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Hydromethylthionine mesylate

methanesulfonic acid;3-N,3-N,7-N,7-N-tetramethyl-10H-phenothiazine-3,7-diamine · also: Leucomethylene blue Mesylate, Leucomethylene Blue dimesylate, Leucomethylene Blue bismesylate

FormulaC18H27N3O6S3
Mol. weight477.609
PubChem CID60150609
InChIKeySPCMQFLNOVTUBM-UHFFFAOYSA-N
SMILESCN(C)C1=CC2=C(C=C1)NC3=C(S2)C=C(C=C3)N(C)C.CS(=O)(=O)O.CS(=O)(=O)O
272Patents
39Research papers
177Patents - last 3 years
4Papers - last 3 years

Who owns the IP

The organizations most actively patenting around this compound, ranked by referenced patent volume.

#AssigneePatents
1AC Immune SA25
2Genentech Inc22
3Washington University in St. Louis14
4University of Washington9
5Denali Therapeutics Inc5
6Tenaya Therapeutics Inc5
7University of California San Diego UCSD5
8Genting Taurx Diagnostic Centre Sdn Bhd4
9Genzyme Corp4
10University of California Berkeley4

Explore the full landscape

This preview shows the leading assignees. Cypris reveals the full ownership landscape - every filing entity, filing trends, and portfolio momentum.

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Where innovation is concentrated

Patent classifications ranked by volume reveal the technical domains with the most active filing.

#CodeAreaPatents
1A61PTherapeutic activity (drug indications)186
2A61KMedicinal preparations178
3C07KPeptides73
4G01NInvestigating / analysing materials68
5C07DHeterocyclic compounds51
6A61B29
7C12NMicroorganisms, enzymes26
8A23LFoods and beverages (general)21
9G16HDigital health, healthcare informatics21
10G06N17

AI mapped opportunity space

This preview shows where patent activity concentrates. Cypris maps the full classification landscape to surface technical whitespace and IP headroom.

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Who's driving the science

The most-published authors working with this compound, alongside their primary affiliations.

#AuthorAffiliationPapers
1Claude M. WischikUniversity of Aberdeen15
2Charles R. HarringtonUniversity of Aberdeen14
3Gernot RiedelUniversity of Aberdeen10
4John M. D. StoreyUniversity of Aberdeen6
5B. SchelterUniversity of Aberdeen5
6Peter BenthamTauRx (United Kingdom)5
7Diego MontiInstitute of Molecular Science and Technologies2
8Franz TheuringCharité - Universitätsmedizin Berlin4
9Helen ShiellsTauRx (United Kingdom)4
10Karima SchwabCharité - Universitätsmedizin Berlin4

Research leaders

This preview lists the top authors. Cypris surfaces the full researcher landscape, their affiliations, and how scientific influence is shifting.

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The literature that defines it

The most-cited papers anchoring the scientific record for this compound.

Frequently asked questions

Common questions about this compound's patent and research landscape, answered from the underlying data.

What is the molecular formula and weight of Hydromethylthionine mesylate?

Hydromethylthionine mesylate has the molecular formula C18H27N3O6S3 and a molecular weight of 477.609 g/mol. It is also known by several synonyms including Leucomethylene blue Mesylate and Leucomethylene Blue dimesylate.

Which organizations hold the most patents for Hydromethylthionine mesylate?

AC Immune SA holds the largest patent portfolio with 25 patents, followed by Genentech Inc with 22 patents and Washington University in St Louis WUSTL with 14 patents. Together, these three assignees represent a significant portion of the total 272 patents on record for this compound.

Who are the most prolific authors publishing research on this compound?

Claude M. Wischik and Charles R. Harrington, both affiliated with University of Aberdeen, are the most prolific authors, with 15 and 14 papers respectively. Gernot Riedel from the same institution has authored 10 papers on this compound.

What are the primary patent classification areas for Hydromethylthionine mesylate?

The compound is predominantly classified under therapeutic and pharmaceutical patents, with A61P (medicinal preparations for specific therapeutic purposes) accounting for 186 patents and A61K (preparations for medical purposes) for 178 patents. Chemical structure-related classifications including C07K and C07D represent 73 and 51 patents respectively.

What has been the recent trend in patent filings for this compound?

Patent activity for Hydromethylthionine mesylate has increased significantly in recent years. Of the total 272 patents, 180 were filed in the last three years, with 79 patents filed in both 2023 and 2024, representing a substantial acceleration compared to earlier years.

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