H10N2O2 and a molecular weight of 262.268. It is also known by the synonyms Isoindigo, Isoindigotin, and trans-Isoindigo.

Which organizations hold the most patents related to Indin?

The leading patent assignees for Indin are LG Chem Ltd with 40 patents, Institute of Chemistry CAS with 27 patents, and Oceans King Lighting Science and Technology Co Ltd with 16 patents. Other significant holders include Hydro Quebec, Lubrizol Advanced Materials Inc, Murata Manufacturing Co Ltd, and Shell Internationale Research Maatschappij BV, each with 15 patents.

What are the primary research applications for Indin based on patent classifications?

The primary applications of Indin are reflected in its top CPC patent subclasses: H10K (304 patents, organic electronics), Y02E (291 patents, energy technologies), C07D (207 patents, organic chemistry), and C08G (202 patents, polymeric materials). Significant medical applications are indicated by A61P (144 patents, pharmaceutical activities) and A61K (134 patents, pharmaceutical formulations).

How has research activity on Indin evolved in recent years?

Patent activity on Indin has grown substantially, rising from 33 patents in 2016 to a peak of 118 patents in 2023, with 101 patents in 2024. The compound has been the subject of 28 research papers, with 3 papers published in the last 3 years. Overall, 250 patents have been filed in the last 3 years, indicating sustained and growing interest.

What therapeutic and materials science applications are documented in published research on Indin?

Documented research applications include cancer therapeutics, organic electronics and photovoltaics, asymmetric synthesis and catalysis, nanoplatforms for cancer theranostics, and toxicology studies of indigoid compounds. Notable examples include work on donor-acceptor conjugated polymers for near-infrared modulated cancer thermo-chemotherapy and enantioselective synthesis methods.

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