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Ibipinabant

(4S)-5-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide · also: ibipinabantum · C23H20Cl2N4O2S · (4S)-5-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-3,4-dihydropyrazole-2-carboxamidine · (S)-3-(4-chlorophenyl)-N''-(4-chlorophenylsulfonyl)-N-methyl-4-phenyl-4,5-dihydropyrazole-1-carboxamidine · (S)-3-(4-chlorophenyl)-N-(4-chlorophenylsulfonyl)-N''-methyl-4-phenyl-4,5-dihydropyrazole-1-carboxamidine · (4S)-3-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-4,5-dihydropyrazole-1-carboximidamide

FormulaC23H20Cl2N4O2S
Mol. weight487.399
PubChem CID9826744
InChIKeyAXJQVVLKUYCICH-OAQYLSRUSA-N
SMILESCN=C(NS(=O)(=O)C1=CC=C(C=C1)Cl)N2C[C@@H](C(=N2)C3=CC=C(C=C3)Cl)C4=CC=CC=C4
855Patents
29Research papers
91Patents - last 3 years
2Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1Bristol Myers Squibb Co150
2Sanofi SA123
3Pfizer Inc83
4Merck and Co Inc63
5Genfit SA24
6Abbott Laboratories18
7AbbVie Inc17
8Organon and Co14
9Lexicon Pharmaceuticals Inc11
10DSM Firmenich AG9

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)781
2C07DHeterocyclic compounds591
3A61KMedicinal preparations519
4C07CAcyclic and carbocyclic compounds106
5C07HSugars and derivatives102
6C07FOrganometallic compounds66
7C07KPeptides55
8C07BGeneral methods of organic chemistry43
9G01NInvestigating / analysing materials43
10C12QMeasuring/testing involving enzymes21

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Representative patents

The filings that best characterise the patent activity around this compound, most-referenced first.

TitleYearAssigneeCited by
DIPEPTIDE-BASED PRODRUG LINKERS FOR ALIPHATIC AMINE-CONTAINING DRUGS2011Ascendis Pharma AS179
DIOXA-BICYCLO[3.2.1.]OCTANE-2,3,4-TRIOL DERIVATIVES2010Pfizer Inc142
FLUORINATED HETEROARYLS2010Pfizer Inc106
BENZOIMIDAZOLE-CARBOXYLIC ACID AMIDE DERIVATIVES AS APJ RECEPTOR MODULATORS2014Sanofi SA78
TRIAZOLOPYRIDINE 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS2009Bristol Myers Squibb Co90

How research activity has moved

Papers published per year for this compound, over the last decade of indexed records.

YearPapers
20193
20201
20232

Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Mike TobynBristol-Myers Squibb (United Kingdom)6
2Matthew D. HallNational Institutes of Health4
3John F. GambleBristol-Myers Squibb (United Kingdom)3
4Andrew B. DennisBristol-Myers Squibb (Germany)3
5Bob StorkSolvay (Netherlands)2
6Tiny J. P. AdolfsSolvay (Netherlands)2
7Reşat ÇınarNational Institutes of Health2
8Rina SoniZydus Lifesciences Limited (India)2
9Andrew C. McCrearySolvay (Netherlands)2
10Anil Kumar Misra2

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Ibipinabant?

Ibipinabant has the molecular formula C23H20Cl2N4O2S with a molecular weight of 487.399 g/mol.

Which companies hold the most patents related to Ibipinabant?

Bristol Myers Squibb Co holds the most patents with 150, followed by Sanofi SA with 123 patents, and Pfizer Inc with 83 patents.

What are the primary research topics associated with Ibipinabant in the academic literature?

Published research on Ibipinabant focuses on drug solubility and delivery systems, including studies on physical stability and recrystallization kinetics of amorphous ibipinabant drug product, and formulation and process design for solid dosage forms containing spray-dried amorphous dispersions.

How has patent activity around Ibipinabant trended in recent years?

Patent activity has increased significantly, with 42 patents in 2023 and 46 in 2024, compared to 21 patents in 2016. The last three years (2023-2025) account for 91 of the total 855 patents.

What are the most common patent classification codes for Ibipinabant-related inventions?

The most prevalent CPC subclass is A61P (pharmaceutical preparations) with 781 patents, followed by C07D (heterocyclic compounds) with 591 patents, and A61K (medicinal preparations) with 519 patents.

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